Journal of Nuclear Medicine: 64 (2)

February 1, 2023; Volume 64,Issue 2

This Month in JNM

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This Month in JNM
Journal of Nuclear Medicine February 1, 2023, 64 (2) 8A;

Discussions with Leaders

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Advancing Clinical Trial Innovation in Pancreatic Cancer
Diane M. Simeone, Ken Herrmann and Johannes Czernin

Journal of Nuclear Medicine February 1, 2023, 64 (2) 185-187; DOI: https://doi.org/10.2967/jnumed.123.265432

The State of the Art

Open Access
Artificial Intelligence in Nuclear Medicine: Opportunities, Challenges, and Responsibilities Toward a Trustworthy Ecosystem
Babak Saboury, Tyler Bradshaw, Ronald Boellaard, Irène Buvat, Joyita Dutta, Mathieu Hatt, Abhinav K. Jha, Quanzheng Li, Chi Liu, Helena McMeekin, Michael A. Morris, Peter J.H. Scott, Eliot Siegel, John J. Sunderland, Neeta Pandit-Taskar, Richard L. Wahl, Sven Zuehlsdorff and Arman Rahmim

Journal of Nuclear Medicine February 1, 2023, 64 (2) 188-196; DOI: https://doi.org/10.2967/jnumed.121.263703

Hot Topics

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Whole-Body PET Imaging: A Catalyst for Whole-Person Research?
Lalith Kumar Shiyam Sundar, Marcus Hacker and Thomas Beyer

Journal of Nuclear Medicine February 1, 2023, 64 (2) 197-199; DOI: https://doi.org/10.2967/jnumed.122.264555

Issues and Controversies

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Scientific Fraud, Publication Bias, and Honorary Authorship in Nuclear Medicine
Thomas C. Kwee, Maan T. Almaghrabi and Robert M. Kwee

Journal of Nuclear Medicine February 1, 2023, 64 (2) 200-203; DOI: https://doi.org/10.2967/jnumed.122.264679

Procedure Standard

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SNMMI Procedure Standard/EANM Practice Guideline for SSTR PET: Imaging Neuroendocrine Tumors
Thomas A. Hope, Martin Allen-Auerbach, Lisa Bodei, Jeremie Calais, Magnus Dahlbom, Lisa K. Dunnwald, Michael M. Graham, Heather A. Jacene, Courtney Lawhn Heath, Erik S. Mittra, Chadwick L. Wright, Wolfgang P. Fendler, Ken Herrmann, David Taïeb and Andreas Kjaer

Journal of Nuclear Medicine February 1, 2023, 64 (2) 204-210; DOI: https://doi.org/10.2967/jnumed.122.264860

Theranostics

Clinical
- FEATURED ARTICLE OF THE MONTH
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    Survival Outcomes in Metastatic Gastroenteropancreatic Neuroendocrine Tumor Patients Receiving Concomitant ²²⁵Ac-DOTATATE–Targeted α-Therapy and Capecitabine: A Real-World-Scenario Management-Based Long-Term Outcome Study
    Sanjana Ballal, Madhav P. Yadav, Madhavi Tripathi, Ranjit Kumar Sahoo and Chandrasekhar Bal
    
    Journal of Nuclear Medicine February 1, 2023, 64 (2) 211-218; DOI: https://doi.org/10.2967/jnumed.122.264043
- INVITED PERSPECTIVE
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    The Future of Targeted α-Therapy Is Bright, but Rigorous Studies Are Necessary to Advance the Field
    Jonathan Strosberg, Ken Herrmann and Lisa Bodei
    
    Journal of Nuclear Medicine February 1, 2023, 64 (2) 219-220; DOI: https://doi.org/10.2967/jnumed.122.264805
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  Evaluation of ¹⁷⁷Lu-PSMA-617 SPECT/CT Quantitation as a Response Biomarker Within a Prospective ¹⁷⁷Lu-PSMA-617 and NOX66 Combination Trial (LuPIN)
  Sarennya Pathmanandavel, Megan Crumbaker, Bao Ho, Andrew O. Yam, Peter Wilson, Remy Niman, Maria Ayers, Shikha Sharma, Adam Hickey, Peter Eu, Martin Stockler, Andrew J. Martin, Anthony M. Joshua, Andrew Nguyen and Louise Emmett
  
  Journal of Nuclear Medicine February 1, 2023, 64 (2) 221-226; DOI: https://doi.org/10.2967/jnumed.122.264398
- Open Access
  Eligibility for ¹⁷⁷Lu-PSMA Therapy Depends on the Choice of Companion Diagnostic Tracer: A Comparison of ⁶⁸Ga-PSMA-11 and ^99mTc-MIP-1404 in Metastatic Castration-Resistant Prostate Cancer
  Gary J.R. Cook, Wai-Lup Wong, Bal Sanghera, Stephen Mangar, Amarnath Challapalli, Amit Bahl, Paul Bassett, Darren Leaning and Christian Schmidkonz
  
  Journal of Nuclear Medicine February 1, 2023, 64 (2) 227-231; DOI: https://doi.org/10.2967/jnumed.122.264296
Translational
- FEATURED TRANSLATIONAL SCIENCE ARTICLE
  - Open Access
    ⁶⁸Ga-DOTATATE Prepared from Cyclotron-Produced ⁶⁸Ga: An Integrated Solution from Cyclotron Vault to Safety Assessment and Diagnostic Efficacy in Neuroendocrine Cancer Patients
    Sébastien Tremblay, Jean-François Beaudoin, Ophélie Bélissant Benesty, Samia Ait-Mohand, Véronique Dumulon-Perreault, Étienne Rousseau, Éric E. Turcotte and Brigitte Guérin
    
    Journal of Nuclear Medicine February 1, 2023, 64 (2) 232-238; DOI: https://doi.org/10.2967/jnumed.121.263768

Oncology

Clinical
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  Application of the Lugano Classification for Initial Evaluation, Staging, and Response Assessment of Hodgkin and Non-Hodgkin Lymphoma: The PRoLoG Consensus Initiative (Part 2—Technical)
  Fabien Ricard, Sally Barrington, Ron Korn, Guenther Brueggenwerth, Judith Trotman, Bruce Cheson, Gilles Salles, Larry Schwartz, Greg Goldmacher, Rudresh Jarecha, Jayant Narang, Florence Broussais, Paul Galette, Min Liu, Surabhi Bajpai, Eric Perlman, Julie Gillis, Ira Smalberg, Pierre Terve, Gudrun Zahlmann and Annette Schmid
  
  Journal of Nuclear Medicine February 1, 2023, 64 (2) 239-243; DOI: https://doi.org/10.2967/jnumed.122.264124
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  Static and Dynamic ⁶⁸Ga-FAPI PET/CT for the Detection of Malignant Transformation of Intraductal Papillary Mucinous Neoplasia of the Pancreas
  Matthias Lang, Anna-Maria Spektor, Thomas Hielscher, Jorge Hoppner, Frederik M. Glatting, Felix Bicu, Thilo Hackert, Ulrike Heger, Thomas Pausch, Ewgenija Gutjahr, Hendrik Rathke, Frederik L. Giesel, Clemens Kratochwil, Christine Tjaden, Uwe Haberkorn and Manuel Röhrich
  
  Journal of Nuclear Medicine February 1, 2023, 64 (2) 244-251; DOI: https://doi.org/10.2967/jnumed.122.264361
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  Prospective Phase II Trial of [⁶⁸Ga]Ga-NODAGA-E[c(RGDyK)]₂ PET/CT Imaging of Integrin α_vβ₃ for Prognostication in Patients with Neuroendocrine Neoplasms
  Esben Andreas Carlsen, Mathias Loft, Annika Loft, Dorota Czyzewska, Mikkel Andreassen, Seppo W. Langer, Ulrich Knigge and Andreas Kjaer
  
  Journal of Nuclear Medicine February 1, 2023, 64 (2) 252-259; DOI: https://doi.org/10.2967/jnumed.122.264383

Cardiology

Clinical
- Open Access
  Precision of Myocardial Blood Flow and Flow Reserve Measurement During CZT SPECT Perfusion Imaging Processing: Intra- and Interobserver Variability
  Matthieu Bailly, Frédérique Thibault, Gilles Metrard, Maxime Courtehoux, Denis Angoulvant and Maria Joao Ribeiro
  
  Journal of Nuclear Medicine February 1, 2023, 64 (2) 260-265; DOI: https://doi.org/10.2967/jnumed.122.264454

Neurology

Clinical
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  Early-Phase ¹⁸F-Florbetapir and ¹⁸F-Flutemetamol Images as Proxies of Brain Metabolism in a Memory Clinic Setting
  Cecilia Boccalini, Débora Elisa Peretti, Federica Ribaldi, Max Scheffler, Sara Stampacchia, Szymon Tomczyk, Cristelle Rodriguez, Marie-Louise Montandon, Sven Haller, Panteleimon Giannakopoulos, Giovanni B. Frisoni, Daniela Perani and Valentina Garibotto
  
  Journal of Nuclear Medicine February 1, 2023, 64 (2) 266-273; DOI: https://doi.org/10.2967/jnumed.122.264256
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  Differential Effects of Tau Stage, Lewy Body Pathology, and Substantia Nigra Degeneration on ¹⁸F-FDG PET Patterns in Clinical Alzheimer Disease
  Jesús Silva-Rodríguez, Miguel A. Labrador-Espinosa, Alexis Moscoso, Michael Schöll, Pablo Mir, Michel J. Grothe and for the Alzheimer’s Disease Neuroimaging Initiative
  
  Journal of Nuclear Medicine February 1, 2023, 64 (2) 274-280; DOI: https://doi.org/10.2967/jnumed.122.264213
- Open Access
  Longitudinal Tau PET Using ¹⁸F-Flortaucipir: The Effect of Relative Cerebral Blood Flow on Quantitative and Semiquantitative Parameters
  Denise Visser, Hayel Tuncel, Rik Ossenkoppele, Maqsood Yaqub, Emma E. Wolters, Tessa Timmers, Emma Weltings, Emma M. Coomans, Marijke E. den Hollander, Wiesje M. van der Flier, Bart N.M. van Berckel and Sandeep S.V. Golla
  
  Journal of Nuclear Medicine February 1, 2023, 64 (2) 281-286; DOI: https://doi.org/10.2967/jnumed.122.263926
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  Investigating Tau and Amyloid Tracer Skull Binding in Studies of Alzheimer Disease
  Shaney Flores, Charles D. Chen, Yi Su, Aylin Dincer, Sarah J. Keefe, Nicole S. McKay, Angela M. Paulick, Gloria Guzman Perez-Carrillo, Liang Wang, Russ C. Hornbeck, Manu Goyal, Andrei Vlassenko, Sally Schwarz, Michael L. Nickels, Dean F. Wong, Zhude Tu, Jonathan E. McConathy, John C. Morris, Tammie L.S. Benzinger and Brian A. Gordon
  
  Journal of Nuclear Medicine February 1, 2023, 64 (2) 287-293; DOI: https://doi.org/10.2967/jnumed.122.263948
- SPECIAL CONTRIBUTION
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    The RSNA QIBA Profile for Amyloid PET as an Imaging Biomarker for Cerebral Amyloid Quantification
    Anne M. Smith, Nancy A. Obuchowski, Norman L. Foster, Gregory Klein, P. David Mozley, Adriaan A. Lammertsma, Richard L. Wahl, John J. Sunderland, Jean-Luc Vanderheyden, Tammie L.S. Benzinger, Paul E. Kinahan, Dean F. Wong, Eric S. Perlman, Satoshi Minoshima and Dawn Matthews
    
    Journal of Nuclear Medicine February 1, 2023, 64 (2) 294-303; DOI: https://doi.org/10.2967/jnumed.122.264031

AI/Advanced Image Analysis

Clinical
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  Clinical Decision Support for Axillary Lymph Node Staging in Newly Diagnosed Breast Cancer Patients Based on ¹⁸F-FDG PET/MRI and Machine Learning
  Janna Morawitz, Benjamin Sigl, Christian Rubbert, Nils-Martin Bruckmann, Frederic Dietzel, Lena J. Häberle, Saskia Ting, Svjetlana Mohrmann, Eugen Ruckhäberle, Ann-Kathrin Bittner, Oliver Hoffmann, Pascal Baltzer, Panagiotis Kapetas, Thomas Helbich, Paola Clauser, Wolfgang P. Fendler, Christoph Rischpler, Ken Herrmann, Benedikt M. Schaarschmidt, Andreas Stang, Lale Umutlu, Gerald Antoch, Julian Caspers and Julian Kirchner
  
  Journal of Nuclear Medicine February 1, 2023, 64 (2) 304-311; DOI: https://doi.org/10.2967/jnumed.122.264138

Radiobiology/Dosimetry

Clinical
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  Fetal Dose from PET and CT in Pregnant Patients
  Christiane Sarah Burton, Kirk Frey, Frederic Fahey, Mark S. Kaminski, Richard K.J. Brown, Judith M. Pohlen and Barry L. Shulkin
  
  Journal of Nuclear Medicine February 1, 2023, 64 (2) 312-319; DOI: https://doi.org/10.2967/jnumed.122.263959
Translational
- Open Access
  First-in-Humans Evaluation of Safety and Dosimetry of ⁶⁴Cu-LLP2A for PET Imaging
  Richard Laforest, Anchal Ghai, Tyler J. Fraum, Reiko Oyama, Jennifer Frye, Helen Kaemmerer, Greg Gaehle, Tom Voller, Cedric Mpoy, Buck E. Rogers, Mark Fiala, Kooresh I. Shoghi, Samuel Achilefu, Michael Rettig, Ravi Vij, John F. DiPersio, Sally Schwarz, Monica Shokeen and Farrokh Dehdashti
  
  Journal of Nuclear Medicine February 1, 2023, 64 (2) 320-328; DOI: https://doi.org/10.2967/jnumed.122.264349
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  Lesion Quantification Accuracy of Digital ⁹⁰Y PET Imaging in the Context of Dosimetry in Systemic Fibroblast Activation Protein Inhibitor Radionuclide Therapy
  David Kersting, Walter Jentzen, Daniel Jeromin, Ilektra-Antonia Mavroeidi, Maurizio Conti, Florian Büther, Ken Herrmann, Christoph Rischpler, Rainer Hamacher, Wolfgang P. Fendler, Robert Seifert and Pedro Fragoso Costa
  
  Journal of Nuclear Medicine February 1, 2023, 64 (2) 329-336; DOI: https://doi.org/10.2967/jnumed.122.264338

Illustrated Post

Clinical
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  First-in-Humans PET/MRI of In Vivo GD2 Expression in Osteosarcoma
  Nils Florian Trautwein, Gerald Reischl, Christian Seitz, Helmut Dittmann, Ferdinand Seith, Sophia Scheuermann, Tobias Feuchtinger, Frank Dombrowski, Rupert Handgretinger, Jörg Fuchs, Bernd Pichler, Christian la Fougère and Johannes Schwenck
  
  Journal of Nuclear Medicine February 1, 2023, 64 (2) 337-338; DOI: https://doi.org/10.2967/jnumed.122.264626

Letters to the Editor

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Dosimetry in Radiopharmaceutical Therapy
Michael Stabin

Journal of Nuclear Medicine February 1, 2023, 64 (2) 339; DOI: https://doi.org/10.2967/jnumed.122.265056
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Reply: Dosimetry in Radiopharmaceutical Therapy
Joe O’Donoghue, Pat Zanzonico, John Humm and Adam Kesner

Journal of Nuclear Medicine February 1, 2023, 64 (2) 339-340; DOI: https://doi.org/10.2967/jnumed.122.265078

Departments

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Nuclear Medicine: The Essentials
Abass Alavi

Journal of Nuclear Medicine February 1, 2023, 64 (2) 341; DOI: https://doi.org/10.2967/jnumed.122.264788
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In Memoriam
Journal of Nuclear Medicine February 1, 2023, 64 (2) 342;

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Table of Contents

This Month in JNM

Discussions with Leaders

The State of the Art

Hot Topics

Issues and Controversies

Procedure Standard

Theranostics

Clinical

FEATURED ARTICLE OF THE MONTH

INVITED PERSPECTIVE

Translational

FEATURED TRANSLATIONAL SCIENCE ARTICLE

Oncology

Clinical

Cardiology

Clinical

Neurology

Clinical

SPECIAL CONTRIBUTION

AI/Advanced Image Analysis

Clinical

Radiobiology/Dosimetry

Clinical

Translational

Illustrated Post

Clinical

Letters to the Editor

Departments

In this issue

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