Differential Effects of Tau Stage, Lewy Body Pathology, and Substantia Nigra Degeneration on 18F-FDG PET Patterns in Clinical Alzheimer Disease

Jesús Silva-Rodríguez; Miguel A. Labrador-Espinosa; Alexis Moscoso; Michael Schöll; Pablo Mir; Michel J. Grothe; for the Alzheimer’s Disease Neuroimaging Initiative

doi:10.2967/jnumed.122.264213

Research ArticleClinical Investigation

Differential Effects of Tau Stage, Lewy Body Pathology, and Substantia Nigra Degeneration on ¹⁸F-FDG PET Patterns in Clinical Alzheimer Disease

Jesús Silva-Rodríguez, Miguel A. Labrador-Espinosa, Alexis Moscoso, Michael Schöll, Pablo Mir, Michel J. Grothe and for the Alzheimer’s Disease Neuroimaging Initiative

Journal of Nuclear Medicine February 2023, 64 (2) 274-280; DOI: https://doi.org/10.2967/jnumed.122.264213

Jesús Silva-Rodríguez

1Unidad de Trastornos del Movimiento, Servicio de Neurología y Neurofisiología Clínica, Instituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain;

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Miguel A. Labrador-Espinosa

2Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain;

3Departamento de Medicina, Facultad de Medicina, Universidad de Sevilla, Seville, Spain;

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Alexis Moscoso

4Wallenberg Center for Molecular and Translational Medicine and Department of Psychiatry and Neurochemistry, University of Gothenburg, Gothenburg, Sweden; and

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Michael Schöll

4Wallenberg Center for Molecular and Translational Medicine and Department of Psychiatry and Neurochemistry, University of Gothenburg, Gothenburg, Sweden; and

5Dementia Research Centre, Queen Square Institute of Neurology, University College London, London, United Kingdom

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Pablo Mir

2Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain;

3Departamento de Medicina, Facultad de Medicina, Universidad de Sevilla, Seville, Spain;

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Michel J. Grothe

2Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain;

4Wallenberg Center for Molecular and Translational Medicine and Department of Psychiatry and Neurochemistry, University of Gothenburg, Gothenburg, Sweden; and

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Journal of Nuclear Medicine

Vol. 64, Issue 2

February 1, 2023

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Differential Effects of Tau Stage, Lewy Body Pathology, and Substantia Nigra Degeneration on ¹⁸F-FDG PET Patterns in Clinical Alzheimer Disease

Jesús Silva-Rodríguez, Miguel A. Labrador-Espinosa, Alexis Moscoso, Michael Schöll, Pablo Mir, Michel J. Grothe, for the Alzheimer’s Disease Neuroimaging Initiative

Journal of Nuclear Medicine Feb 2023, 64 (2) 274-280; DOI: 10.2967/jnumed.122.264213

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Differential Effects of Tau Stage, Lewy Body Pathology, and Substantia Nigra Degeneration on ¹⁸F-FDG PET Patterns in Clinical Alzheimer Disease

Jesús Silva-Rodríguez, Miguel A. Labrador-Espinosa, Alexis Moscoso, Michael Schöll, Pablo Mir, Michel J. Grothe, for the Alzheimer’s Disease Neuroimaging Initiative

Journal of Nuclear Medicine Feb 2023, 64 (2) 274-280; DOI: 10.2967/jnumed.122.264213

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18F-FDG
LBD
AD
autopsy

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Differential Effects of Tau Stage, Lewy Body Pathology, and Substantia Nigra Degeneration on ¹⁸F-FDG PET Patterns in Clinical Alzheimer Disease

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