Article Figures & Data
Figures
- FIGURE 1.
Correlation of percentage of unchanged 11C-FMZ fraction between TLC method and extraction method using plasma samples. Linear regression curve shows y = 0.99x + 0.18. Correlation efficient estimated by Pearson correlation analysis is 0.995.
- FIGURE 2.
Typical time-activity curves after injection of 11C-FMZ. (A) Time-activity curve obtained using whole blood samples and extraction method. +, Radioactivity in whole blood samples (kBq/mL); ○, unmetabolized 11C-FMZ in whole blood samples (kBq/mL). (B) Time-activity curve obtained using plasma samples and extraction method. ×, Radioactivity in plasma samples (kBq/mL); ▵, unmetabolized 11C-FMZ in plasma samples (kBq/mL).
- FIGURE 3.
Time course of percentage of unchanged 11C-FMZ fraction of all subjects. ○, Time course of percentage of unchanged 11C-FMZ fraction obtained from whole blood extraction method; ▵, time course of percentage of unchanged 11C-FMZ fraction obtained from plasma extraction method. Data are presented as mean ± SD.
Tables
- TABLE 1
Comparison of BP Values Using Whole Blood and Plasma and Differences Between BP Calculated Using Whole Blood and BP Calculated Using Plasma
Region BP value* BP value difference† Whole blood Plasma Healthy volunteer number Mean*,‡ 1 2 3 4 5 6 7 8 9 10 11 12 13 Frontal cortex 8.87 ± 1.20 8.85 ± 1.14 −2.35 1.15 0.04 0.56 0.46 −0.63 1.02 −0.04 0.36 1.41 0.46 −0.13 −0.10 0.67 ± 0.67 Parietal cortex 8.58 ± 1.12 8.56 ± 1.07 −2.44 1.08 0.04 0.57 0.41 −0.68 1.07 −0.05 0.36 1.49 0.42 −0.13 −0.10 0.68 ± 0.69 Temp. cortex 9.51 ± 1.10 9.49 ± 1.04 −2.54 1.12 0.02 0.66 0.44 −0.75 1.04 −0.07 0.36 1.79 0.47 −0.13 −0.09 0.73 ± 0.74 Occip. cortex 10.38 ± 1.37 10.35 ± 1.31 −2.44 1.62 0.05 0.50 0.42 −0.64 0.88 −0.04 0.40 1.30 0.50 −0.14 −0.09 0.69 ± 0.71 Basal ganglia 3.31 ± 0.60 3.30 ± 0.57 −0.39 2.25 0.07 0.30 0.22 0.51 0.16 0.10 0.01 1.80 0.12 −0.03 0.02 0.46 ± 0.71 Thalamus 5.01 ± 0.70 5.00 ± 0.68 −0.81 1.06 0.17 0.12 0.20 0.03 0.31 −0.03 0.07 0.82 0.01 −0.04 −0.01 0.28 ± 0.37 Cerebellum 6.00 ± 0.85 5.99 ± 0.83 −1.66 0.75 0.10 0.36 0.29 −0.19 0.60 −0.03 0.16 0.98 0.15 −0.07 −0.06 0.41 ± 0.48 Brain stem 0.84 ± 0.33 0.84 ± 0.33 −0.69 −0.69 0.16 0.45 0.13 −0.60 0.15 −0.08 1.20 0.34 0.19 −0.11 −0.14 0.38 ± 0.33
