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Journal of Nuclear Medicine

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Research ArticleFocus on Molecular Imaging

Current Progress of Aptamer-Based Molecular Imaging

Andrew Z. Wang and Omid C. Farokhzad
Journal of Nuclear Medicine March 2014, 55 (3) 353-356; DOI: https://doi.org/10.2967/jnumed.113.126144
Andrew Z. Wang
1Department of Radiation Oncology, Lineberger Comprehensive Cancer Center, Carolina Center for Cancer Nanotechnology Excellence, University of North Carolina–Chapel Hill, Chapel Hill, North Carolina
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Omid C. Farokhzad
2Laboratory of Nanomedicine and Biomaterials, Department of Anesthesiology, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts; and
3King Abdulaziz University, Jeddah, Saudi Arabia
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    FIGURE 1.

    Binding of 13C-RNA aptamer to G protein–coupled receptor kinase (GRK2). (Reprinted with permission of (20).)

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    FIGURE 2.

    Nuclear imaging with radiolabeled TTA1. Molecular probe is able to detect both U251 glioblastoma xenograft and MDA-MB-235 breast tumor xenograft.

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Journal of Nuclear Medicine: 55 (3)
Journal of Nuclear Medicine
Vol. 55, Issue 3
March 1, 2014
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Current Progress of Aptamer-Based Molecular Imaging
Andrew Z. Wang, Omid C. Farokhzad
Journal of Nuclear Medicine Mar 2014, 55 (3) 353-356; DOI: 10.2967/jnumed.113.126144

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Current Progress of Aptamer-Based Molecular Imaging
Andrew Z. Wang, Omid C. Farokhzad
Journal of Nuclear Medicine Mar 2014, 55 (3) 353-356; DOI: 10.2967/jnumed.113.126144
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  • Article
    • Abstract
    • APTAMERS AS MOLECULAR TARGETING LIGANDS
    • CLINICAL APPLICATIONS OF APTAMERS
    • OPTIC IMAGING WITH APTAMER-BASED PROBES
    • MR IMAGING
    • CT IMAGING
    • ULTRASOUND IMAGING
    • NUCLEAR IMAGING WITH APTAMER-BASED PROBES
    • CONCLUSION AND FUTURE DIRECTIONS
    • DISCLOSURE
    • Footnotes
    • REFERENCES
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  • Molecular Imaging of Pulmonary Fibrosis
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Keywords

  • aptamers
  • molecular imaging probes
  • molecular diagnostics
  • aptamer
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