Article Figures & Data
Figures
- FIGURE 1.
Left ventricular myocardium is divided into 20 segments, and uptake and washout rates in each section were determined.
- FIGURE 2.
Polar maps of control subject (early image [A] and delayed image [B]) and patient with HCM (early image [C] and delayed image [D]).
- FIGURE 3.
Segment shows maximal early uptake (A) and maximal washout rate (B). Black bars = patients with HCM; white bars = control subjects. Segments shown in Figure 1 are identified as follows: Ap = apical; AS = anteroseptal; AN = anterior; AL = anterolateral; IL = inferolateral; IN = inferior; IS = inferoseptal.
- FIGURE 4.
(A) Relationship between early uptake dispersion and percentage of fractional shortening. (B) Relationship between SD of segmental early uptake and percentage of fractional shortening.
Tables
Characteristic n (%) HCM patients 25 Age (y) 48.5 ± 12.7 Sex Male 19 (76) Female 6 (24) Family history of HCM 16 (64) Family history of SCD 11 (44) History of chest pain 9 (36) History of syncope 2 (8) VT on Holter ECG 4 (16) With obstruction 4 (16) NYHA functional class I 14 (56) II 9 (36) III 2 (8) IV 0 (0) Echocardiogram IVST (mm) 17.8 ± 3.5 PWT (mm) 13.4 ± 3.0 IVST/PWT 1.36 ± 0.31 LAD (mm) 39.1 ± 7.0 LVDd (mm) 47.1 ± 6.7 LVDs (mm) 29.0 ± 7.8 FS (%) 39.0 ± 10.2 SCD = sudden cardiac death; VT = ventricular tachycardia; ECG = electrocardiogram; NYHA = New York Heart Association; IVST = interventricular septal thickness; PWT = posterior wall thickness; LAD = left atrial dimension; LVDd = left ventricular end-diastolic dimension; LVDs = left ventricular end-systolic dimension; FS = fractional shortening.
Parameter HCM Control P H/M Early 1.96 ± 0.22 2.08 ± 0.12 NS Delayed 1.93 ± 0.20 2.17 ± 0.30 0.0077 WR 0.19 ± 0.06 0.09 ± 0.04 <0.0001 Dispersion (%) EU 35.2 ± 9.6 39.2 ± 5.7 NS DU 38.3 ± 7.9 47.9 ± 7.5 0.0024 WR 42.3 ± 17.9 35.2 ± 12.4 NS SD (%) Regional EU 9.9 ± 2.5 11.0 ± 2.0 NS Regional DU 10.8 ± 2.2 14.0 ± 2.5 0.0007 Regional WR 10.8 ± 4.1 9.5 ± 3.0 NS NS = not significant; WR = washout rate; EU = early uptake; DU = delayed uptake.
- TABLE 3
Probability Values and Correlation Coefficients Obtained in Simple Regression Analysis for 123I-MIBG Scintigraphic Variables and Echocardiographic Indices in Patients with HCM
Parameter LVDd LVDs FS P r P r P r H/M Early NS NS NS Delayed 0.0094 −0.509 0.0077 −0.520 0.0373 0.418 WR NS NS NS Dispersion EU 0.0005 0.649 0.0002 0.681 0.0096 −0.507 DU NS NS NS WR 0.0480 0.399 NS NS SD Regional EU 0.0011 0.613 <0.0001 0.729 0.0018 −0.592 Regional DU NS 0.0078 0.520 0.0113 −0.498 Regional WR 0.0310 0.432 NS NS LVDd = left ventricular end-diastolic dimension; LVDs = left ventricular end-systolic dimension; FS = fractional shortening; NS = not significant; WR = washout rate; EU = early uptake; DU = delayed uptake.
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