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Research ArticleBasic Science Investigation

IL13Rα2-Targeting Antibodies for Immuno-PET in Solid Malignancies

Leah Gajecki, Irina V. Lebedeva, Yu-Rou Liao, Daisy Ambriz, Lukas M. Carter, Melina Kumpf, Samantha Lovibond, Justin S. Hachey, Maya S. Graham, Michael Postow, Jason S. Lewis, David P. Andrew, Manuel Baca, Heiko Schöder, Steven M. Larson, Darren R. Veach and Simone Krebs
Journal of Nuclear Medicine February 2025, jnumed.124.268762; DOI: https://doi.org/10.2967/jnumed.124.268762
Leah Gajecki
1Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York;
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Irina V. Lebedeva
2Sanders Tri-Institutional Therapeutics Discovery Institute, New York, New York;
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Yu-Rou Liao
2Sanders Tri-Institutional Therapeutics Discovery Institute, New York, New York;
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Daisy Ambriz
2Sanders Tri-Institutional Therapeutics Discovery Institute, New York, New York;
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Lukas M. Carter
1Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York;
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Melina Kumpf
1Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York;
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Samantha Lovibond
1Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York;
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Justin S. Hachey
1Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York;
3Department of Pharmacology, Weill Cornell Graduate School of Medicine Sciences, New York, New York;
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Maya S. Graham
4Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, New York;
5Brain Tumor Center, Memorial Sloan Kettering Cancer Center, New York, New York;
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Michael Postow
6Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York;
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Jason S. Lewis
1Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York;
7Radiochemistry and Molecular Imaging Probes Core, Memorial Sloan Kettering Cancer Center, New York, New York;
8Molecular Pharmacology Program, Sloan Kettering Institute, New York, New York;
9Department of Radiology, Weill Cornell Medicine, New York, New York;
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David P. Andrew
2Sanders Tri-Institutional Therapeutics Discovery Institute, New York, New York;
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Manuel Baca
2Sanders Tri-Institutional Therapeutics Discovery Institute, New York, New York;
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Heiko Schöder
1Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York;
9Department of Radiology, Weill Cornell Medicine, New York, New York;
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Steven M. Larson
1Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York;
8Molecular Pharmacology Program, Sloan Kettering Institute, New York, New York;
9Department of Radiology, Weill Cornell Medicine, New York, New York;
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Darren R. Veach
1Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York;
9Department of Radiology, Weill Cornell Medicine, New York, New York;
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Simone Krebs
1Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York;
9Department of Radiology, Weill Cornell Medicine, New York, New York;
10Department of Nuclear Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas; and
11Department of Imaging Physics, University of Texas MD Anderson Cancer Center, Houston, Texas
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Article Information

jnumed.124.268762
DOI 
https://doi.org/10.2967/jnumed.124.268762
PubMed 
39978817

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication September 7, 2024
  • Accepted for publication January 15, 2025
  • Published online February 20, 2025.

Article Versions

  • You are currently viewing a previous version of this article (February 20, 2025 - 08:20).
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Copyright & Usage 
© 2025 by the Society of Nuclear Medicine and Molecular Imaging.

Author Information

  1. Leah Gajecki1,
  2. Irina V. Lebedeva2,
  3. Yu-Rou Liao2,
  4. Daisy Ambriz2,
  5. Lukas M. Carter1,
  6. Melina Kumpf1,
  7. Samantha Lovibond1,
  8. Justin S. Hachey1,3,
  9. Maya S. Graham4,5,
  10. Michael Postow6,
  11. Jason S. Lewis1,7,8,9,
  12. David P. Andrew2,
  13. Manuel Baca2,
  14. Heiko Schöder1,9,
  15. Steven M. Larson1,8,9,
  16. Darren R. Veach1,9 and
  17. Simone Krebs1,9,10,11
  1. 1Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York;
  2. 2Sanders Tri-Institutional Therapeutics Discovery Institute, New York, New York;
  3. 3Department of Pharmacology, Weill Cornell Graduate School of Medicine Sciences, New York, New York;
  4. 4Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, New York;
  5. 5Brain Tumor Center, Memorial Sloan Kettering Cancer Center, New York, New York;
  6. 6Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York;
  7. 7Radiochemistry and Molecular Imaging Probes Core, Memorial Sloan Kettering Cancer Center, New York, New York;
  8. 8Molecular Pharmacology Program, Sloan Kettering Institute, New York, New York;
  9. 9Department of Radiology, Weill Cornell Medicine, New York, New York;
  10. 10Department of Nuclear Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas; and
  11. 11Department of Imaging Physics, University of Texas MD Anderson Cancer Center, Houston, Texas
  1. For correspondence or reprints, contact Simone Krebs (sskrebs{at}mdanderson.org).
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Journal of Nuclear Medicine: 66 (5)
Journal of Nuclear Medicine
Vol. 66, Issue 5
May 1, 2025
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IL13Rα2-Targeting Antibodies for Immuno-PET in Solid Malignancies
Leah Gajecki, Irina V. Lebedeva, Yu-Rou Liao, Daisy Ambriz, Lukas M. Carter, Melina Kumpf, Samantha Lovibond, Justin S. Hachey, Maya S. Graham, Michael Postow, Jason S. Lewis, David P. Andrew, Manuel Baca, Heiko Schöder, Steven M. Larson, Darren R. Veach, Simone Krebs
Journal of Nuclear Medicine Feb 2025, jnumed.124.268762; DOI: 10.2967/jnumed.124.268762

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IL13Rα2-Targeting Antibodies for Immuno-PET in Solid Malignancies
Leah Gajecki, Irina V. Lebedeva, Yu-Rou Liao, Daisy Ambriz, Lukas M. Carter, Melina Kumpf, Samantha Lovibond, Justin S. Hachey, Maya S. Graham, Michael Postow, Jason S. Lewis, David P. Andrew, Manuel Baca, Heiko Schöder, Steven M. Larson, Darren R. Veach, Simone Krebs
Journal of Nuclear Medicine Feb 2025, jnumed.124.268762; DOI: 10.2967/jnumed.124.268762
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