Differential expression of glucose transporters and hexokinases in prostate cancer with a neuroendocrine gene signature: a mechanistic perspective for FDG imaging of PSMA-suppressed tumors

Martin K. Bakht; Jessica M. Lovnicki; Janice Tubman; Keith F. Stringer; Jonathan Chiaramonte; Michael R. Reynolds; Iulian Derecichei; Rosa-Maria Ferraiuolo; Bre-Anne Fifield; Dorota Lubanska; So Won Oh; Gi Jeong Cheon; Cheol Kwak; Chang Wook Jeong; Keon Wook Kang; John F. Trant; Colm Morrissey; Ilsa Coleman; Yuzhuo Wang; Hojjat Ahmadzadehfar; Xuesen Dong; Lisa A. Porter

doi:10.2967/jnumed.119.231068

OtherTheranostics

Differential expression of glucose transporters and hexokinases in prostate cancer with a neuroendocrine gene signature: a mechanistic perspective for FDG imaging of PSMA-suppressed tumors

Martin K. Bakht, Jessica M. Lovnicki, Janice Tubman, Keith F. Stringer, Jonathan Chiaramonte, Michael R. Reynolds, Iulian Derecichei, Rosa-Maria Ferraiuolo, Bre-Anne Fifield, Dorota Lubanska, So Won Oh, Gi Jeong Cheon, Cheol Kwak, Chang Wook Jeong, Keon Wook Kang, John F. Trant, Colm Morrissey, Ilsa Coleman, Yuzhuo Wang, Hojjat Ahmadzadehfar, Xuesen Dong and Lisa A. Porter

Journal of Nuclear Medicine December 2019, jnumed.119.231068; DOI: https://doi.org/10.2967/jnumed.119.231068

Martin K. Bakht

1 Department of Biomedical Sciences, University of Windsor, Canada;

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Jessica M. Lovnicki

2 Vancouver Prostate Centre, Department of Urologic Sciences, University of British Columbia, Canada;

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Janice Tubman

1 Department of Biomedical Sciences, University of Windsor, Canada;

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Keith F. Stringer

3 Department of Pathology, Cincinnati Children's Hospital Medical Center, United States;

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Jonathan Chiaramonte

4 Department of Chemistry and Biochemistry, University of Windsor, Canada;

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Michael R. Reynolds

4 Department of Chemistry and Biochemistry, University of Windsor, Canada;

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Iulian Derecichei

1 Department of Biomedical Sciences, University of Windsor, Canada;

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Rosa-Maria Ferraiuolo

5 Wayne State school of Medicine and Barbara Ann Karmanos Cancer Institute, United States;

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Bre-Anne Fifield

1 Department of Biomedical Sciences, University of Windsor, Canada;

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Dorota Lubanska

1 Department of Biomedical Sciences, University of Windsor, Canada;

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So Won Oh

6 Seoul National University College of Medicine, Korea, Republic of;

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Gi Jeong Cheon

7 Department of Nuclear Medicine, Seoul National University College of Medicine, Korea, Republic of;

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Cheol Kwak

6 Seoul National University College of Medicine, Korea, Republic of;

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Chang Wook Jeong

6 Seoul National University College of Medicine, Korea, Republic of;

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Keon Wook Kang

6 Seoul National University College of Medicine, Korea, Republic of;

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John F. Trant

4 Department of Chemistry and Biochemistry, University of Windsor, Canada;

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Colm Morrissey

8 Department of Urology, University of Washington, United States;

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Ilsa Coleman

9 Fred Hutchinson Cancer Research Center, Canada;

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Yuzhuo Wang

2 Vancouver Prostate Centre, Department of Urologic Sciences, University of British Columbia, Canada;

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Hojjat Ahmadzadehfar

10 University Hospital Bonn, Germany

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Xuesen Dong

2 Vancouver Prostate Centre, Department of Urologic Sciences, University of British Columbia, Canada;

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Lisa A. Porter

1 Department of Biomedical Sciences, University of Windsor, Canada;

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Differential expression of glucose transporters and hexokinases in prostate cancer with a neuroendocrine gene signature: a mechanistic perspective for FDG imaging of PSMA-suppressed tumors

Journal of Nuclear Medicine Dec 2019, jnumed.119.231068; DOI: 10.2967/jnumed.119.231068

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Differential expression of glucose transporters and hexokinases in prostate cancer with a neuroendocrine gene signature: a mechanistic perspective for FDG imaging of PSMA-suppressed tumors

Journal of Nuclear Medicine Dec 2019, jnumed.119.231068; DOI: 10.2967/jnumed.119.231068

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Keywords

Genitourinary
Molecular Biology
Molecular imaging
neuroendocrine prostate cancer
PSMA
glucokinase
glucose transporters
hexokinases

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Differential expression of glucose transporters and hexokinases in prostate cancer with a neuroendocrine gene signature: a mechanistic perspective for FDG imaging of PSMA-suppressed tumors

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