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Research ArticleClinical Investigation

Reproducibility and Accuracy of the PRIMARY Score on PSMA PET and of PI-RADS on Multiparametric MRI for Prostate Cancer Diagnosis Within a Real-World Database

Louise Emmett, Nathan Papa, William Counter, Jeremie Calais, Francesco Barbato, Irene Burger, Matthias Eiber, Matthew J. Roberts, Shikha Agrawal, Anthony Franklin, Alan Xue, Krishan Rasiah, Nikeith John, Daniel Moon, Mark Frydenberg, John Yaxley, Phillip Stricker, Keith Wong, Geoff Coughlin, Troy Gianduzzo, Boon Kua, Bao Ho, Andrew Nguyen, Victor Liu, Jonathan Lee, Edward Hsiao, Tom Sutherland, Elisa Perry, Wolfgang P. Fendler and Thomas A. Hope
Journal of Nuclear Medicine January 2024, 65 (1) 94-99; DOI: https://doi.org/10.2967/jnumed.123.266164
Louise Emmett
1Department of Theranostics and Nuclear Medicine, St. Vincent’s Hospital Sydney, Sydney, New South Wales, Australia;
2Garvan Institute of Medical Research, Sydney, New South Wales, Australia;
3St. Vincent’s Clinical School, University of New South Wales, Sydney, New South Wales, Australia;
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Nathan Papa
2Garvan Institute of Medical Research, Sydney, New South Wales, Australia;
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William Counter
1Department of Theranostics and Nuclear Medicine, St. Vincent’s Hospital Sydney, Sydney, New South Wales, Australia;
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Jeremie Calais
4Ahmanson Translational Theranostics, Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, UCLA, Los Angeles, California;
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Francesco Barbato
5Department of Nuclear Medicine, University of Duisburg–Essen and German Cancer Consortium–University Hospital Essen, Essen, Germany;
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Irene Burger
6Department of Nuclear Medicine, Kantonsspital Baden, Baden, Switzerland;
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Matthias Eiber
7Department of Nuclear Medicine, School of Medicine, Technical University Munich, Munich, Germany;
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Matthew J. Roberts
8Department of Urology, Royal Brisbane and Women’s Hospital, Brisbane, Queensland, Australia;
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Shikha Agrawal
1Department of Theranostics and Nuclear Medicine, St. Vincent’s Hospital Sydney, Sydney, New South Wales, Australia;
2Garvan Institute of Medical Research, Sydney, New South Wales, Australia;
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Anthony Franklin
8Department of Urology, Royal Brisbane and Women’s Hospital, Brisbane, Queensland, Australia;
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Alan Xue
9Department of Surgery, Faculty of Medicine, Monash University, Melbourne, Victoria, Australia;
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Krishan Rasiah
10Department of Urology, Royal North Shore Hospital, Sydney, New South Wales, Australia;
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Nikeith John
1Department of Theranostics and Nuclear Medicine, St. Vincent’s Hospital Sydney, Sydney, New South Wales, Australia;
3St. Vincent’s Clinical School, University of New South Wales, Sydney, New South Wales, Australia;
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Daniel Moon
11Division of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia;
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Mark Frydenberg
9Department of Surgery, Faculty of Medicine, Monash University, Melbourne, Victoria, Australia;
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John Yaxley
12Wesley Hospital, Brisbane, Queensland, Australia;
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Phillip Stricker
13St. Vincent’s Prostate Cancer Centre, Darlinghurst, New South Wales, Australia;
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Keith Wong
1Department of Theranostics and Nuclear Medicine, St. Vincent’s Hospital Sydney, Sydney, New South Wales, Australia;
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Geoff Coughlin
12Wesley Hospital, Brisbane, Queensland, Australia;
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Troy Gianduzzo
12Wesley Hospital, Brisbane, Queensland, Australia;
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Boon Kua
12Wesley Hospital, Brisbane, Queensland, Australia;
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Bao Ho
1Department of Theranostics and Nuclear Medicine, St. Vincent’s Hospital Sydney, Sydney, New South Wales, Australia;
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Andrew Nguyen
1Department of Theranostics and Nuclear Medicine, St. Vincent’s Hospital Sydney, Sydney, New South Wales, Australia;
3St. Vincent’s Clinical School, University of New South Wales, Sydney, New South Wales, Australia;
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Victor Liu
1Department of Theranostics and Nuclear Medicine, St. Vincent’s Hospital Sydney, Sydney, New South Wales, Australia;
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Jonathan Lee
1Department of Theranostics and Nuclear Medicine, St. Vincent’s Hospital Sydney, Sydney, New South Wales, Australia;
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Edward Hsiao
9Department of Surgery, Faculty of Medicine, Monash University, Melbourne, Victoria, Australia;
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Tom Sutherland
15Department of Radiology, St. Vincent’s Hospital Melbourne, Melbourne, Victoria, Australia; and
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Elisa Perry
15Department of Radiology, St. Vincent’s Hospital Melbourne, Melbourne, Victoria, Australia; and
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Wolfgang P. Fendler
5Department of Nuclear Medicine, University of Duisburg–Essen and German Cancer Consortium–University Hospital Essen, Essen, Germany;
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Thomas A. Hope
16Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California
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Article Information

vol. 65 no. 1 94-99
DOI 
https://doi.org/10.2967/jnumed.123.266164
PubMed 
38050155

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication June 14, 2023
  • Revision received October 4, 2023
  • Published online January 2, 2024.

Article Versions

  • previous version (November 30, 2023 - 08:22).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2024 by the Society of Nuclear Medicine and Molecular Imaging.

Author Information

  1. Louise Emmett1,2,3,
  2. Nathan Papa2,
  3. William Counter1,
  4. Jeremie Calais4,
  5. Francesco Barbato5,
  6. Irene Burger6,
  7. Matthias Eiber7,
  8. Matthew J. Roberts8,
  9. Shikha Agrawal1,2,
  10. Anthony Franklin8,
  11. Alan Xue9,
  12. Krishan Rasiah10,
  13. Nikeith John1,3,
  14. Daniel Moon11,
  15. Mark Frydenberg9,
  16. John Yaxley12,
  17. Phillip Stricker13,
  18. Keith Wong1,
  19. Geoff Coughlin12,
  20. Troy Gianduzzo12,
  21. Boon Kua12,
  22. Bao Ho1,
  23. Andrew Nguyen1,3,
  24. Victor Liu1,
  25. Jonathan Lee1,
  26. Edward Hsiao9,
  27. Tom Sutherland15,
  28. Elisa Perry15,
  29. Wolfgang P. Fendler5 and
  30. Thomas A. Hope16
  1. 1Department of Theranostics and Nuclear Medicine, St. Vincent’s Hospital Sydney, Sydney, New South Wales, Australia;
  2. 2Garvan Institute of Medical Research, Sydney, New South Wales, Australia;
  3. 3St. Vincent’s Clinical School, University of New South Wales, Sydney, New South Wales, Australia;
  4. 4Ahmanson Translational Theranostics, Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, UCLA, Los Angeles, California;
  5. 5Department of Nuclear Medicine, University of Duisburg–Essen and German Cancer Consortium–University Hospital Essen, Essen, Germany;
  6. 6Department of Nuclear Medicine, Kantonsspital Baden, Baden, Switzerland;
  7. 7Department of Nuclear Medicine, School of Medicine, Technical University Munich, Munich, Germany;
  8. 8Department of Urology, Royal Brisbane and Women’s Hospital, Brisbane, Queensland, Australia;
  9. 9Department of Surgery, Faculty of Medicine, Monash University, Melbourne, Victoria, Australia;
  10. 10Department of Urology, Royal North Shore Hospital, Sydney, New South Wales, Australia;
  11. 11Division of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia;
  12. 12Wesley Hospital, Brisbane, Queensland, Australia;
  13. 13St. Vincent’s Prostate Cancer Centre, Darlinghurst, New South Wales, Australia;
  14. 14Department of Nuclear Medicine, Royal North Shore Hospital, Sydney, New South Wales, Australia;
  15. 15Department of Radiology, St. Vincent’s Hospital Melbourne, Melbourne, Victoria, Australia; and
  16. 16Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California
  1. For correspondence or reprints, contact Louise Emmett (louise.emmett{at}svha.org.au).
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Reproducibility and Accuracy of the PRIMARY Score on PSMA PET and of PI-RADS on Multiparametric MRI for Prostate Cancer Diagnosis Within a Real-World Database
Louise Emmett, Nathan Papa, William Counter, Jeremie Calais, Francesco Barbato, Irene Burger, Matthias Eiber, Matthew J. Roberts, Shikha Agrawal, Anthony Franklin, Alan Xue, Krishan Rasiah, Nikeith John, Daniel Moon, Mark Frydenberg, John Yaxley, Phillip Stricker, Keith Wong, Geoff Coughlin, Troy Gianduzzo, Boon Kua, Bao Ho, Andrew Nguyen, Victor Liu, Jonathan Lee, Edward Hsiao, Tom Sutherland, Elisa Perry, Wolfgang P. Fendler, Thomas A. Hope
Journal of Nuclear Medicine Jan 2024, 65 (1) 94-99; DOI: 10.2967/jnumed.123.266164

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Reproducibility and Accuracy of the PRIMARY Score on PSMA PET and of PI-RADS on Multiparametric MRI for Prostate Cancer Diagnosis Within a Real-World Database
Louise Emmett, Nathan Papa, William Counter, Jeremie Calais, Francesco Barbato, Irene Burger, Matthias Eiber, Matthew J. Roberts, Shikha Agrawal, Anthony Franklin, Alan Xue, Krishan Rasiah, Nikeith John, Daniel Moon, Mark Frydenberg, John Yaxley, Phillip Stricker, Keith Wong, Geoff Coughlin, Troy Gianduzzo, Boon Kua, Bao Ho, Andrew Nguyen, Victor Liu, Jonathan Lee, Edward Hsiao, Tom Sutherland, Elisa Perry, Wolfgang P. Fendler, Thomas A. Hope
Journal of Nuclear Medicine Jan 2024, 65 (1) 94-99; DOI: 10.2967/jnumed.123.266164
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Keywords

  • multiparametric MRI
  • PSMA
  • prostate-specific membrane antigen
  • PET
  • prostate cancer
  • diagnosis
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