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Journal of Nuclear Medicine

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Research ArticleClinical Investigation
Open Access

Specific Uptake in the Bone Marrow Causes High Absorbed Red Marrow Doses During [177Lu]Lu-DOTATATE Treatment

Jens Hemmingsson, Johanna Svensson, Andreas Hallqvist, Katja Smits, Viktor Johanson and Peter Bernhardt
Journal of Nuclear Medicine June 2023, jnumed.123.265484; DOI: https://doi.org/10.2967/jnumed.123.265484
Jens Hemmingsson
1Department of Medical Radiation Sciences, Institute of Clinical Sciences, Sahlgrenska Academy, Gothenburg, Sweden;
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Johanna Svensson
2Department of Oncology, Institute of Clinical Sciences, Sahlgrenska Academy, Gothenburg, Sweden;
3Department of Oncology, Sahlgrenska University Hospital, Gothenburg, Sweden;
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Andreas Hallqvist
2Department of Oncology, Institute of Clinical Sciences, Sahlgrenska Academy, Gothenburg, Sweden;
3Department of Oncology, Sahlgrenska University Hospital, Gothenburg, Sweden;
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Katja Smits
1Department of Medical Radiation Sciences, Institute of Clinical Sciences, Sahlgrenska Academy, Gothenburg, Sweden;
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Viktor Johanson
4Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, Gothenburg, Sweden; and
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Peter Bernhardt
1Department of Medical Radiation Sciences, Institute of Clinical Sciences, Sahlgrenska Academy, Gothenburg, Sweden;
5Department of Medical Physics and Medical Bioengineering, Sahlgrenska University Hospital, Gothenburg, Sweden
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Journal of Nuclear Medicine: 66 (5)
Journal of Nuclear Medicine
Vol. 66, Issue 5
May 1, 2025
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Specific Uptake in the Bone Marrow Causes High Absorbed Red Marrow Doses During [177Lu]Lu-DOTATATE Treatment
Jens Hemmingsson, Johanna Svensson, Andreas Hallqvist, Katja Smits, Viktor Johanson, Peter Bernhardt
Journal of Nuclear Medicine Jun 2023, jnumed.123.265484; DOI: 10.2967/jnumed.123.265484

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Specific Uptake in the Bone Marrow Causes High Absorbed Red Marrow Doses During [177Lu]Lu-DOTATATE Treatment
Jens Hemmingsson, Johanna Svensson, Andreas Hallqvist, Katja Smits, Viktor Johanson, Peter Bernhardt
Journal of Nuclear Medicine Jun 2023, jnumed.123.265484; DOI: 10.2967/jnumed.123.265484
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Cited By...

  • Comparison of the tolerability of 161Tb- and 177Lu-labeled somatostatin analogues in the preclinical setting
  • SPECT/CT Image-Derived Absorbed Dose to Red Marrow Correlates with Hematologic Toxicity in Patients Treated with [177Lu]Lu-DOTATATE
  • Radiolabeled Somatostatin Receptor Antagonist Versus Agonist for Peptide Receptor Radionuclide Therapy in Patients with Therapy-Resistant Meningioma: PROMENADE Phase 0 Study
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Keywords

  • dosimetry
  • red marrow
  • 177Lu
  • SPECT
  • DOTATATE
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