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Research ArticleClinical Investigation

Initial Experience with [177Lu]Lu-PSMA-617 After Regulatory Approval for Metastatic Castration-Resistant Prostate Cancer: Efficacy, Safety, and Outcome Prediction

Andrei Gafita, Andrew Voter, Somya Shesadri, Avery Spitz, Catherine H. Marshall, Steven P. Rowe, Mark C. Markwoski, Martin G. Pomper, A. Cahid Civelek, Michael A. Carducci, Samuel R. Denmeade, Jeffrey Young, Kenneth J. Pienta, Channing J. Paller and Lilja B. Solnes
Journal of Nuclear Medicine September 2024, jnumed.124.267723; DOI: https://doi.org/10.2967/jnumed.124.267723
Andrei Gafita
1Division of Nuclear Medicine and Molecular Imaging, Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University, Baltimore, Maryland;
2Johns Hopkins Theranostics Center, Baltimore, Maryland;
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Andrew Voter
1Division of Nuclear Medicine and Molecular Imaging, Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University, Baltimore, Maryland;
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Somya Shesadri
1Division of Nuclear Medicine and Molecular Imaging, Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University, Baltimore, Maryland;
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Avery Spitz
1Division of Nuclear Medicine and Molecular Imaging, Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University, Baltimore, Maryland;
2Johns Hopkins Theranostics Center, Baltimore, Maryland;
3Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland; and
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Catherine H. Marshall
3Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland; and
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Steven P. Rowe
1Division of Nuclear Medicine and Molecular Imaging, Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University, Baltimore, Maryland;
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Mark C. Markwoski
3Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland; and
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Martin G. Pomper
1Division of Nuclear Medicine and Molecular Imaging, Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University, Baltimore, Maryland;
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A. Cahid Civelek
1Division of Nuclear Medicine and Molecular Imaging, Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University, Baltimore, Maryland;
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Michael A. Carducci
3Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland; and
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Samuel R. Denmeade
3Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland; and
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Jeffrey Young
1Division of Nuclear Medicine and Molecular Imaging, Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University, Baltimore, Maryland;
2Johns Hopkins Theranostics Center, Baltimore, Maryland;
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Kenneth J. Pienta
4Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins University, Baltimore, Maryland
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Channing J. Paller
3Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland; and
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Lilja B. Solnes
1Division of Nuclear Medicine and Molecular Imaging, Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University, Baltimore, Maryland;
2Johns Hopkins Theranostics Center, Baltimore, Maryland;
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Article Information

jnumed.124.267723
DOI 
https://doi.org/10.2967/jnumed.124.267723
PubMed 
39299783

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication March 4, 2024
  • Accepted for publication August 7, 2024
  • Published online September 19, 2024.

Article Versions

  • You are currently viewing a previous version of this article (September 19, 2024 - 06:38).
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Copyright & Usage 
© 2024 by the Society of Nuclear Medicine and Molecular Imaging.

Author Information

  1. Andrei Gafita1,2,
  2. Andrew Voter1,
  3. Somya Shesadri1,
  4. Avery Spitz1,2,3,
  5. Catherine H. Marshall3,
  6. Steven P. Rowe1,
  7. Mark C. Markwoski3,
  8. Martin G. Pomper1,
  9. A. Cahid Civelek1,
  10. Michael A. Carducci3,
  11. Samuel R. Denmeade3,
  12. Jeffrey Young1,2,
  13. Kenneth J. Pienta4,
  14. Channing J. Paller*,3 and
  15. Lilja B. Solnes*,1,2
  1. 1Division of Nuclear Medicine and Molecular Imaging, Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University, Baltimore, Maryland;
  2. 2Johns Hopkins Theranostics Center, Baltimore, Maryland;
  3. 3Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland; and
  4. 4Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins University, Baltimore, Maryland
  1. For correspondence or reprints, contact Andrei Gafita (agafita1{at}jhmi.edu).
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  • Toxicities of radioligand and radioisotope therapy in prostate cancer: a systematic review and meta-analysis
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Journal of Nuclear Medicine: 66 (5)
Journal of Nuclear Medicine
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Initial Experience with [177Lu]Lu-PSMA-617 After Regulatory Approval for Metastatic Castration-Resistant Prostate Cancer: Efficacy, Safety, and Outcome Prediction
Andrei Gafita, Andrew Voter, Somya Shesadri, Avery Spitz, Catherine H. Marshall, Steven P. Rowe, Mark C. Markwoski, Martin G. Pomper, A. Cahid Civelek, Michael A. Carducci, Samuel R. Denmeade, Jeffrey Young, Kenneth J. Pienta, Channing J. Paller, Lilja B. Solnes
Journal of Nuclear Medicine Sep 2024, jnumed.124.267723; DOI: 10.2967/jnumed.124.267723

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Initial Experience with [177Lu]Lu-PSMA-617 After Regulatory Approval for Metastatic Castration-Resistant Prostate Cancer: Efficacy, Safety, and Outcome Prediction
Andrei Gafita, Andrew Voter, Somya Shesadri, Avery Spitz, Catherine H. Marshall, Steven P. Rowe, Mark C. Markwoski, Martin G. Pomper, A. Cahid Civelek, Michael A. Carducci, Samuel R. Denmeade, Jeffrey Young, Kenneth J. Pienta, Channing J. Paller, Lilja B. Solnes
Journal of Nuclear Medicine Sep 2024, jnumed.124.267723; DOI: 10.2967/jnumed.124.267723
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