[⁶⁸Ga]Ga-PSMA-11 PET/CT–Positive Hepatic Inflammatory Pseudotumor: Possible PSMA-Avid Pitfall in Nuclear Imaging

(A) Maximum-intensity projection image showing increased [⁶⁸Ga]Ga-PSMA-11 uptake (arrowhead) in liver (SUV_max, 11.3). (B–E) Gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid MRI showing nodule in segment 5 (arrow) hyperintense in T2-weighted image (B), highly hyperintense in diffusion-weighted image (C), highly hyperintense in arterial phase (D), and with targetoid sign in transitional phase (E). (F) Axial-fused [⁶⁸Ga]Ga-PSMA-11 PET/CT showing increased PSMA uptake (SUV_max, 11.3) at segment 5. (G) PSMA immunohistochemistry image (×20) with sparce positive endothelial cells in intralesional microvascular component (circles) and negative inflammatory cells. (H) Negative PSMA immunofluorescence image (×10) in normal liver parenchyma (asterisk) with adjacent inflammatory infiltrate and sparce but strongly positive endothelial cells in intralesional microvascular component (circles).