Symptomatic Prostate-Specific Membrane Antigen PET–Positive Radionecrosis After Multimodality Brain Metastasis–Directed Treatment Including [177Lu]Lu-PSMA-617

Brandon S. Imber; Kenny Kwok Hei Yu; Wassim Abida; Luke R.G. Pike; Milan Grkovski; Thomas J. Kaley; Michael J. Morris; Lisa Bodei; Anton Nosov; Mark P.S. Dunphy; Heiko Schöder; Josef J. Fox; Marc Rosenblum; Tejus Bale; Simone Krebs

doi:10.2967/jnumed.124.269175

Research ArticleThe Illustrated Post

Symptomatic Prostate-Specific Membrane Antigen PET–Positive Radionecrosis After Multimodality Brain Metastasis–Directed Treatment Including [¹⁷⁷Lu]Lu-PSMA-617

Brandon S. Imber, Kenny Kwok Hei Yu, Wassim Abida, Luke R.G. Pike, Milan Grkovski, Thomas J. Kaley, Michael J. Morris, Lisa Bodei, Anton Nosov, Mark P.S. Dunphy, Heiko Schöder, Josef J. Fox, Marc Rosenblum, Tejus Bale and Simone Krebs

Journal of Nuclear Medicine March 2025, jnumed.124.269175; DOI: https://doi.org/10.2967/jnumed.124.269175

Brandon S. Imber

1Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York;

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Kenny Kwok Hei Yu

2Department of Neurosurgery, Memorial Sloan Kettering Cancer Center, New York, New York;

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Wassim Abida

3Department of Medicine, Genitourinary Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York;

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Luke R.G. Pike

1Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York;

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Milan Grkovski

4Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York;

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Thomas J. Kaley

5Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, New York;

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Michael J. Morris

3Department of Medicine, Genitourinary Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York;

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Lisa Bodei

6Department of Radiology, Molecular Imaging, and Therapy Service, Memorial Sloan Kettering Cancer Center, New York, New York;

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Anton Nosov

6Department of Radiology, Molecular Imaging, and Therapy Service, Memorial Sloan Kettering Cancer Center, New York, New York;

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Mark P.S. Dunphy

6Department of Radiology, Molecular Imaging, and Therapy Service, Memorial Sloan Kettering Cancer Center, New York, New York;

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Heiko Schöder

6Department of Radiology, Molecular Imaging, and Therapy Service, Memorial Sloan Kettering Cancer Center, New York, New York;

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Josef J. Fox

6Department of Radiology, Molecular Imaging, and Therapy Service, Memorial Sloan Kettering Cancer Center, New York, New York;

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Marc Rosenblum

7Department of Pathology, Neuropathology Service, Memorial Sloan Kettering Cancer Center, New York, New York; and

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Tejus Bale

7Department of Pathology, Neuropathology Service, Memorial Sloan Kettering Cancer Center, New York, New York; and

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Simone Krebs

6Department of Radiology, Molecular Imaging, and Therapy Service, Memorial Sloan Kettering Cancer Center, New York, New York;

8Department of Nuclear Medicine and Department of Imaging Physics, University of Texas MD Anderson Cancer Center, Houston, Texas

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jnumed.124.269175

DOI

https://doi.org/10.2967/jnumed.124.269175

PubMed

40049744

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Society of Nuclear Medicine

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0161-5505

Online ISSN

2159-662X

History

Received for publication November 18, 2024
Accepted for publication February 20, 2025
Published online March 6, 2025.

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Symptomatic Prostate-Specific Membrane Antigen PET–Positive Radionecrosis After Multimodality Brain Metastasis–Directed Treatment Including [¹⁷⁷Lu]Lu-PSMA-617

Journal of Nuclear Medicine Mar 2025, jnumed.124.269175; DOI: 10.2967/jnumed.124.269175

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Symptomatic Prostate-Specific Membrane Antigen PET–Positive Radionecrosis After Multimodality Brain Metastasis–Directed Treatment Including [¹⁷⁷Lu]Lu-PSMA-617

Journal of Nuclear Medicine Mar 2025, jnumed.124.269175; DOI: 10.2967/jnumed.124.269175

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Symptomatic Prostate-Specific Membrane Antigen PET–Positive Radionecrosis After Multimodality Brain Metastasis–Directed Treatment Including [¹⁷⁷Lu]Lu-PSMA-617

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