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Journal of Nuclear Medicine

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OtherClinical Investigations

99mTc-Stannous Colloid White Cell Scintigraphy in Childhood Inflammatory Bowel Disease

Kenneth Peacock, Ute Porn, Robert Howman-Giles, Edward O’Loughlin, Roger Uren, Kevin Gaskin, Stuart Dorney and Ramanand Kamath
Journal of Nuclear Medicine February 2004, 45 (2) 261-265;
Kenneth Peacock
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Ute Porn
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Robert Howman-Giles
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Edward O’Loughlin
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Roger Uren
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Kevin Gaskin
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Stuart Dorney
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Ramanand Kamath
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  • FIGURE 1.
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    FIGURE 1.

    Flow diagram of study population.

  • FIGURE 2.
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    FIGURE 2.

    An 8-y-old girl with Crohn’s disease. (A) Anterior (left) and posterior (right) 3-h planar images. Marked uptake of tracer is present in the distal ileum and in the ascending, transverse, and descending colon. Note the high degree of hepatic uptake, which impairs detection of upper gastrointestinal disease. There is no bladder activity. (B) Coronal 3-h SPECT images. Coronal SPECT more clearly delineates the distal ileal disease.

  • FIGURE 3.
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    FIGURE 3.

    A 13-y-old boy with Crohn’s disease. (A) Anterior (left) and posterior (right) 3-h planar images. Marked uptake of tracer is present throughout the colon, particularly in the distal ileum. (B) Small-bowel series of the terminal ileum. Abnormal separation of bowel loops is seen in the right iliac fossa, with bowel wall thickening. Normal mucosal pattern and terminal ileum peristalsis are present.

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    TABLE 1

    Cross Table of WCS and IBD for All Patients and Endoscopy Patients

    WCSIBD
    PositiveNegativeTotal
    Positive30 (26)3 (2)33 (28)
    Negative4 (4)27 (13)31 (17)
    Total34 (30)30 (15)64 (45)
    • Boldface type = all patients; italic type = endoscopy patients.

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    TABLE 2

    Cross Table for Detection of Terminal Ileum/Proximal Colon IBD by Small-Bowel Series and WCS in Complete-Colonoscopy Patients

    Imaging ofterminalileum/proximalcolonDisease of terminal ileum/proximal colon
    PositiveNegativeTotal
    Positive3 (9)1 (2)4 (11)
    Negative1 (3)1 (4)2 (7)
    Total4 (12)2 (6)6 (18)
    • Boldface type = small-bowel series; italic type = WCS.

    • Note small number of barium studies performed.

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Journal of Nuclear Medicine
Vol. 45, Issue 2
February 1, 2004
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99mTc-Stannous Colloid White Cell Scintigraphy in Childhood Inflammatory Bowel Disease
Kenneth Peacock, Ute Porn, Robert Howman-Giles, Edward O’Loughlin, Roger Uren, Kevin Gaskin, Stuart Dorney, Ramanand Kamath
Journal of Nuclear Medicine Feb 2004, 45 (2) 261-265;

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99mTc-Stannous Colloid White Cell Scintigraphy in Childhood Inflammatory Bowel Disease
Kenneth Peacock, Ute Porn, Robert Howman-Giles, Edward O’Loughlin, Roger Uren, Kevin Gaskin, Stuart Dorney, Ramanand Kamath
Journal of Nuclear Medicine Feb 2004, 45 (2) 261-265;
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