First-in-Human Trial of Dasatinib-Derivative Tracer for Tumor Kinase-Targeted Positron Emission Tomography

Simone Krebs; Darren R Veach; Lukas M Carter; Milan Grkovski; Monica Fornier; Michael J Mauro; Martin H Voss; Daniel C Danila; Eva Burnazi; Manda Null; Kevin Staton; Christina Pressl; Bradley Jay Beattie; Pat B. Zanzonico; Wolfgang Andreas Weber; Serge K. Lyashchenko; Jason S. Lewis; Steven M. Larson; Mark P.S. Dunphy

doi:10.2967/jnumed.119.234864

OtherClinical Investigations (Human)

First-in-Human Trial of Dasatinib-Derivative Tracer for Tumor Kinase-Targeted Positron Emission Tomography

Simone Krebs, Darren R Veach, Lukas M Carter, Milan Grkovski, Monica Fornier, Michael J Mauro, Martin H Voss, Daniel C Danila, Eva Burnazi, Manda Null, Kevin Staton, Christina Pressl, Bradley Jay Beattie, Pat B. Zanzonico, Wolfgang Andreas Weber, Serge K. Lyashchenko, Jason S. Lewis, Steven M. Larson and Mark P.S. Dunphy

Journal of Nuclear Medicine March 2020, jnumed.119.234864; DOI: https://doi.org/10.2967/jnumed.119.234864

Simone Krebs

1 Memorial Sloan Kettering Cancer Center, United States;

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Darren R Veach

1 Memorial Sloan Kettering Cancer Center, United States;

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Lukas M Carter

1 Memorial Sloan Kettering Cancer Center, United States;

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Milan Grkovski

1 Memorial Sloan Kettering Cancer Center, United States;

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Monica Fornier

1 Memorial Sloan Kettering Cancer Center, United States;

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Michael J Mauro

1 Memorial Sloan Kettering Cancer Center, United States;

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Martin H Voss

1 Memorial Sloan Kettering Cancer Center, United States;

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Daniel C Danila

1 Memorial Sloan Kettering Cancer Center, United States;

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Eva Burnazi

1 Memorial Sloan Kettering Cancer Center, United States;

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Manda Null

1 Memorial Sloan Kettering Cancer Center, United States;

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Kevin Staton

1 Memorial Sloan Kettering Cancer Center, United States;

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Christina Pressl

2 The Rockefeller University;

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Bradley Jay Beattie

1 Memorial Sloan Kettering Cancer Center, United States;

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Pat B. Zanzonico

3 Memorial Sloan-Kettering Cancer Center;

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Wolfgang Andreas Weber

4 Technical University of Munich

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Serge K. Lyashchenko

1 Memorial Sloan Kettering Cancer Center, United States;

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Jason S. Lewis

3 Memorial Sloan-Kettering Cancer Center;

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Steven M. Larson

3 Memorial Sloan-Kettering Cancer Center;

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Mark P.S. Dunphy

1 Memorial Sloan Kettering Cancer Center, United States;

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Vol. 66, Issue 5

May 1, 2025

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First-in-Human Trial of Dasatinib-Derivative Tracer for Tumor Kinase-Targeted Positron Emission Tomography

Journal of Nuclear Medicine Mar 2020, jnumed.119.234864; DOI: 10.2967/jnumed.119.234864

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First-in-Human Trial of Dasatinib-Derivative Tracer for Tumor Kinase-Targeted Positron Emission Tomography

Journal of Nuclear Medicine Mar 2020, jnumed.119.234864; DOI: 10.2967/jnumed.119.234864

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Keywords

Molecular imaging
Oncology: General
radiopharmaceuticals
18F-SKI-249380
Dasatinib
PET imaging
Src kinase

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