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OtherBasic Science Investigations

Comparative Evaluation of Serotonin Transporter Radioligands 11C-DASB and 11C-McN 5652 in Healthy Humans

W. Gordon Frankle, Yiyun Huang, Dah-Ren Hwang, Peter S. Talbot, Mark Slifstein, Ronald Van Heertum, Anissa Abi-Dargham and Marc Laruelle
Journal of Nuclear Medicine April 2004, 45 (4) 682-694;
W. Gordon Frankle
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Yiyun Huang
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Dah-Ren Hwang
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Peter S. Talbot
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Mark Slifstein
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Ronald Van Heertum
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Anissa Abi-Dargham
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Marc Laruelle
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Article Information

vol. 45 no. 4 682-694
PubMed 
15073266

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Published online April 8, 2004.

Copyright & Usage 
THE JOURNAL OF NUCLEAR MEDICINE

Author Information

  1. W. Gordon Frankle, MD1,
  2. Yiyun Huang, PhD1,2,
  3. Dah-Ren Hwang, PhD1,2,
  4. Peter S. Talbot, MD1,
  5. Mark Slifstein, PhD1,
  6. Ronald Van Heertum, MD2,
  7. Anissa Abi-Dargham, MD1,2 and
  8. Marc Laruelle, MD1,2
  1. 1Department of Psychiatry, Columbia University College of Physicians and Surgeons, and the New York State Psychiatric Institute, New York, New York
  2. 2Department of Radiology, Columbia University College of Physicians and Surgeons, and the New York State Psychiatric Institute, New York, New York
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Journal of Nuclear Medicine: 45 (4)
Journal of Nuclear Medicine
Vol. 45, Issue 4
April 1, 2004
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Comparative Evaluation of Serotonin Transporter Radioligands 11C-DASB and 11C-McN 5652 in Healthy Humans
W. Gordon Frankle, Yiyun Huang, Dah-Ren Hwang, Peter S. Talbot, Mark Slifstein, Ronald Van Heertum, Anissa Abi-Dargham, Marc Laruelle
Journal of Nuclear Medicine Apr 2004, 45 (4) 682-694;

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Comparative Evaluation of Serotonin Transporter Radioligands 11C-DASB and 11C-McN 5652 in Healthy Humans
W. Gordon Frankle, Yiyun Huang, Dah-Ren Hwang, Peter S. Talbot, Mark Slifstein, Ronald Van Heertum, Anissa Abi-Dargham, Marc Laruelle
Journal of Nuclear Medicine Apr 2004, 45 (4) 682-694;
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  • First-in-Human Evaluation of 18F-SynVesT-1, a Radioligand for PET Imaging of Synaptic Vesicle Glycoprotein 2A
  • First-in-Human Assessment of 11C-LSN3172176, an M1 Muscarinic Acetylcholine Receptor PET Radiotracer
  • Kinetic Modeling and Test-Retest Reproducibility of 11C-EKAP and 11C-FEKAP, Novel Agonist Radiotracers for PET Imaging of the {kappa}-Opioid Receptor in Humans
  • First-in-Human Assessment of the Novel PDE2A PET Radiotracer 18F-PF-05270430
  • In Vivo Characterization of a Series of 18F-Diaryl Sulfides (18F-2-(2'-((Dimethylamino)Methyl)-4'-(Fluoroalkoxy)Phenylthio)Benzenamine) for PET Imaging of the Serotonin Transporter
  • Compartmental Modeling of 11C-HOMADAM Binding to the Serotonin Transporter in the Healthy Human Brain
  • Human 5-HT Transporter Availability Predicts Amygdala Reactivity In Vivo
  • Imaging the serotonin transporter during major depressive disorder and antidepressant treatment: 2005 CCNP Young Investigator Award Paper
  • Metabolite Considerations in the In Vivo Quantification of Serotonin Transporters Using 11C-DASB and PET in Humans
  • Estimation of Serotonin Transporter Parameters with 11C-DASB in Healthy Humans: Reproducibility and Comparison of Methods
  • Quantification of 11C-MADAM Binding to the Serotonin Transporter in the Human Brain
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