Research ArticleClinical Investigations

Thoracic Staging in Lung Cancer: Prospective Comparison of 18F-FDG PET/MR Imaging and 18F-FDG PET/CT

Philipp Heusch, Christian Buchbender, Jens Köhler, Felix Nensa, Thomas Gauler, Benedikt Gomez, Henning Reis, Georgios Stamatis, Hilmar Kühl, Verena Hartung and Till A. Heusner
Journal of Nuclear Medicine March 2014, 55 (3) 373-378; DOI: https://doi.org/10.2967/jnumed.113.129825

Article Figures & Data

Figures

  • FIGURE 1.
    FIGURE 1.

    18F-FDG–avid, histologically proven NSCLC in left upper lobe of 59-y-old female patient on T2-weighted blade MR image with measured maximum diameter of 3.7 cm (A) and on fused 18F-FDG PET/MR image (B). Identical tumor mass of same patient in left upper lobe on CT image with measured maximum diameter of 3.8 cm (C) and on 18F-FDG PET/CT image (D). Primary tumor was correctly staged as T2a tumor in 18F-FDG PET/MR imaging and 18F-FDG PET/CT.

  • FIGURE 2.
    FIGURE 2.

    Not pathologically enlarged suprahilar lymph node on left side in 71-y-old male patient with histologically proven NSCLC in left upper lung with short-axis diameter of 0.7 cm on T2-weighted blade MR image (A) and on fused 18F-FDG PET/MR image (B). Identical suprahilar lymph node of same patient on CT image with short-axis diameter of 0.7 cm (C) and on 18F-FDG PET/CT image (D). Histopathologically, lymph node was rated as benign (inflammatory changes).

  • FIGURE 3.
    FIGURE 3.

    Hilar lymph node on left side in 59-y-old female patient with histologically proven NSCLC in left upper lung on T2-weighted blade MR image with short-axis diameter of 1.3 cm (A). This lymph node shows pathologic 18F-FDG uptake on fused 18F-FDG PET/MR image (B). Identical hilar lymph node of same patient on CT image with short-axis diameter of 1.3 cm (C), clearly visible on 18F-FDG PET/CT image (D). Histopathologically, lymph node was rated as benign (inflammatory changes).

  • FIGURE 4.
    FIGURE 4.

    Bland–Altman analysis showing lower and upper limits of agreement between 18F-FDG PET/CT and 18F-FDG PET/MR imaging of −7.42 to 4.40 for SUVmax.

  • FIGURE 5.
    FIGURE 5.

    Bland–Altman analysis showing lower and upper limits of agreement between 18F-FDG PET/CT and 18F-FDG PET/MR imaging of −0.59 to 0.83 for tumor size.

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