Article Figures & Data
Figures
- FIGURE 1.
Transaxial 18F-FDG PET/CT images demonstrate true-positive focus (arrow) representing recurrent oral cavity carcinoma 12 mo after surgery.
- FIGURE 2.
Transaxial 18F-FDG PET/CT images demonstrate false-positive focus (arrow) not confirmed by ultrasonography and follow-up of oral cavity carcinoma 12 mo after surgery.
- FIGURE 3.
Transaxial 18F-FDG PET/CT images demonstrate false-positive focus (arrow) corresponding after biopsy to Bartonella henselae infection 12 mo after surgery and radiochemotherapy of oral cavity carcinoma.
Tables
PET/CT Characteristic Negative (n = 52) Positive (n = 39) Mean age ± SD (y) 58.2 ± 10.2 57.2 ± 9.1 Sex (n) Male 45 33 Female 7 6 Original tumor site (n) Oral cavity 11 14 Oropharynx 15 11 Hypopharynx 7 5 Larynx 18 9 Nasopharynx 1 0 Initial stage (n) I 4 1 II 11 7 III 9 10 IV 28 21 Primary treatment Surgery alone 7 6 Surgery and radiotherapy 28 15 Radiotherapy alone 4 0 Concurrent chemotherapy 10 14 Induction chemotherapy followed by radiotherapy or surgery 3 4 Mean duration (±SD) after therapy (mo) 12.3 ± 4.1 10.7 ± 4.7 Confirmatory recurrence Patient no. Original tumor site Initial stage PET/CT finding Pathology Correlative imaging 1 Hypopharynx IV Local Negative — Distant (lung) — Positive 2 Larynx IV Distant (lung, bone, liver) — Positive 3 Oral cavity IV Local Positive — Regional (lymph nodes) Positive — 4 Oropharynx III Distant (lung) — Positive 5 Oropharynx III Local Positive — 6 Oropharynx IV Regional (lymph nodes) Positive — 7 Oropharynx IV Local Positive — 8 Larynx II Regional (lymph nodes) — Negative 9 Larynx IV Regional (lymph nodes) Positive — 10 Larynx IV Local Positive — 11 Oral cavity II Local Positive — 12 Larynx III Local Positive — Distant (lung) — Positive 13 Oropharynx IV Local Positive — 14 Hypopharynx IV Local Negative — 15 Oropharynx IV Distant (lung) — Negative 16 Oropharynx IV Distant (lung) Positive — 17 Oral cavity IV Distant (bone) — Positive 18 Oropharynx III Local Positive — 19 Hypopharynx II Local Positive — 20 Larynx IV Local Negative Positive Distant (lung) 21 Hypopharynx IV Distant (liver) Negative — 22 Oral cavity II Distant (lung) Positive 23 Hypopharynx IV Local Positive — Regional (lymph nodes) Positive — 24 Oral cavity II Distant (lung, bone, liver) — Positive 25 Oropharynx IV Local Positive — 26 Oral cavity II Local Positive — 27 Larynx IV Local Negative — 28 Larynx III Local Negative — 29 Oral cavity IV Local Positive — 30 Oropharynx II Local Positive — 31 Oral cavity III Local Positive — Distant (lung) — Positive 32 Oropharynx IV Local Negative — 33 Oral cavity I Regional (lymph nodes) — Negative 34 Oral cavity IV Local Positive — 35 Larynx IV Local Positive — Distant (lung) — Positive 36 Oral cavity III Distant (lymph nodes) Negative — 37 Oral cavity III Local Positive — 38 Oral cavity IV Distant (lung) Positive — 39 Oral cavity III Local Positive — Patients 1 and 20: true-positive for one localization and false-positive for the other.
Patient 37: true-positive for one localization and false-negative for the other (regional lymph nodes).
- TABLE 3
Diagnostic Value of 18F-FDG PET/CT in Detection of Recurrence for 91 HNSCC Asymptomatic Patients
PET/CT result Confirmatory recurrence Positive Negative Total Positive recurrence 30 0 30 Negative recurrence 9 52 61 Total 39 52 91
Jump to section
Related Articles
Cited By...
- Diagnostic Performance of 18F-FDG PET/CT According to Delay After Treatment to Detect Subclinical Recurrence of Head and Neck Squamous Cell Carcinoma
- Preliminary Results from Retrospective Correlation of Circulating Tumor DNA (ct-DNA) with Imaging for HPV-Positive Oropharyngeal Squamous Cell Carcinoma
- PET/CT Versus Standard Imaging for Prediction of Survival in Patients with Recurrent Head and Neck Squamous Cell Carcinoma
- Guideline Familiarity Predicts Variation in Self-Reported Use of Routine Surveillance PET/CT by Physicians Who Treat Head and Neck Cancer
- Head and Neck Cancers, Version 2.2014
- Osteoradionecrosis after Radiation Therapy for Head and Neck Cancer: Differentiation from Recurrent Disease with CT and PET/CT Imaging
- PET/CT Imaging and Human Papilloma Virus-Positive Oropharyngeal Squamous Cell Cancer: Evolving Clinical Imaging Paradigm
- Addition of 18F-FDG PET/CT to Clinical Assessment Predicts Overall Survival in HNSCC: A Retrospective Analysis with Follow-up for 12 Years
- Early Detection of Recurrent Disease by FDG-PET/CT Leads to Management Changes in Patients With Squamous Cell Cancer of the Head and Neck
- The Lack of Evidence for PET or PET/CT Surveillance of Patients with Treated Lymphoma, Colorectal Cancer, and Head and Neck Cancer: A Systematic Review
- Performance of Whole-Body PET/CT for the Detection of Distant Malignancies in Various Cancers: A Systematic Review and Meta-Analysis
- The role of positron emission tomography/CT imaging in head and neck cancer patients after radical chemoradiotherapy
- Head and Neck Cancers
- Innovations in Radiotherapy Planning of Head and Neck Cancers: Role of PET
- 18F-FDG PET as a Routine Posttreatment Surveillance Tool in Oral and Oropharyngeal Squamous Cell Carcinoma: A ProspectiveStudy