Molecular Imaging of p53 in Mouse Models of Cancer Using a Radiolabeled Antibody TAT Conjugate with SPECT

Hudson Alakonya; Sofia Koustoulidou; Samantha L. Hopkins; Mathew Veal; Javier Ajenjo; Deborah Sneddon; Gemma Dias; Michael Mosley; Julia Baguña Torres; Francesca Amoroso; Amanda Anderson; Alison H. Banham; Bart Cornelissen

doi:10.2967/jnumed.124.267736

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Molecular Imaging of p53 in Mouse Models of Cancer Using a Radiolabeled Antibody TAT Conjugate with SPECT

Hudson Alakonya, Sofia Koustoulidou, Samantha L. Hopkins, Mathew Veal, Javier Ajenjo, Deborah Sneddon, Gemma Dias, Michael Mosley, Julia Baguña Torres, Francesca Amoroso, Amanda Anderson, Alison H. Banham and Bart Cornelissen

Journal of Nuclear Medicine September 2024, jnumed.124.267736; DOI: https://doi.org/10.2967/jnumed.124.267736

Hudson Alakonya

1Department of Oncology, Oxford Institute for Radiation Oncology, University of Oxford, Oxford, United Kingdom;

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Sofia Koustoulidou

1Department of Oncology, Oxford Institute for Radiation Oncology, University of Oxford, Oxford, United Kingdom;

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Samantha L. Hopkins

1Department of Oncology, Oxford Institute for Radiation Oncology, University of Oxford, Oxford, United Kingdom;

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Mathew Veal

1Department of Oncology, Oxford Institute for Radiation Oncology, University of Oxford, Oxford, United Kingdom;

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Javier Ajenjo

1Department of Oncology, Oxford Institute for Radiation Oncology, University of Oxford, Oxford, United Kingdom;

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Deborah Sneddon

1Department of Oncology, Oxford Institute for Radiation Oncology, University of Oxford, Oxford, United Kingdom;

2Department of Chemistry, University of Oxford, Oxford, United Kingdom;

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Gemma Dias

1Department of Oncology, Oxford Institute for Radiation Oncology, University of Oxford, Oxford, United Kingdom;

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Michael Mosley

1Department of Oncology, Oxford Institute for Radiation Oncology, University of Oxford, Oxford, United Kingdom;

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Julia Baguña Torres

1Department of Oncology, Oxford Institute for Radiation Oncology, University of Oxford, Oxford, United Kingdom;

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Francesca Amoroso

1Department of Oncology, Oxford Institute for Radiation Oncology, University of Oxford, Oxford, United Kingdom;

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Amanda Anderson

3Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom; and

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Alison H. Banham

3Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom; and

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Bart Cornelissen

1Department of Oncology, Oxford Institute for Radiation Oncology, University of Oxford, Oxford, United Kingdom;

4Nuclear Medicine and Molecular Imaging, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands

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Journal of Nuclear Medicine

Vol. 66, Issue 5

May 1, 2025

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Molecular Imaging of p53 in Mouse Models of Cancer Using a Radiolabeled Antibody TAT Conjugate with SPECT

Journal of Nuclear Medicine Sep 2024, jnumed.124.267736; DOI: 10.2967/jnumed.124.267736

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Molecular Imaging of p53 in Mouse Models of Cancer Using a Radiolabeled Antibody TAT Conjugate with SPECT

Journal of Nuclear Medicine Sep 2024, jnumed.124.267736; DOI: 10.2967/jnumed.124.267736

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Keywords

molecular imaging
p53
cancer
pancreatic ductal adenocarcinoma

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