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Research ArticleBasic Science Investigations

PET Imaging of Tumor-Associated Macrophages with 89Zr-Labeled High-Density Lipoprotein Nanoparticles

Carlos Pérez-Medina, Jun Tang, Dalya Abdel-Atti, Brandon Hogstad, Miriam Merad, Edward A. Fisher, Zahi A. Fayad, Jason S. Lewis, Willem J.M. Mulder and Thomas Reiner
Journal of Nuclear Medicine August 2015, 56 (8) 1272-1277; DOI: https://doi.org/10.2967/jnumed.115.158956
Carlos Pérez-Medina
1Centro de Investigación en Red de Enfermedades Respiratorias, CIBERES, Madrid, Spain
2Centro Nacional de Investigaciones Cardiovasculares, CNIC, Madrid, Spain
3Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, New York
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Jun Tang
3Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, New York
4Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York
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Dalya Abdel-Atti
4Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York
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Brandon Hogstad
5Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York
6The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York
7Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York
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Miriam Merad
5Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York
6The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York
7Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York
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Edward A. Fisher
8Leon H. Charney Division of Cardiology and Marc and Ruti Bell Program in Vascular Biology, New York University School of Medicine, New York, New York
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Zahi A. Fayad
3Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, New York
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Jason S. Lewis
4Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York
9Weill Cornell Medical College, New York, New York; and
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Willem J.M. Mulder
3Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, New York
10Department of Vascular Medicine, Academic Medical Center of the University of Amsterdam, Amsterdam, The Netherlands
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Thomas Reiner
4Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York
9Weill Cornell Medical College, New York, New York; and
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Article Information

vol. 56 no. 8 1272-1277
DOI 
https://doi.org/10.2967/jnumed.115.158956
PubMed 
26112022

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication April 7, 2015
  • Accepted for publication June 4, 2015
  • Published online August 3, 2015.

Article Versions

  • previous version (June 25, 2015 - 05:28).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2015 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

Author Information

  1. Carlos Pérez-Medina1–3,
  2. Jun Tang3,4,
  3. Dalya Abdel-Atti4,
  4. Brandon Hogstad5–7,
  5. Miriam Merad5–7,
  6. Edward A. Fisher8,
  7. Zahi A. Fayad3,
  8. Jason S. Lewis4,9,
  9. Willem J.M. Mulder3,10 and
  10. Thomas Reiner4,9
  1. 1Centro de Investigación en Red de Enfermedades Respiratorias, CIBERES, Madrid, Spain
  2. 2Centro Nacional de Investigaciones Cardiovasculares, CNIC, Madrid, Spain
  3. 3Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, New York
  4. 4Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York
  5. 5Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York
  6. 6The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York
  7. 7Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York
  8. 8Leon H. Charney Division of Cardiology and Marc and Ruti Bell Program in Vascular Biology, New York University School of Medicine, New York, New York
  9. 9Weill Cornell Medical College, New York, New York; and
  10. 10Department of Vascular Medicine, Academic Medical Center of the University of Amsterdam, Amsterdam, The Netherlands
  1. For correspondence or reprints contact either of the following: Thomas Reiner, Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave., New York, NY 10065. E-mail: reinert{at}mskcc.org
  2. W.J.M. Mulder, Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1234, New York, NY 10029. E-mail: willem.mulder{at}mssm.edu
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Journal of Nuclear Medicine: 56 (8)
Journal of Nuclear Medicine
Vol. 56, Issue 8
August 1, 2015
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PET Imaging of Tumor-Associated Macrophages with 89Zr-Labeled High-Density Lipoprotein Nanoparticles
Carlos Pérez-Medina, Jun Tang, Dalya Abdel-Atti, Brandon Hogstad, Miriam Merad, Edward A. Fisher, Zahi A. Fayad, Jason S. Lewis, Willem J.M. Mulder, Thomas Reiner
Journal of Nuclear Medicine Aug 2015, 56 (8) 1272-1277; DOI: 10.2967/jnumed.115.158956

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PET Imaging of Tumor-Associated Macrophages with 89Zr-Labeled High-Density Lipoprotein Nanoparticles
Carlos Pérez-Medina, Jun Tang, Dalya Abdel-Atti, Brandon Hogstad, Miriam Merad, Edward A. Fisher, Zahi A. Fayad, Jason S. Lewis, Willem J.M. Mulder, Thomas Reiner
Journal of Nuclear Medicine Aug 2015, 56 (8) 1272-1277; DOI: 10.2967/jnumed.115.158956
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