Article Figures & Data
Figures
- FIGURE 1.
Box plots of 99mTc-MIP-1404 and 68Ga-PSMA-11 liver SUVmax (P = 0.002) (A) and lesion-to-liver SUVmax ratios (P = 0.009) (B) in patients with mCRPC. median = central line; mean = X; box = interquartile range (IQR); whiskers = maximum and minimum values; O = outliers > 1.5 IQR.
Tables
Characteristic 99mTc-MIP-1404 68Ga-PSMA-11 Median age (y) 72 (range, 62–91) 71 (range, 54–84) Median Gleason score 9 (SD, 8–9) 9 (SD, 7–9) Mean PSA 413.6 (SD, 581.6) 415.6 (SD, 1,101.7) Prior ADT 24 25 Current ADT 6 8 Prior prostatectomy 14 4 Prior prostate radiotherapy 13 13 Prior chemotherapy 20 15 miTNM Prostate 7 10 N1 8 13 M1a 8 8 M1b 23 23 M1c 3 4 ADT = androgen deprivation therapy; miTNM = molecular imaging tumor, node and metastasis staging.
- TABLE 2.
Lesion, Normal-Organ (Liver, Spleen, Parotid Gland, MBP), and Lesion–to–Normal-Organ Ratios Between 99mTc-MIP-1404 and 68Ga-PSMA-11 mCRPC Patients
99mTc-MIP-1404 68Ga-PSMA-11 Parameter Median Mean ± SD Median Mean ± SD P Lesion SUVmax 18.2 (4.1–52.1) 17.3 (3.4–128.0) 0.93 Liver SUVmax 8.5 (4.7–13.9) 5.8 (3.9–9.0) 0.002 Lesion-to-liver SUVmax ratio 2.5 (0.6–10.0) 3.7 (0.8–17.1) 0.009 Parotid gland SUVmax 13.4 ± 7.1 16.8 ± 6.4 0.23 Lesion–to–parotid gland SUVmax ratio 1.8 (0.3–6.4) 1.4 (0.3–7.0) 0.5 Spleen SUVmax 11.5 (5.4–22.5) 9.3 (4.9–16.0) 0.072 Lesion-to-spleen SUVmax ratio 1.4 (0.3–6.1) 2.0 (0.4–14.9) 0.034 MBP SUVmax 1.1 ± 0.3 1.6 ± 0.3 0.003 Lesion-to-MBP SUVmax ratio 19.9 (3.8–114.5) 13.5 (2.7–57.6) 0.011 Data in parentheses are ranges.
