Research ArticleRadiochemistry

Synthesis of the PET Tracer 124I-Trametinib for MAPK/ERK Kinase Distribution and Resistance Monitoring

Edwin C. Pratt, Elizabeth Isaac, Evan P. Stater, Guangbin Yang, Ouathek Ouerfelli, Nagavarakishore Pillarsetty and Jan Grimm
Journal of Nuclear Medicine December 2020, 61 (12) 1845-1850; DOI: https://doi.org/10.2967/jnumed.120.241901

Article Information

vol. 61 no. 12 1845-1850
DOI 
https://doi.org/10.2967/jnumed.120.241901
PubMed 
32444378
Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication January 23, 2020
  • Accepted for publication April 16, 2020
  • Published online December 1, 2020.

Article Versions

Copyright & Usage 
© 2020 by the Society of Nuclear Medicine and Molecular Imaging.

Author Information

  1. Edwin C. Pratt1,2,
  2. Elizabeth Isaac1,2,
  3. Evan P. Stater1,2,
  4. Guangbin Yang3,
  5. Ouathek Ouerfelli3,
  6. Nagavarakishore Pillarsetty2,4 and
  7. Jan Grimm1,2,4
  1. 1Department of Pharmacology, Weill Cornell Graduate School, New York, New York
  2. 2Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York
  3. 3Organic Synthesis Core, Memorial Sloan Kettering Cancer Center, New York, New York; and
  4. 4Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York
  1. For correspondence or reprints contact: Jan Grimm, Memorial Sloan Kettering Cancer Center, 1275 York Ave., Box 248, New York, NY 10021. E-mail: grimmj{at}mskcc.org
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