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Research ArticleClinical Investigation

Clinical Decision Support for Axillary Lymph Node Staging in Newly Diagnosed Breast Cancer Patients Based on 18F-FDG PET/MRI and Machine Learning

Janna Morawitz, Benjamin Sigl, Christian Rubbert, Nils-Martin Bruckmann, Frederic Dietzel, Lena J. Häberle, Saskia Ting, Svjetlana Mohrmann, Eugen Ruckhäberle, Ann-Kathrin Bittner, Oliver Hoffmann, Pascal Baltzer, Panagiotis Kapetas, Thomas Helbich, Paola Clauser, Wolfgang P. Fendler, Christoph Rischpler, Ken Herrmann, Benedikt M. Schaarschmidt, Andreas Stang, Lale Umutlu, Gerald Antoch, Julian Caspers and Julian Kirchner
Journal of Nuclear Medicine February 2023, 64 (2) 304-311; DOI: https://doi.org/10.2967/jnumed.122.264138
Janna Morawitz
1Department of Diagnostic and Interventional Radiology, Medical Faculty, University of Duesseldorf, Duesseldorf, Germany;
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Benjamin Sigl
2Department of Biomedical Imaging and Image-Guided Therapy, Division of General Radiology, Medical University of Vienna, Vienna, Austria;
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Christian Rubbert
1Department of Diagnostic and Interventional Radiology, Medical Faculty, University of Duesseldorf, Duesseldorf, Germany;
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Nils-Martin Bruckmann
1Department of Diagnostic and Interventional Radiology, Medical Faculty, University of Duesseldorf, Duesseldorf, Germany;
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Frederic Dietzel
1Department of Diagnostic and Interventional Radiology, Medical Faculty, University of Duesseldorf, Duesseldorf, Germany;
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Lena J. Häberle
3Institute of Pathology, Medical Faculty, Heinrich Heine University and University Hospital Duesseldorf, Duesseldorf, Germany;
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Saskia Ting
4Institute of Pathology, University Hospital Essen, West German Cancer Center, University of Duisburg–Essen and the German Cancer Consortium (DKTK), Essen, Germany;
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Svjetlana Mohrmann
5Department of Gynecology, University of Duesseldorf, Medical Faculty, Duesseldorf, Germany;
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Eugen Ruckhäberle
5Department of Gynecology, University of Duesseldorf, Medical Faculty, Duesseldorf, Germany;
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Ann-Kathrin Bittner
6Department of Gynecology and Obstetrics, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
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Oliver Hoffmann
6Department of Gynecology and Obstetrics, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
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Pascal Baltzer
2Department of Biomedical Imaging and Image-Guided Therapy, Division of General Radiology, Medical University of Vienna, Vienna, Austria;
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Panagiotis Kapetas
2Department of Biomedical Imaging and Image-Guided Therapy, Division of General Radiology, Medical University of Vienna, Vienna, Austria;
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Thomas Helbich
2Department of Biomedical Imaging and Image-Guided Therapy, Division of General Radiology, Medical University of Vienna, Vienna, Austria;
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Paola Clauser
2Department of Biomedical Imaging and Image-Guided Therapy, Division of General Radiology, Medical University of Vienna, Vienna, Austria;
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Wolfgang P. Fendler
7Department of Nuclear Medicine, University Hospital Essen, University of Duisburg–Essen and German Cancer Consortium (DKTK), Essen, Germany;
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Christoph Rischpler
7Department of Nuclear Medicine, University Hospital Essen, University of Duisburg–Essen and German Cancer Consortium (DKTK), Essen, Germany;
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Ken Herrmann
7Department of Nuclear Medicine, University Hospital Essen, University of Duisburg–Essen and German Cancer Consortium (DKTK), Essen, Germany;
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Benedikt M. Schaarschmidt
8Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, University of Duisburg–Essen, Essen, Germany; and
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Andreas Stang
9Institute of Medical Informatics, Biometry, and Epidemiology, Essen University Medical Center, Essen, Germany
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Lale Umutlu
8Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, University of Duisburg–Essen, Essen, Germany; and
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Gerald Antoch
1Department of Diagnostic and Interventional Radiology, Medical Faculty, University of Duesseldorf, Duesseldorf, Germany;
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Julian Caspers
1Department of Diagnostic and Interventional Radiology, Medical Faculty, University of Duesseldorf, Duesseldorf, Germany;
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Julian Kirchner
1Department of Diagnostic and Interventional Radiology, Medical Faculty, University of Duesseldorf, Duesseldorf, Germany;
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Article Information

vol. 64 no. 2 304-311
DOI 
https://doi.org/10.2967/jnumed.122.264138
PubMed 
36137756

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication March 16, 2022
  • Revision received August 19, 2022
  • Published online February 1, 2023.

Article Versions

  • previous version (September 22, 2022 - 12:25).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2023 by the Society of Nuclear Medicine and Molecular Imaging.

Author Information

  1. Janna Morawitz1,
  2. Benjamin Sigl2,
  3. Christian Rubbert1,
  4. Nils-Martin Bruckmann1,
  5. Frederic Dietzel1,
  6. Lena J. Häberle3,
  7. Saskia Ting4,
  8. Svjetlana Mohrmann5,
  9. Eugen Ruckhäberle5,
  10. Ann-Kathrin Bittner6,
  11. Oliver Hoffmann6,
  12. Pascal Baltzer2,
  13. Panagiotis Kapetas2,
  14. Thomas Helbich2,
  15. Paola Clauser2,
  16. Wolfgang P. Fendler7,
  17. Christoph Rischpler7,
  18. Ken Herrmann7,
  19. Benedikt M. Schaarschmidt8,
  20. Andreas Stang9,
  21. Lale Umutlu8,
  22. Gerald Antoch1,
  23. Julian Caspers*,1 and
  24. Julian Kirchner*,1
  1. 1Department of Diagnostic and Interventional Radiology, Medical Faculty, University of Duesseldorf, Duesseldorf, Germany;
  2. 2Department of Biomedical Imaging and Image-Guided Therapy, Division of General Radiology, Medical University of Vienna, Vienna, Austria;
  3. 3Institute of Pathology, Medical Faculty, Heinrich Heine University and University Hospital Duesseldorf, Duesseldorf, Germany;
  4. 4Institute of Pathology, University Hospital Essen, West German Cancer Center, University of Duisburg–Essen and the German Cancer Consortium (DKTK), Essen, Germany;
  5. 5Department of Gynecology, University of Duesseldorf, Medical Faculty, Duesseldorf, Germany;
  6. 6Department of Gynecology and Obstetrics, University Hospital Essen, University of Duisburg–Essen, Essen, Germany;
  7. 7Department of Nuclear Medicine, University Hospital Essen, University of Duisburg–Essen and German Cancer Consortium (DKTK), Essen, Germany;
  8. 8Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, University of Duisburg–Essen, Essen, Germany; and
  9. 9Institute of Medical Informatics, Biometry, and Epidemiology, Essen University Medical Center, Essen, Germany
  1. For correspondence or reprints, contact Janna Morawitz (janna.morawitz{at}med.uni-duesseldorf.de).
  1. ↵* Contributed equally to this work.

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Journal of Nuclear Medicine: 64 (2)
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February 1, 2023
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Clinical Decision Support for Axillary Lymph Node Staging in Newly Diagnosed Breast Cancer Patients Based on 18F-FDG PET/MRI and Machine Learning
Janna Morawitz, Benjamin Sigl, Christian Rubbert, Nils-Martin Bruckmann, Frederic Dietzel, Lena J. Häberle, Saskia Ting, Svjetlana Mohrmann, Eugen Ruckhäberle, Ann-Kathrin Bittner, Oliver Hoffmann, Pascal Baltzer, Panagiotis Kapetas, Thomas Helbich, Paola Clauser, Wolfgang P. Fendler, Christoph Rischpler, Ken Herrmann, Benedikt M. Schaarschmidt, Andreas Stang, Lale Umutlu, Gerald Antoch, Julian Caspers, Julian Kirchner
Journal of Nuclear Medicine Feb 2023, 64 (2) 304-311; DOI: 10.2967/jnumed.122.264138

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Clinical Decision Support for Axillary Lymph Node Staging in Newly Diagnosed Breast Cancer Patients Based on 18F-FDG PET/MRI and Machine Learning
Janna Morawitz, Benjamin Sigl, Christian Rubbert, Nils-Martin Bruckmann, Frederic Dietzel, Lena J. Häberle, Saskia Ting, Svjetlana Mohrmann, Eugen Ruckhäberle, Ann-Kathrin Bittner, Oliver Hoffmann, Pascal Baltzer, Panagiotis Kapetas, Thomas Helbich, Paola Clauser, Wolfgang P. Fendler, Christoph Rischpler, Ken Herrmann, Benedikt M. Schaarschmidt, Andreas Stang, Lale Umutlu, Gerald Antoch, Julian Caspers, Julian Kirchner
Journal of Nuclear Medicine Feb 2023, 64 (2) 304-311; DOI: 10.2967/jnumed.122.264138
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Keywords

  • breast cancer
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