OtherClinical Investigations

123I-Metaiodobenzylguanidine Uptake in the Nape of the Neck of Children: Likely Visualization of Brown Adipose Tissue

Chio Okuyama, Yo Ushijima, Takao Kubota, Toshihide Yoshida, Takako Nakai, Kana Kobayashi and Tsunehiko Nishimura
Journal of Nuclear Medicine September 2003, 44 (9) 1421-1425;

Article Figures & Data

Figures

  • FIGURE 1.
    FIGURE 1.

    123I-MIBG scintigrams (left, anterior image; right, posterior image) of 4-y-old boy who had been treated for neuroblastoma show string-like accumulations on bilateral nape of neck (arrows). Subsequent studies, including CT and tumor markers, failed to detect any evidence of tumors at same site.

  • FIGURE 2.
    FIGURE 2.

    123I-MIBG scintigrams obtained in February (A) and follow-up study obtained in August (B) (same case as in Fig. 1). Accumulation observed in winter (arrows) disappeared in summer. Patient had not undergone any treatment between examinations.

  • FIGURE 3.
    FIGURE 3.

    123I-MIBG scintigrams. (A) Whole-body scan. (B) SPECT sagittal image (upper) and SPECT coronal image (lower) of 2-y-old boy, who had suffered from Horner’s syndrome after operation for tumor originating in thoracic sympathetic nervous trunk. There is laterality in accumulation in chest. SPECT demonstrated apparent nape-of-neck accumulation only on right (healthy) side (arrows).

  • FIGURE 4.
    FIGURE 4.

    123I-MIBG scintigram (A) of 3-y-old girl and her thermogram (B). Distribution of nape-of-neck accumulation resembles distribution of relatively high body temperature (arrows).

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