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Research ArticleBasic Science Investigation

In Vivo Formation of γ-H2AX and 53BP1 DNA Repair Foci in Blood Cells After Radioiodine Therapy of Differentiated Thyroid Cancer

Michael Lassmann, Heribert Hänscheid, Daniela Gassen, Johannes Biko, Viktor Meineke, Christoph Reiners and Harry Scherthan
Journal of Nuclear Medicine August 2010, 51 (8) 1318-1325; DOI: https://doi.org/10.2967/jnumed.109.071357
Michael Lassmann
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Heribert Hänscheid
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Daniela Gassen
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Johannes Biko
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Viktor Meineke
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Christoph Reiners
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Harry Scherthan
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Article Information

vol. 51 no. 8 1318-1325
DOI 
https://doi.org/10.2967/jnumed.109.071357
PubMed 
20660387

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication October 16, 2009
  • Accepted for publication December 2, 2009
  • Published online August 2, 2010.

Article Versions

  • previous version (July 21, 2010 - 13:45).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2010 by Society of Nuclear Medicine

Author Information

  1. Michael Lassmann1,
  2. Heribert Hänscheid1,
  3. Daniela Gassen2,
  4. Johannes Biko1,
  5. Viktor Meineke2,
  6. Christoph Reiners1 and
  7. Harry Scherthan2
  1. 1Department of Nuclear Medicine, University of Würzburg, Würzburg, Germany
  2. 2Bundeswehr Institute of Radiobiology, affiliated to the University of Ulm, Munich, Germany
  1. For correspondence or reprints contact: Michael Lassmann, Department of Nuclear Medicine, University of Würzburg, Oberdürrbacher Strasse 6, D-97080 Würzburg, Germany. E-mail: Lassmann_m{at}klinik.uni-wuerzburg.de
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  • DNA damage foci: Meaning and significance
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    Environmental and Molecular Mutagenesis 2015 56 6
  • Radioiodine Therapy in Benign Thyroid Diseases: Effects, Side Effects, and Factors Affecting Therapeutic Outcome
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    Endocrine Reviews 2012 33 6
  • γH2AX as a marker of DNA double strand breaks and genomic instability in human population studies
    Vanessa Valdiglesias, Simona Giunta, Michael Fenech, Monica Neri, Stefano Bonassi
    Mutation Research/Reviews in Mutation Research 2013 753 1
  • Persistent γH2AX: A promising molecular marker of DNA damage and aging
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    Mutation Research/Reviews in Mutation Research 2015 766
  • Ionizing radiation biomarkers for potential use in epidemiological studies
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    Mutation Research/Reviews in Mutation Research 2012 751 2
  • Low dose ionizing radiation effects on the immune system
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  • γ-H2AX and other histone post-translational modifications in the clinic
    Christophe E. Redon, Urbain Weyemi, Palak R. Parekh, Dejun Huang, Allison S. Burrell, William M. Bonner
    Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 2012 1819 7
  • Molecular radiotherapy: The NUKFIT software for calculating the time‐integrated activity coefficient
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  • Radiosensitivity in breast cancer assessed by the histone γ-H2AX and 53BP1 foci
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    Radiation Oncology 2013 8 1

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Journal of Nuclear Medicine: 51 (8)
Journal of Nuclear Medicine
Vol. 51, Issue 8
August 1, 2010
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In Vivo Formation of γ-H2AX and 53BP1 DNA Repair Foci in Blood Cells After Radioiodine Therapy of Differentiated Thyroid Cancer
Michael Lassmann, Heribert Hänscheid, Daniela Gassen, Johannes Biko, Viktor Meineke, Christoph Reiners, Harry Scherthan
Journal of Nuclear Medicine Aug 2010, 51 (8) 1318-1325; DOI: 10.2967/jnumed.109.071357

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In Vivo Formation of γ-H2AX and 53BP1 DNA Repair Foci in Blood Cells After Radioiodine Therapy of Differentiated Thyroid Cancer
Michael Lassmann, Heribert Hänscheid, Daniela Gassen, Johannes Biko, Viktor Meineke, Christoph Reiners, Harry Scherthan
Journal of Nuclear Medicine Aug 2010, 51 (8) 1318-1325; DOI: 10.2967/jnumed.109.071357
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