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Research ArticleEndocrinology

PET Imaging of Pancreatic Dopamine D2 and D3 Receptor Density with 11C-(+)-PHNO in Type 1 Diabetes

Jason Bini, Elizabeth Sanchez-Rangel, Jean-Dominique Gallezot, Mika Naganawa, Nabeel Nabulsi, Keunpoong Lim, Soheila Najafzadeh, Anupama Shirali, Jim Ropchan, David Matuskey, Yiyun Huang, Kevan C. Herold, Paul E. Harris, Robert S. Sherwin, Richard E. Carson and Gary W. Cline
Journal of Nuclear Medicine April 2020, 61 (4) 570-576; DOI: https://doi.org/10.2967/jnumed.119.234013
Jason Bini
1PET Center, Yale University School of Medicine, New Haven, Connecticut
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Elizabeth Sanchez-Rangel
2Department of Internal Medicine, Division of Endocrinology, Yale University School of Medicine, New Haven, Connecticut; and
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Jean-Dominique Gallezot
1PET Center, Yale University School of Medicine, New Haven, Connecticut
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Mika Naganawa
1PET Center, Yale University School of Medicine, New Haven, Connecticut
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Nabeel Nabulsi
1PET Center, Yale University School of Medicine, New Haven, Connecticut
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Keunpoong Lim
1PET Center, Yale University School of Medicine, New Haven, Connecticut
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Soheila Najafzadeh
1PET Center, Yale University School of Medicine, New Haven, Connecticut
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Anupama Shirali
1PET Center, Yale University School of Medicine, New Haven, Connecticut
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Jim Ropchan
1PET Center, Yale University School of Medicine, New Haven, Connecticut
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David Matuskey
1PET Center, Yale University School of Medicine, New Haven, Connecticut
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Yiyun Huang
1PET Center, Yale University School of Medicine, New Haven, Connecticut
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Kevan C. Herold
2Department of Internal Medicine, Division of Endocrinology, Yale University School of Medicine, New Haven, Connecticut; and
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Paul E. Harris
3Department of Medicine, Division of Endocrinology, Columbia University, New York, New York
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Robert S. Sherwin
2Department of Internal Medicine, Division of Endocrinology, Yale University School of Medicine, New Haven, Connecticut; and
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Richard E. Carson
1PET Center, Yale University School of Medicine, New Haven, Connecticut
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Gary W. Cline
2Department of Internal Medicine, Division of Endocrinology, Yale University School of Medicine, New Haven, Connecticut; and
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Article Information

vol. 61 no. 4 570-576
DOI 
https://doi.org/10.2967/jnumed.119.234013
PubMed 
31601695

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Published online April 1, 2020.

Article Versions

  • previous version (October 10, 2019 - 14:15).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2020 by the Society of Nuclear Medicine and Molecular Imaging.

Author Information

  1. Jason Bini1,
  2. Elizabeth Sanchez-Rangel2,
  3. Jean-Dominique Gallezot1,
  4. Mika Naganawa1,
  5. Nabeel Nabulsi1,
  6. Keunpoong Lim1,
  7. Soheila Najafzadeh1,
  8. Anupama Shirali1,
  9. Jim Ropchan1,
  10. David Matuskey1,
  11. Yiyun Huang1,
  12. Kevan C. Herold2,
  13. Paul E. Harris3,
  14. Robert S. Sherwin2,
  15. Richard E. Carson1 and
  16. Gary W. Cline2
  1. 1PET Center, Yale University School of Medicine, New Haven, Connecticut
  2. 2Department of Internal Medicine, Division of Endocrinology, Yale University School of Medicine, New Haven, Connecticut; and
  3. 3Department of Medicine, Division of Endocrinology, Columbia University, New York, New York
  1. For correspondence or reprints contact: Jason Bini, Department of Radiology and Biomedical Imaging, Yale University, 801 Howard Ave., P.O. Box 208048, New Haven, CT 06520. E-mail: jason.bini{at}yale.edu
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Journal of Nuclear Medicine: 61 (4)
Journal of Nuclear Medicine
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April 1, 2020
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PET Imaging of Pancreatic Dopamine D2 and D3 Receptor Density with 11C-(+)-PHNO in Type 1 Diabetes
Jason Bini, Elizabeth Sanchez-Rangel, Jean-Dominique Gallezot, Mika Naganawa, Nabeel Nabulsi, Keunpoong Lim, Soheila Najafzadeh, Anupama Shirali, Jim Ropchan, David Matuskey, Yiyun Huang, Kevan C. Herold, Paul E. Harris, Robert S. Sherwin, Richard E. Carson, Gary W. Cline
Journal of Nuclear Medicine Apr 2020, 61 (4) 570-576; DOI: 10.2967/jnumed.119.234013

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PET Imaging of Pancreatic Dopamine D2 and D3 Receptor Density with 11C-(+)-PHNO in Type 1 Diabetes
Jason Bini, Elizabeth Sanchez-Rangel, Jean-Dominique Gallezot, Mika Naganawa, Nabeel Nabulsi, Keunpoong Lim, Soheila Najafzadeh, Anupama Shirali, Jim Ropchan, David Matuskey, Yiyun Huang, Kevan C. Herold, Paul E. Harris, Robert S. Sherwin, Richard E. Carson, Gary W. Cline
Journal of Nuclear Medicine Apr 2020, 61 (4) 570-576; DOI: 10.2967/jnumed.119.234013
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Keywords

  • diabetes
  • pancreas
  • β-cell mass
  • PHNO
  • PET
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