Evaluation of Surgical Margins with Intraoperative PSMA PET/CT and Their Prognostic Value in Radical Prostatectomy

Alexandros Moraitis; Theresa Kahl; Jens Kandziora; Walter Jentzen; David Kersting; Lukas Püllen; Henning Reis; Jens Köllermann; Claudia Kesch; Ulrich Krafft; Boris A. Hadaschik; Habib Zaidi; Ken Herrmann; Francesco Barbato; Wolfgang P. Fendler; Christopher Darr; Pedro Fragoso Costa

doi:10.2967/jnumed.124.268719

Research ArticleClinical Investigation

Evaluation of Surgical Margins with Intraoperative PSMA PET/CT and Their Prognostic Value in Radical Prostatectomy

Alexandros Moraitis, Theresa Kahl, Jens Kandziora, Walter Jentzen, David Kersting, Lukas Püllen, Henning Reis, Jens Köllermann, Claudia Kesch, Ulrich Krafft, Boris A. Hadaschik, Habib Zaidi, Ken Herrmann, Francesco Barbato, Wolfgang P. Fendler, Christopher Darr and Pedro Fragoso Costa

Journal of Nuclear Medicine February 2025, jnumed.124.268719; DOI: https://doi.org/10.2967/jnumed.124.268719

Alexandros Moraitis

1Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany;

2German Cancer Consortium, Partner Site University Hospital Essen, Essen, Germany;

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Theresa Kahl

2German Cancer Consortium, Partner Site University Hospital Essen, Essen, Germany;

3Department of Urology, University Hospital Essen, Essen, Germany;

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Jens Kandziora

1Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany;

2German Cancer Consortium, Partner Site University Hospital Essen, Essen, Germany;

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Walter Jentzen

1Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany;

2German Cancer Consortium, Partner Site University Hospital Essen, Essen, Germany;

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David Kersting

1Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany;

2German Cancer Consortium, Partner Site University Hospital Essen, Essen, Germany;

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Lukas Püllen

2German Cancer Consortium, Partner Site University Hospital Essen, Essen, Germany;

3Department of Urology, University Hospital Essen, Essen, Germany;

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Henning Reis

4Dr. Senckenberg Institute of Pathology, University Hospital Frankfurt, Frankfurt, Germany; and

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Jens Köllermann

4Dr. Senckenberg Institute of Pathology, University Hospital Frankfurt, Frankfurt, Germany; and

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Claudia Kesch

2German Cancer Consortium, Partner Site University Hospital Essen, Essen, Germany;

3Department of Urology, University Hospital Essen, Essen, Germany;

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Ulrich Krafft

2German Cancer Consortium, Partner Site University Hospital Essen, Essen, Germany;

3Department of Urology, University Hospital Essen, Essen, Germany;

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Boris A. Hadaschik

2German Cancer Consortium, Partner Site University Hospital Essen, Essen, Germany;

3Department of Urology, University Hospital Essen, Essen, Germany;

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Habib Zaidi

5Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, Geneva, Switzerland

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Ken Herrmann

1Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany;

2German Cancer Consortium, Partner Site University Hospital Essen, Essen, Germany;

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Francesco Barbato

1Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany;

2German Cancer Consortium, Partner Site University Hospital Essen, Essen, Germany;

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Wolfgang P. Fendler

1Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany;

2German Cancer Consortium, Partner Site University Hospital Essen, Essen, Germany;

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Christopher Darr

2German Cancer Consortium, Partner Site University Hospital Essen, Essen, Germany;

3Department of Urology, University Hospital Essen, Essen, Germany;

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Pedro Fragoso Costa

1Department of Nuclear Medicine, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany;

2German Cancer Consortium, Partner Site University Hospital Essen, Essen, Germany;

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Vol. 66, Issue 5

May 1, 2025

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Evaluation of Surgical Margins with Intraoperative PSMA PET/CT and Their Prognostic Value in Radical Prostatectomy

Journal of Nuclear Medicine Feb 2025, jnumed.124.268719; DOI: 10.2967/jnumed.124.268719

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Evaluation of Surgical Margins with Intraoperative PSMA PET/CT and Their Prognostic Value in Radical Prostatectomy

Journal of Nuclear Medicine Feb 2025, jnumed.124.268719; DOI: 10.2967/jnumed.124.268719

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Keywords

margin assessment
PET/CT
prostate cancer
radical prostatectomy
radioguided surgery

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