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Research ArticleClinical Investigation

Diagnostic Potential of Supplemental Static and Dynamic 68Ga-FAPI-46 PET for Primary 18F-FDG–Negative Pulmonary Lesions

Manuel Röhrich, Johanna Daum, Ewgenija Gutjahr, Anna-Maria Spektor, Frederik M. Glatting, Yasemin Aylin Sahin, Hans Georg Buchholz, Jorge Hoppner, Cathrin Schroeter, Eleni Mavriopoulou, Kai Schlamp, Matthias Grott, Florian Eichhorn, Claus Peter Heußel, Hans Ulrich Kauczor, Michael Kreuter, Frederik Giesel, Mathias Schreckenberger, Hauke Winter and Uwe Haberkorn
Journal of Nuclear Medicine April 2024, jnumed.123.267103; DOI: https://doi.org/10.2967/jnumed.123.267103
Manuel Röhrich
1Department of Nuclear Medicine, University Hospital Heidelberg, Heidelberg, Germany;
2Department of Nuclear Medicine, University Hospital Mainz, Mainz, Germany;
3German Center of Lung Research, Heidelberg, Germany;
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Johanna Daum
1Department of Nuclear Medicine, University Hospital Heidelberg, Heidelberg, Germany;
3German Center of Lung Research, Heidelberg, Germany;
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Ewgenija Gutjahr
4Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany;
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Anna-Maria Spektor
1Department of Nuclear Medicine, University Hospital Heidelberg, Heidelberg, Germany;
3German Center of Lung Research, Heidelberg, Germany;
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Frederik M. Glatting
1Department of Nuclear Medicine, University Hospital Heidelberg, Heidelberg, Germany;
5Clinical Cooperation Unit Molecular and Radiation Oncology, German Cancer Research Center, Heidelberg, Germany;
6Department of Radiation Oncology, University Hospital Heidelberg, Heidelberg, Germany;
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Yasemin Aylin Sahin
2Department of Nuclear Medicine, University Hospital Mainz, Mainz, Germany;
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Hans Georg Buchholz
2Department of Nuclear Medicine, University Hospital Mainz, Mainz, Germany;
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Jorge Hoppner
1Department of Nuclear Medicine, University Hospital Heidelberg, Heidelberg, Germany;
3German Center of Lung Research, Heidelberg, Germany;
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Cathrin Schroeter
1Department of Nuclear Medicine, University Hospital Heidelberg, Heidelberg, Germany;
3German Center of Lung Research, Heidelberg, Germany;
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Eleni Mavriopoulou
1Department of Nuclear Medicine, University Hospital Heidelberg, Heidelberg, Germany;
3German Center of Lung Research, Heidelberg, Germany;
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Kai Schlamp
3German Center of Lung Research, Heidelberg, Germany;
7Department of Radiology, Thoraxklinik, University Hospital Heidelberg, Heidelberg, Germany;
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Matthias Grott
3German Center of Lung Research, Heidelberg, Germany;
8Department of Thoracic Surgery, Thoraxklinik, University Hospital Heidelberg, Heidelberg, Germany;
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Florian Eichhorn
3German Center of Lung Research, Heidelberg, Germany;
8Department of Thoracic Surgery, Thoraxklinik, University Hospital Heidelberg, Heidelberg, Germany;
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Claus Peter Heußel
3German Center of Lung Research, Heidelberg, Germany;
7Department of Radiology, Thoraxklinik, University Hospital Heidelberg, Heidelberg, Germany;
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Hans Ulrich Kauczor
3German Center of Lung Research, Heidelberg, Germany;
9Department of Diagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg, Germany;
10Center for Interstitial and Rare Lung Diseases, Pneumology, and Respiratory Critical Care Medicine, Thoraxklinik, University of Heidelberg, Heidelberg, Germany;
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Michael Kreuter
11Department of Pneumology, Mainz Center for Pulmonary Medicine, Mainz University, Mainz, Germany;
12Medical Center and Department of Pulmonary, Critical Care, and Sleep Medicine, Marienhaus Clinic Mainz, Mainz, Germany;
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Frederik Giesel
1Department of Nuclear Medicine, University Hospital Heidelberg, Heidelberg, Germany;
3German Center of Lung Research, Heidelberg, Germany;
13Department of Nuclear Medicine, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany;
14Institute for Radiation Sciences, Osaka University, Osaka, Japan;
15German Cancer Consortium, Heidelberg, Germany; and
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Mathias Schreckenberger
2Department of Nuclear Medicine, University Hospital Mainz, Mainz, Germany;
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Hauke Winter
3German Center of Lung Research, Heidelberg, Germany;
7Department of Radiology, Thoraxklinik, University Hospital Heidelberg, Heidelberg, Germany;
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Uwe Haberkorn
1Department of Nuclear Medicine, University Hospital Heidelberg, Heidelberg, Germany;
3German Center of Lung Research, Heidelberg, Germany;
9Department of Diagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg, Germany;
16Clinical Cooperation Unit Nuclear Medicine, German Cancer Research Center, Heidelberg, Germany
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Article Information

jnumed.123.267103
DOI 
https://doi.org/10.2967/jnumed.123.267103
PubMed 
38604763

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication November 24, 2023
  • Revision received February 20, 2024
  • Published online April 11, 2024.

Article Versions

  • You are currently viewing a previous version of this article (April 11, 2024 - 09:07).
  • View the most recent version of this article
Copyright & Usage 
© 2024 by the Society of Nuclear Medicine and Molecular Imaging.

Author Information

  1. Manuel Röhrich1,2,3,
  2. Johanna Daum1,3,
  3. Ewgenija Gutjahr4,
  4. Anna-Maria Spektor1,3,
  5. Frederik M. Glatting1,5,6,
  6. Yasemin Aylin Sahin2,
  7. Hans Georg Buchholz2,
  8. Jorge Hoppner1,3,
  9. Cathrin Schroeter1,3,
  10. Eleni Mavriopoulou1,3,
  11. Kai Schlamp3,7,
  12. Matthias Grott3,8,
  13. Florian Eichhorn3,8,
  14. Claus Peter Heußel3,7,
  15. Hans Ulrich Kauczor3,9,10,
  16. Michael Kreuter11,12,
  17. Frederik Giesel1,3,13,14,15,
  18. Mathias Schreckenberger2,
  19. Hauke Winter3,7 and
  20. Uwe Haberkorn1,3,9,16
  1. 1Department of Nuclear Medicine, University Hospital Heidelberg, Heidelberg, Germany;
  2. 2Department of Nuclear Medicine, University Hospital Mainz, Mainz, Germany;
  3. 3German Center of Lung Research, Heidelberg, Germany;
  4. 4Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany;
  5. 5Clinical Cooperation Unit Molecular and Radiation Oncology, German Cancer Research Center, Heidelberg, Germany;
  6. 6Department of Radiation Oncology, University Hospital Heidelberg, Heidelberg, Germany;
  7. 7Department of Radiology, Thoraxklinik, University Hospital Heidelberg, Heidelberg, Germany;
  8. 8Department of Thoracic Surgery, Thoraxklinik, University Hospital Heidelberg, Heidelberg, Germany;
  9. 9Department of Diagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg, Germany;
  10. 10Center for Interstitial and Rare Lung Diseases, Pneumology, and Respiratory Critical Care Medicine, Thoraxklinik, University of Heidelberg, Heidelberg, Germany;
  11. 11Department of Pneumology, Mainz Center for Pulmonary Medicine, Mainz University, Mainz, Germany;
  12. 12Medical Center and Department of Pulmonary, Critical Care, and Sleep Medicine, Marienhaus Clinic Mainz, Mainz, Germany;
  13. 13Department of Nuclear Medicine, Medical Faculty, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany;
  14. 14Institute for Radiation Sciences, Osaka University, Osaka, Japan;
  15. 15German Cancer Consortium, Heidelberg, Germany; and
  16. 16Clinical Cooperation Unit Nuclear Medicine, German Cancer Research Center, Heidelberg, Germany
  1. For correspondence or reprints, contact Manuel Röhrich (manuel.roehrich{at}med.uni-heidelberg.de).
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Diagnostic Potential of Supplemental Static and Dynamic 68Ga-FAPI-46 PET for Primary 18F-FDG–Negative Pulmonary Lesions
Manuel Röhrich, Johanna Daum, Ewgenija Gutjahr, Anna-Maria Spektor, Frederik M. Glatting, Yasemin Aylin Sahin, Hans Georg Buchholz, Jorge Hoppner, Cathrin Schroeter, Eleni Mavriopoulou, Kai Schlamp, Matthias Grott, Florian Eichhorn, Claus Peter Heußel, Hans Ulrich Kauczor, Michael Kreuter, Frederik Giesel, Mathias Schreckenberger, Hauke Winter, Uwe Haberkorn
Journal of Nuclear Medicine Apr 2024, jnumed.123.267103; DOI: 10.2967/jnumed.123.267103

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Diagnostic Potential of Supplemental Static and Dynamic 68Ga-FAPI-46 PET for Primary 18F-FDG–Negative Pulmonary Lesions
Manuel Röhrich, Johanna Daum, Ewgenija Gutjahr, Anna-Maria Spektor, Frederik M. Glatting, Yasemin Aylin Sahin, Hans Georg Buchholz, Jorge Hoppner, Cathrin Schroeter, Eleni Mavriopoulou, Kai Schlamp, Matthias Grott, Florian Eichhorn, Claus Peter Heußel, Hans Ulrich Kauczor, Michael Kreuter, Frederik Giesel, Mathias Schreckenberger, Hauke Winter, Uwe Haberkorn
Journal of Nuclear Medicine Apr 2024, jnumed.123.267103; DOI: 10.2967/jnumed.123.267103
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