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Research ArticleBasic Science Investigations

PET Imaging of Tumor-Associated Macrophages with 89Zr-Labeled High-Density Lipoprotein Nanoparticles

Carlos Pérez-Medina, Jun Tang, Dalya Abdel-Atti, Brandon Hogstad, Miriam Merad, Edward A. Fisher, Zahi A. Fayad, Jason S. Lewis, Willem J.M. Mulder and Thomas Reiner
Journal of Nuclear Medicine August 2015, 56 (8) 1272-1277; DOI: https://doi.org/10.2967/jnumed.115.158956
Carlos Pérez-Medina
1Centro de Investigación en Red de Enfermedades Respiratorias, CIBERES, Madrid, Spain
2Centro Nacional de Investigaciones Cardiovasculares, CNIC, Madrid, Spain
3Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, New York
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Jun Tang
3Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, New York
4Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York
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Dalya Abdel-Atti
4Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York
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Brandon Hogstad
5Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York
6The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York
7Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York
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Miriam Merad
5Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York
6The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York
7Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York
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Edward A. Fisher
8Leon H. Charney Division of Cardiology and Marc and Ruti Bell Program in Vascular Biology, New York University School of Medicine, New York, New York
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Zahi A. Fayad
3Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, New York
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Jason S. Lewis
4Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York
9Weill Cornell Medical College, New York, New York; and
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Willem J.M. Mulder
3Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, New York
10Department of Vascular Medicine, Academic Medical Center of the University of Amsterdam, Amsterdam, The Netherlands
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Thomas Reiner
4Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York
9Weill Cornell Medical College, New York, New York; and
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Journal of Nuclear Medicine: 56 (8)
Journal of Nuclear Medicine
Vol. 56, Issue 8
August 1, 2015
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PET Imaging of Tumor-Associated Macrophages with 89Zr-Labeled High-Density Lipoprotein Nanoparticles
Carlos Pérez-Medina, Jun Tang, Dalya Abdel-Atti, Brandon Hogstad, Miriam Merad, Edward A. Fisher, Zahi A. Fayad, Jason S. Lewis, Willem J.M. Mulder, Thomas Reiner
Journal of Nuclear Medicine Aug 2015, 56 (8) 1272-1277; DOI: 10.2967/jnumed.115.158956

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PET Imaging of Tumor-Associated Macrophages with 89Zr-Labeled High-Density Lipoprotein Nanoparticles
Carlos Pérez-Medina, Jun Tang, Dalya Abdel-Atti, Brandon Hogstad, Miriam Merad, Edward A. Fisher, Zahi A. Fayad, Jason S. Lewis, Willem J.M. Mulder, Thomas Reiner
Journal of Nuclear Medicine Aug 2015, 56 (8) 1272-1277; DOI: 10.2967/jnumed.115.158956
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More in this TOC Section

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Keywords

  • tumor-associated macrophages
  • 89Zr
  • PET
  • high-density lipoprotein
  • breast cancer
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