RT Journal Article
SR Electronic
T1 Current Progress of Aptamer-Based Molecular Imaging
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 353
OP 356
DO 10.2967/jnumed.113.126144
VO 55
IS 3
A1 Wang, Andrew Z.
A1 Farokhzad, Omid C.
YR 2014
UL http://jnm.snmjournals.org/content/55/3/353.abstract
AB Aptamers, single-stranded oligonucleotides, are an important class of molecular targeting ligand. Since their discovery, aptamers have been rapidly translated into clinical practice. They have been approved as therapeutics and molecular diagnostics. Aptamers also possess several properties that make them uniquely suited to molecular imaging. This review aims to provide an overview of aptamers’ advantages as targeting ligands and their application in molecular imaging.