Evaluation of dosimetry, quantitative methods and test-retest variability of 18F-PI-2620 PET for the assessment of tau deposits in the human brain

Santiago Bullich; Olivier Barret; Cristian Constantinescu; Christine Sandiego; Andre Mueller; Mathias Berndt; Caroline Papin; Audrey Perrotin; Norman Koglin; Heiko Kroth; Andrea Pfeifer; Gilles Tamagnan; Jennifer Madonia; John P Seibyl; Kenneth Marek; Susan de Santi; Ludger M Dinkelborg; Andrew W Stephens

doi:10.2967/jnumed.119.236240

OtherClinical Investigations (Human)

Evaluation of dosimetry, quantitative methods and test-retest variability of ¹⁸F-PI-2620 PET for the assessment of tau deposits in the human brain

Santiago Bullich, Olivier Barret, Cristian Constantinescu, Christine Sandiego, Andre Mueller, Mathias Berndt, Caroline Papin, Audrey Perrotin, Norman Koglin, Heiko Kroth, Andrea Pfeifer, Gilles Tamagnan, Jennifer Madonia, John P Seibyl, Kenneth Marek, Susan de Santi, Ludger M Dinkelborg and Andrew W Stephens

Journal of Nuclear Medicine November 2019, jnumed.119.236240; DOI: https://doi.org/10.2967/jnumed.119.236240

Santiago Bullich

1 Life Molecular Imaging GmbH, Germany;

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Olivier Barret

2 Invicro, United States;

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Cristian Constantinescu

2 Invicro, United States;

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Christine Sandiego

2 Invicro, United States;

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Andre Mueller

1 Life Molecular Imaging GmbH, Germany;

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Mathias Berndt

1 Life Molecular Imaging GmbH, Germany;

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Caroline Papin

1 Life Molecular Imaging GmbH, Germany;

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Audrey Perrotin

1 Life Molecular Imaging GmbH, Germany;

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Norman Koglin

3 Life Molecular Imaging GmbH, Germany;

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Heiko Kroth

4 AC Immune SA, Switzerland;

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Andrea Pfeifer

4 AC Immune SA, Switzerland;

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Gilles Tamagnan

2 Invicro, United States;

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Jennifer Madonia

2 Invicro, United States;

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John P Seibyl

2 Invicro, United States;

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Kenneth Marek

2 Invicro, United States;

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Susan de Santi

5 Life Molecular Imaging Inc, United States

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Ludger M Dinkelborg

1 Life Molecular Imaging GmbH, Germany;

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Andrew W Stephens

1 Life Molecular Imaging GmbH, Germany;

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June 1, 2025

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Evaluation of dosimetry, quantitative methods and test-retest variability of ¹⁸F-PI-2620 PET for the assessment of tau deposits in the human brain

Journal of Nuclear Medicine Nov 2019, jnumed.119.236240; DOI: 10.2967/jnumed.119.236240

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Evaluation of dosimetry, quantitative methods and test-retest variability of ¹⁸F-PI-2620 PET for the assessment of tau deposits in the human brain

Journal of Nuclear Medicine Nov 2019, jnumed.119.236240; DOI: 10.2967/jnumed.119.236240

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Keywords

Neurology
radiobiology/dosimetry
radiotracer tissue kinetics
PET
PI-2620
tau
dosimetry
test-retest

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Evaluation of dosimetry, quantitative methods and test-retest variability of ¹⁸F-PI-2620 PET for the assessment of tau deposits in the human brain

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