Epileptic Activity Increases Cerebral Amino Acid Transport Assessed by 18F-Fluoroethyl-l-Tyrosine Amino Acid PET: A Potential Brain Tumor Mimic

Markus Hutterer; Yvonne Ebner; Markus J. Riemenschneider; Antje Willuweit; Mark McCoy; Barbara Egger; Michael Schröder; Christina Wendl; Dirk Hellwig; Jirka Grosse; Karin Menhart; Martin Proescholdt; Brita Fritsch; Horst Urbach; Guenther Stockhammer; Ulrich Roelcke; Norbert Galldiks; Philipp T. Meyer; Karl-Josef Langen; Peter Hau; Eugen Trinka

doi:10.2967/jnumed.116.176610

Research ArticleNeurology

Epileptic Activity Increases Cerebral Amino Acid Transport Assessed by ¹⁸F-Fluoroethyl-l-Tyrosine Amino Acid PET: A Potential Brain Tumor Mimic

Markus Hutterer, Yvonne Ebner, Markus J. Riemenschneider, Antje Willuweit, Mark McCoy, Barbara Egger, Michael Schröder, Christina Wendl, Dirk Hellwig, Jirka Grosse, Karin Menhart, Martin Proescholdt, Brita Fritsch, Horst Urbach, Guenther Stockhammer, Ulrich Roelcke, Norbert Galldiks, Philipp T. Meyer, Karl-Josef Langen, Peter Hau and Eugen Trinka

Journal of Nuclear Medicine January 2017, 58 (1) 129-137; DOI: https://doi.org/10.2967/jnumed.116.176610

Markus Hutterer

1Department of Neurology, University of Regensburg Medical School, Regensburg, Germany

2Wilhelm Sander-Neurooncology Unit, University of Regensburg Medical School, Regensburg, Germany

3Department of Neurology and Centre for Cognitive Neuroscience, Christian-Doppler Klinik, Paracelsus Medical University Salzburg, Salzburg, Austria

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Yvonne Ebner

3Department of Neurology and Centre for Cognitive Neuroscience, Christian-Doppler Klinik, Paracelsus Medical University Salzburg, Salzburg, Austria

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Markus J. Riemenschneider

2Wilhelm Sander-Neurooncology Unit, University of Regensburg Medical School, Regensburg, Germany

4Department of Neuropathology, University of Regensburg Medical School, Regensburg, Germany

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Antje Willuweit

5Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany

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Mark McCoy

6Department of Radiology and Division of Neuroradiology, Christian-Doppler Klinik, Paracelsus Medical University Salzburg, Salzburg, Austria

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Barbara Egger

7Department of Nuclear Medicine, Landeskrankenhaus Salzburg, Paracelsus Medical University Salzburg, Salzburg, Austria

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Michael Schröder

1Department of Neurology, University of Regensburg Medical School, Regensburg, Germany

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Christina Wendl

8Department of Radiology and Division of Neuroradiology, University of Regensburg Medical School, Regensburg, Germany

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Dirk Hellwig

9Department of Nuclear Medicine, University of Regensburg Medical School, Regensburg, Germany

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Jirka Grosse

9Department of Nuclear Medicine, University of Regensburg Medical School, Regensburg, Germany

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Karin Menhart

9Department of Nuclear Medicine, University of Regensburg Medical School, Regensburg, Germany

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Martin Proescholdt

2Wilhelm Sander-Neurooncology Unit, University of Regensburg Medical School, Regensburg, Germany

10Department of Neurosurgery, University of Regensburg Medical School, Regensburg, Germany

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Brita Fritsch

11Department of Neurology, University Hospital Freiburg, Freiburg, Germany

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Horst Urbach

12Department of Neuroradiology, University Hospital Freiburg, Freiburg, Germany

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Guenther Stockhammer

13Department of Neurology, Medical University Innsbruck, Innsbruck, Austria

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Ulrich Roelcke

14Department of Neurology and Brain Tumor Center, Cantonal Hospital Aarau, Aarau, Switzerland

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Norbert Galldiks

5Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany

15Department of Neurology, University of Cologne, Cologne, Germany

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Philipp T. Meyer

16Department of Nuclear Medicine, University Hospital Freiburg, Freiburg, Germany; and

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Karl-Josef Langen

5Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany

17Department of Nuclear Medicine, University of Aachen, Aachen, Germany

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Peter Hau

1Department of Neurology, University of Regensburg Medical School, Regensburg, Germany

2Wilhelm Sander-Neurooncology Unit, University of Regensburg Medical School, Regensburg, Germany

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Eugen Trinka

3Department of Neurology and Centre for Cognitive Neuroscience, Christian-Doppler Klinik, Paracelsus Medical University Salzburg, Salzburg, Austria

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Epileptic Activity Increases Cerebral Amino Acid Transport Assessed by ¹⁸F-Fluoroethyl-l-Tyrosine Amino Acid PET: A Potential Brain Tumor Mimic

Journal of Nuclear Medicine Jan 2017, 58 (1) 129-137; DOI: 10.2967/jnumed.116.176610

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Epileptic Activity Increases Cerebral Amino Acid Transport Assessed by ¹⁸F-Fluoroethyl-l-Tyrosine Amino Acid PET: A Potential Brain Tumor Mimic

Journal of Nuclear Medicine Jan 2017, 58 (1) 129-137; DOI: 10.2967/jnumed.116.176610

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Keywords

epileptic seizure
status epilepticus
18F-FET PET
glioma
LAT1/2 expression

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