Journal of Nuclear Medicine: 66 (1)

January 1, 2025; Volume 66,Issue 1

This Month in JNM

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This Month in JNM
Journal of Nuclear Medicine January 1, 2025, 66 (1) 6A;

Discussions with Leaders

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Solving Challenging Puzzles
Heather Jacene and Johannes Czernin

Journal of Nuclear Medicine January 1, 2025, 66 (1) 1-3; DOI: https://doi.org/10.2967/jnumed.124.269029

The State of the Art

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Nuclear Cardiology Surrogate Biomarkers in Clinical Trials
Robert J.H. Miller, Krishna K. Patel, Jacek Kwiecinski, Leandro Slipczuk, Marc Dweck, David E. Newby, Panithaya Chareonthaitawee and Piotr Slomka

Journal of Nuclear Medicine January 1, 2025, 66 (1) 4-11; DOI: https://doi.org/10.2967/jnumed.124.267869

Hot Topics

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Imaging of the Aging Human Brain
Yan Zhong, Chentao Jin, Xiaofeng Dou, Rui Zhou, Mei Tian and Hong Zhang

Journal of Nuclear Medicine January 1, 2025, 66 (1) 12-13; DOI: https://doi.org/10.2967/jnumed.124.268451

Focus on Molecular Imaging

Open Access
Molecular Imaging of Cancer Stem Cells and Their Role in Therapy Resistance
Sofia N. dos Santos and Timothy H. Witney

Journal of Nuclear Medicine January 1, 2025, 66 (1) 14-19; DOI: https://doi.org/10.2967/jnumed.124.267657

Is It Really Happening?

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Is Routine Dosimetry Really Happening?
John J. Sunderland

Journal of Nuclear Medicine January 1, 2025, 66 (1) 20-23; DOI: https://doi.org/10.2967/jnumed.124.267830

Editorial

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Theranostics for Meningioma on the Rise: New EANM/EANO/RANO/SNMMI Guidelines Pave the Way to Improved Patient Outcomes Using Radiolabeled Somatostatin Receptor Ligands
Nathalie L. Albert, Matthias Preusser, Norbert Galldiks and Jana Ivanidze

Journal of Nuclear Medicine January 1, 2025, 66 (1) 24-25; DOI: https://doi.org/10.2967/jnumed.124.268314

Oncology

Clinical
- PRACTICE STANDARDS
  - Open Access
    SNMMI Procedure Standard/EANM Practice Guideline for Fibroblast Activation Protein (FAP) PET
    Thomas A. Hope, Jeremie Calais, Ajit H. Goenka, Uwe Haberkorn, Mark Konijnenberg, Jonathan McConathy, Daniela E. Oprea-Lager, Laura Trimnal, Elcin Zan, Ken Herrmann and Christophe M. Deroose
    
    Journal of Nuclear Medicine January 1, 2025, 66 (1) 26-33; DOI: https://doi.org/10.2967/jnumed.124.269002
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  [¹⁸F]Fluorthanatrace PET in Ovarian Cancer: Comparison with [¹⁸F]FDG PET, Lesion Location, Tumor Grade, and Breast Cancer Gene Mutation Status
  Joanna K. Weeks, Austin R. Pantel, Sarah B. Gitto, Fang Liu, Erin K. Schubert, Daniel A. Pryma, Michael D. Farwell, David A. Mankoff, Robert H. Mach, Fiona Simpkins and Lilie L. Lin
  
  Journal of Nuclear Medicine January 1, 2025, 66 (1) 34-39; DOI: https://doi.org/10.2967/jnumed.124.267627
Basic
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  Preclinical Evaluation and Pilot Clinical Study of CD137 PET Radiotracer for Noninvasive Monitoring Early Responses of Immunotherapy
  Kai Cheng, Luna Ge, Miaomiao Song, Wanhu Li, Jinsong Zheng, Jingru Liu, Yuxi Luo, Pengfei Sun, Shengnan Xu, Zhen Cheng, Jinming Yu and Jie Liu
  
  Journal of Nuclear Medicine January 1, 2025, 66 (1) 40-46; DOI: https://doi.org/10.2967/jnumed.124.268068

Theranostics

Clinical
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  PET-Based TheraP Eligibility and Outcomes of VISION-Eligible Patients with Metastatic Castration-Resistant Prostate Cancer Who Received ¹⁷⁷Lu-PSMA-617: Importance of ¹⁸F-FDG–Avid Discordant Findings
  Ridvan Arda Demirci, Alireza Ghodsi, Roman Gulati, Sanaz Behnia, Peter S. Nelson, Heather H. Cheng, Todd A. Yezefski, Michael C. Haffner, Jessica E. Hawley, Robert B. Montgomery, Evan Y. Yu, Michael T. Schweizer, Delphine L. Chen and Amir Iravani
  
  Journal of Nuclear Medicine January 1, 2025, 66 (1) 47-53; DOI: https://doi.org/10.2967/jnumed.124.268167
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  Low- and High-Volume Disease in Metastatic Hormone-Sensitive Prostate Cancer: From CHAARTED to PSMA PET—An International Multicenter Retrospective Study
  Lena M. Unterrainer, Thomas A. Hope, Wolfgang P. Fendler, Tristan Grogan, Honest Ndlovu, Wesley Armstrong, Francesco Barbato, Matthias R. Benz, Matthew B. Rettig, Amar U. Kishan, Mike Sathekge, Ken Herrmann, Johannes Czernin and Jeremie Calais
  
  Journal of Nuclear Medicine January 1, 2025, 66 (1) 54-60; DOI: https://doi.org/10.2967/jnumed.124.268441
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  Real-World Comparison of Cabazitaxel Versus ¹⁷⁷Lu-PSMA Radiopharmaceutical Therapy in Metastatic Castration-Resistant Prostate Cancer
  Mike Wenzel, Florestan Koll, Benedikt Hoeh, Clara Humke, Carolin Siech, Nicolai Mader, Amir Sabet, Daniel Groener, Thomas Steuber, Markus Graefen, Tobias Maurer, Christian Brandts, Severine Banek, Felix K.H. Chun and Philipp Mandel
  
  Journal of Nuclear Medicine January 1, 2025, 66 (1) 61-66; DOI: https://doi.org/10.2967/jnumed.124.268807
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  Pattern of Failure in Patients with Biochemical Recurrence After PSMA Radioguided Surgery
  Lilit Schweiger, Tobias Maurer, Ricarda Simon, Thomas Horn, Matthias Heck, Wolfgang A. Weber, Matthias Eiber and Isabel Rauscher
  
  Journal of Nuclear Medicine January 1, 2025, 66 (1) 67-72; DOI: https://doi.org/10.2967/jnumed.124.268151
- INVITED PERSPECTIVE
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    Perspective on Pattern of Failure in Patients with Biochemical Recurrence After PSMA Radioguided Surgery
    Roberto C. Delgado Bolton
    
    Journal of Nuclear Medicine January 1, 2025, 66 (1) 73-74; DOI: https://doi.org/10.2967/jnumed.124.268783
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  Rates of PSMA PET Staging and Positivity in Newly Diagnosed Prostate Cancer in a National Health Care System
  Sean R. Miller, Rachel Tucker Gonzalez, William C. Jackson, Megan E.V. Caram, Phoebe A. Tsao, Kristian Stensland, Yashesh Shah, Daniel Wale, Ka Kit Wong, Benjamin L. Viglianti, David Elliott, Tanner Caverly, Timothy P. Hofer, Sameer Saini, Michael D. Green, Matthew Schipper, Robert T. Dess and Alex K. Bryant
  
  Journal of Nuclear Medicine January 1, 2025, 66 (1) 75-83; DOI: https://doi.org/10.2967/jnumed.124.268555
Basic
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  Mathematic Modeling of Tumor Growth During [¹⁷⁷Lu]Lu-PSMA Therapy: Insights into Treatment Optimization
  Nouran R.R. Zaid, Remco Bastiaannet, Rob Hobbs and George Sgouros
  
  Journal of Nuclear Medicine January 1, 2025, 66 (1) 84-90; DOI: https://doi.org/10.2967/jnumed.124.268457

Radionuclide Therapy

Open Access
Localized In Vivo Prodrug Activation Using Radionuclides
Jeremy M. Quintana, Fangchao Jiang, Mikyung Kang, Victor Valladolid Onecha, Arda Könik, Lei Qin, Victoria E. Rodriguez, Huiyu Hu, Nicholas Borges, Ishaan Khurana, Leou I. Banla, Mariane Le Fur, Peter Caravan, Jan Schuemann, Alejandro Bertolet, Ralph Weissleder, Miles A. Miller and Thomas S.C. Ng

Journal of Nuclear Medicine January 1, 2025, 66 (1) 91-97; DOI: https://doi.org/10.2967/jnumed.124.268559

Cardiovascular

Clinical
- FEATURED ARTICLE OF THE MONTH
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    Targeting Fibroblast Activation Protein for Molecular Imaging of Fibrotic Remodeling in Pulmonary Arterial Hypertension
    Peng Hou, Haiming Chen, Sihao Liang, Wenliang Guo, Ruiyue Zhao, Huailu Pan, Haimin Liu, Youcai Li, Jie Lv, Kaixiang Zhong, Miao Ke, Yimin Fu, Huizhen Zhong, Xinlu Wang and Cheng Hong
    
    Journal of Nuclear Medicine January 1, 2025, 66 (1) 98-103; DOI: https://doi.org/10.2967/jnumed.124.268376

Pulmonary

Clinical
- Open Access
  Comparability of Quantifying Relative Lung Ventilation with Inhaled ^99mTc-Technegas and ¹³³Xe in Patients Undergoing Evaluation for Lung Transplantation
  Ashwin Singh Parihar, Joyce C. Mhlanga, Henry D. Royal and Barry A. Siegel
  
  Journal of Nuclear Medicine January 1, 2025, 66 (1) 104-109; DOI: https://doi.org/10.2967/jnumed.124.268801

Neurology

Clinical
- Open Access
  Quantification Supports Amyloid PET Visual Assessment of Challenging Cases: Results from the AMYPAD Diagnostic and Patient Management Study
  Lyduine E. Collij, Gérard N. Bischof, Daniele Altomare, Ilse Bader, Mark Battle, David Vállez García, Isadora Lopes Alves, Robin Wolz, Rossella Gismondi, Andrew Stephens, Zuzana Walker, Philip Scheltens, Agneta Nordberg, Juan Domingo Gispert, Alexander Drzezga, Andrés Perissinotti, Silvia Morbelli, Christopher Buckley, Valentina Garibotto, Giovanni B. Frisoni, Gill Farrar and Frederik Barkhof; on behalf of the AMYPAD Consortium
  
  Journal of Nuclear Medicine January 1, 2025, 66 (1) 110-116; DOI: https://doi.org/10.2967/jnumed.124.268119
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  [¹¹C]PS13 Demonstrates Pharmacologically Selective and Substantial Binding to Cyclooxygenase-1 in the Human Brain
  Nafiseh Ghazanfari, Jeih-San Liow, Min-Jeong Kim, Raven Cureton, Adrian Lee, Carson Knoer, Madeline Jenkins, Jinsoo Hong, Jose A. Montero Santamaria, H. Umesha Shetty, Anthony Galassi, Paul Wighton, Martin Nørgaard, Douglas N. Greve, Sami S. Zoghbi, Victor W. Pike, Robert B. Innis and Paolo Zanotti-Fregonara
  
  Journal of Nuclear Medicine January 1, 2025, 66 (1) 117-122; DOI: https://doi.org/10.2967/jnumed.124.267928
Basic
- FEATURED BASIC SCIENCE ARTICLE
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    Comparison Between Brain and Cerebellar Autoradiography Using [¹⁸F]Flortaucipir, [¹⁸F]MK6240, and [¹⁸F]PI2620 in Postmortem Human Brain Tissue
    Antonio Aliaga, Joseph Therriault, Kely Monica Quispialaya, Arturo Aliaga, Robert Hopewell, Nesrine Rahmouni, Arthur C. Macedo, Peter Kunach, Jean-Paul Soucy, Gassan Massarweh, Aida Abreu Diaz, Tharick A. Pascoal, Andreia Rocha, Marie-Christine Guiot, Luiza S. Machado, Marco Antônio De Bastiani, Débora Guerini de Souza, Diogo O. Souza, Serge Gauthier, Eduardo R. Zimmer and Pedro Rosa-Neto
    
    Journal of Nuclear Medicine January 1, 2025, 66 (1) 123-129; DOI: https://doi.org/10.2967/jnumed.124.267539
- Open Access
  Antibody-Based PET Imaging of Misfolded Superoxide Dismutase 1 in an Amyotrophic Lateral Sclerosis Mouse Model
  Jacques A. Rousseau, Marcel Maier, Samia Ait-Mohand, Véronique Dumulon-Perreault, Otman Sarrhini, Sébastien Tremblay, Etienne Rousseau, Michael Salzmann and Brigitte Guérin
  
  Journal of Nuclear Medicine January 1, 2025, 66 (1) 130-135; DOI: https://doi.org/10.2967/jnumed.124.268343
Translational
- Open Access
  Myelin Imaging of the Spinal Cord in Animal Models and Patients with Multiple Sclerosis Using [¹¹C]MeDAS PET: A Translational Study
  Chris W.J. van der Weijden, Ahmed K.M.A. Ahmed, Anouk van der Hoorn, Junqing Zhu, Chunying Wu, Yanming Wang, Gilles N. Stormezand, Rudi A.J.O. Dierckx, Jan F. Meilof and Erik F.J. de Vries
  
  Journal of Nuclear Medicine January 1, 2025, 66 (1) 136-141; DOI: https://doi.org/10.2967/jnumed.123.266896
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  Effect of Acute Hypoxia Exposure on the Availability of A₁ Adenosine Receptors and Perfusion in the Human Brain
  Manuel Michno, Jan Schmitz, Anna L. Foerges, Simone Beer, Jens Jordan, Bernd Neumaier, Alexander Drzezga, Daniel Aeschbach, Andreas Bauer, Jens Tank, Henning Weis, Eva-Maria Elmenhorst and David Elmenhorst
  
  Journal of Nuclear Medicine January 1, 2025, 66 (1) 142-149; DOI: https://doi.org/10.2967/jnumed.124.268455

Physics and Instrumentation

Clinical
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  Quantitative Accuracy Assessment of the NeuroEXPLORER for Diverse Imaging Applications: Moving Beyond Standard Evaluations
  Negar Omidvari, Ekaterina Shanina, Edwin K. Leung, Xishan Sun, Yusheng Li, Tim Mulnix, Paul Gravel, Shannan Henry, David Matuskey, Tommaso Volpi, Terry Jones, Ramsey D. Badawi, Hongdi Li, Richard E. Carson, Jinyi Qi and Simon R. Cherry
  
  Journal of Nuclear Medicine January 1, 2025, 66 (1) 150-157; DOI: https://doi.org/10.2967/jnumed.124.268309

Highlights

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2024 SNMMI Highlights Lecture: General Clinical Specialties
Twyla Bartel

Journal of Nuclear Medicine January 1, 2025, 66 (1) 158-161; DOI: https://doi.org/10.2967/jnumed.124.269263

The Illustrated Post

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Meningioma Revisited: Should Whole-Body Staging with [⁶⁸Ga]Ga-DOTATOC PET/CT of High-Grade Meningiomas Become Standard Practice?
Ekin Ermiş, Nicolas Bachmann, Katharina Lutz and Thomas Pyka

Journal of Nuclear Medicine January 1, 2025, 66 (1) 162; DOI: https://doi.org/10.2967/jnumed.124.267934

Departments

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Erratum
Journal of Nuclear Medicine January 1, 2025, 66 (1) 149;

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Table of Contents

This Month in JNM

Discussions with Leaders

The State of the Art

Hot Topics

Focus on Molecular Imaging

Is It Really Happening?

Editorial

Oncology

Clinical

PRACTICE STANDARDS

Basic

Theranostics

Clinical

INVITED PERSPECTIVE

Basic

Radionuclide Therapy

Cardiovascular

Clinical

FEATURED ARTICLE OF THE MONTH

Pulmonary

Clinical

Neurology

Clinical

Basic

FEATURED BASIC SCIENCE ARTICLE

Translational

Physics and Instrumentation

Clinical

Highlights

The Illustrated Post

Departments

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