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Research ArticleThe State of the Art
Open Access

Combination Strategies to Improve Targeted Radionuclide Therapy

Tiffany G. Chan, Edward O’Neill, Christine Habjan and Bart Cornelissen
Journal of Nuclear Medicine November 2020, 61 (11) 1544-1552; DOI: https://doi.org/10.2967/jnumed.120.248062
Tiffany G. Chan
Department of Oncology, University of Oxford, Oxford, United Kingdom
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Edward O’Neill
Department of Oncology, University of Oxford, Oxford, United Kingdom
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Christine Habjan
Department of Oncology, University of Oxford, Oxford, United Kingdom
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Bart Cornelissen
Department of Oncology, University of Oxford, Oxford, United Kingdom
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Article Information

vol. 61 no. 11 1544-1552
DOI 
https://doi.org/10.2967/jnumed.120.248062
PubMed 
33037092

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication July 12, 2020
  • Accepted for publication September 9, 2020
  • Published online November 2, 2020.

Article Versions

  • previous version (October 9, 2020 - 13:53).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2020 by the Society of Nuclear Medicine and Molecular Imaging. Immediate Open Access: Creative Commons Attribution 4.0 International License (CC BY) allows users to share and adapt with attribution, excluding materials credited to previous publications. License: https://creativecommons.org/licenses/by/4.0/. Details: http://jnm.snmjournals.org/site/misc/permission.xhtml.

Author Information

  1. Tiffany G. Chan,
  2. Edward O’Neill,
  3. Christine Habjan and
  4. Bart Cornelissen
  1. Department of Oncology, University of Oxford, Oxford, United Kingdom
  1. For correspondence or reprints contact: Bart Cornelissen, Department of Oncology, MRC Oxford Institute for Radiation Oncology, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7LJ, United Kingdom. E-mail: bart.cornelissen{at}oncology.ox.ac.uk
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Journal of Nuclear Medicine: 61 (11)
Journal of Nuclear Medicine
Vol. 61, Issue 11
November 1, 2020
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Combination Strategies to Improve Targeted Radionuclide Therapy
Tiffany G. Chan, Edward O’Neill, Christine Habjan, Bart Cornelissen
Journal of Nuclear Medicine Nov 2020, 61 (11) 1544-1552; DOI: 10.2967/jnumed.120.248062

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Combination Strategies to Improve Targeted Radionuclide Therapy
Tiffany G. Chan, Edward O’Neill, Christine Habjan, Bart Cornelissen
Journal of Nuclear Medicine Nov 2020, 61 (11) 1544-1552; DOI: 10.2967/jnumed.120.248062
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  • Article
    • Abstract
    • INCREASING DNA DAMAGE WITH TRADITIONAL CHEMOTHERAPIES
    • RADIOSENSITIZATION THROUGH INHIBITING DNA REPAIR
    • RADIOSENSITIZATION THROUGH INHIBITING PHOSPHOINOSITIDE-3-KINASE/PROTEIN KINASE B/MAMMALIAN TARGET OF RAPAMYCIN (MTOR) SIGNALING
    • RADIOSENSITIZATION THROUGH INHIBITING HEDGEHOG SIGNALING
    • RADIOSENSITIZATION THROUGH INHIBITING P53–MURINE DOUBLE MINUTE 2 (MDM2) INTERACTIONS
    • RADIOSENSITIZATION THROUGH DISRUPTING CELL CYCLE
    • RADIOSENSITIZATION THROUGH DISRUPTING NICOTINAMIDE ADENINE DINUCLEOTIDE (NAD+) METABOLISM
    • RADIOSENSITIZATION THROUGH BLOCKING IMMUNE CHECKPOINTS
    • OUTLOOK
    • DISCLOSURE
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Keywords

  • targeted radionuclide therapy
  • combination therapy
  • radiotherapy
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