Article Figures & Data
Figures
- FIGURE 1.
Schematic illustration of cell components that may be relevant to heterogeneous cellular distribution.
- FIGURE 2.
Typical plasma pharmacokinetics of an antibody.
- FIGURE 3.
Typical plasma radiopharmacokinetics at fixed amount of radioactivity and different mass doses.
- FIGURE 4.
Different possible cellular fates of radiolabeled antibodies. (A) Binding to and dissociation from extracellular receptor. (B) Binding to extracellular receptor followed by internalization. (C and D) Transfer among lysosomal compartments. (E) Release of receptor and ligand from cell. (F) Lysosomal degradation of receptor or ligand. (G) Release of radionuclide from cell.
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