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OtherBasic Science (Animal or Phantoms)

18F-Fluciclovine PET Imaging of Glutaminase Inhibition in Breast Cancer Models

Rong Zhou, Hoon Choi, Jianbo Cao, Austin Pantel, Mamta Gupta, Hsiaoju Lee and David Mankoff
Journal of Nuclear Medicine June 2022, jnumed.122.264152; DOI: https://doi.org/10.2967/jnumed.122.264152
Rong Zhou
University of Pennsylvania, United States
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Hoon Choi
University of Pennsylvania, United States
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Jianbo Cao
University of Pennsylvania, United States
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Austin Pantel
University of Pennsylvania, United States
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Mamta Gupta
University of Pennsylvania, United States
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Hsiaoju Lee
University of Pennsylvania, United States
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David Mankoff
University of Pennsylvania, United States
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Article Information

jnumed.122.264152
DOI 
https://doi.org/10.2967/jnumed.122.264152
PubMed 
35772960

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Published online June 30, 2022.

Article Versions

  • You are currently viewing a previous version of this article (June 30, 2022 - 12:12).
  • View the most recent version of this article
Copyright & Usage 
Copyright © 2022 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

Author Information

  1. Rong Zhou,
  2. Hoon Choi,
  3. Jianbo Cao,
  4. Austin Pantel,
  5. Mamta Gupta,
  6. Hsiaoju Lee and
  7. David Mankoff
  1. University of Pennsylvania, United States
  1. For correspondence or reprints contact: Rong Zhou, University of Pennsylvania, Department of Radiology, Philadelphia, Pennsylvania 19104, United States. E-mail: rongzhou@pennmedicine.upenn.edu

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    Frontiers in Endocrinology 2023 14
  • Management of Advanced Prostate Cancer in the Precision Oncology Era
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  • Disruption of redox balance in glutaminolytic triple negative breast cancer by inhibition of glutaminase and glutamate export
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  • Metformin combined with CB-839 specifically inhibits KRAS-mutant ovarian cancer
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Journal of Nuclear Medicine: 66 (5)
Journal of Nuclear Medicine
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May 1, 2025
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18F-Fluciclovine PET Imaging of Glutaminase Inhibition in Breast Cancer Models
Rong Zhou, Hoon Choi, Jianbo Cao, Austin Pantel, Mamta Gupta, Hsiaoju Lee, David Mankoff
Journal of Nuclear Medicine Jun 2022, jnumed.122.264152; DOI: 10.2967/jnumed.122.264152

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18F-Fluciclovine PET Imaging of Glutaminase Inhibition in Breast Cancer Models
Rong Zhou, Hoon Choi, Jianbo Cao, Austin Pantel, Mamta Gupta, Hsiaoju Lee, David Mankoff
Journal of Nuclear Medicine Jun 2022, jnumed.122.264152; DOI: 10.2967/jnumed.122.264152
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  • Disruption of redox balance in glutaminolytic triple negative breast cancer by inhibition of glutamate export and glutaminase
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Keywords

  • Animal Imaging
  • Oncology: Breast
  • PET
  • 18F-fluciclovine PET
  • CB839
  • distribution volume
  • glutaminase
  • Triple negative breast cancer
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