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Journal of Nuclear Medicine

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OtherBasic Science (Animal or Phantoms)
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Nanobody nuclear imaging allows noninvasive quantification of LAG-3 expression by tumor-infiltrating leukocytes and predicts response of immune checkpoint blockade

Quentin Lecocq, Robin Maximilian Awad, Yannick De Vlaeminck, Wout De Mey, Thomas Ertveldt, Cleo Goyvaerts, Geert Raes, Kris Thielemans, Marleen Keyaerts, Nick Devoogdt and Karine Breckpot
Journal of Nuclear Medicine March 2021, jnumed.120.258871; DOI: https://doi.org/10.2967/jnumed.120.258871
Quentin Lecocq
1 Vrije universiteit brussel, Belgium;
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Robin Maximilian Awad
2 Vrije Universiteit Brussel;
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Yannick De Vlaeminck
2 Vrije Universiteit Brussel;
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Wout De Mey
2 Vrije Universiteit Brussel;
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Thomas Ertveldt
2 Vrije Universiteit Brussel;
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Cleo Goyvaerts
2 Vrije Universiteit Brussel;
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Geert Raes
2 Vrije Universiteit Brussel;
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Kris Thielemans
2 Vrije Universiteit Brussel;
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Marleen Keyaerts
3 UZ Brussel
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Nick Devoogdt
2 Vrije Universiteit Brussel;
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Karine Breckpot
1 Vrije universiteit brussel, Belgium;
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Journal of Nuclear Medicine: 66 (6)
Journal of Nuclear Medicine
Vol. 66, Issue 6
June 1, 2025
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Nanobody nuclear imaging allows noninvasive quantification of LAG-3 expression by tumor-infiltrating leukocytes and predicts response of immune checkpoint blockade
Quentin Lecocq, Robin Maximilian Awad, Yannick De Vlaeminck, Wout De Mey, Thomas Ertveldt, Cleo Goyvaerts, Geert Raes, Kris Thielemans, Marleen Keyaerts, Nick Devoogdt, Karine Breckpot
Journal of Nuclear Medicine Mar 2021, jnumed.120.258871; DOI: 10.2967/jnumed.120.258871

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Nanobody nuclear imaging allows noninvasive quantification of LAG-3 expression by tumor-infiltrating leukocytes and predicts response of immune checkpoint blockade
Quentin Lecocq, Robin Maximilian Awad, Yannick De Vlaeminck, Wout De Mey, Thomas Ertveldt, Cleo Goyvaerts, Geert Raes, Kris Thielemans, Marleen Keyaerts, Nick Devoogdt, Karine Breckpot
Journal of Nuclear Medicine Mar 2021, jnumed.120.258871; DOI: 10.2967/jnumed.120.258871
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Keywords

  • Animal Imaging
  • Radioimmunoimaging
  • SPECT/CT
  • cancer
  • immune checkpoint LAG-3
  • Nanobody
  • nuclear imaging
  • single domain antibody
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