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Research ArticleFEATURED TRANSLATIONAL SCIENCE ARTICLE

PET Imaging of System xC− in Immune Cells for Assessment of Disease Activity in Mice and Patients with Inflammatory Bowel Disease

Minjung Seo, Yeji Kim, Byong Duk Ye, Sang Hyoung Park, Seog-Young Kim, Jin Hwa Jung, Sung Wook Hwang, Sun Young Chae, Dong Yun Lee, Sang Ju Lee, Seung Jun Oh, Jihun Kim, Ji Young Kim, Sae Jung Na, Misung Kim, Sang-Yeob Kim, Norman Koglin, Andrew W. Stephens, Mi-Na Kweon and Dae Hyuk Moon
Journal of Nuclear Medicine October 2022, 63 (10) 1586-1591; DOI: https://doi.org/10.2967/jnumed.121.263289
Minjung Seo
1Department of Nuclear Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Republic of Korea;
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Yeji Kim
2Department of Convergence Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea;
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Byong Duk Ye
3Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea;
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Sang Hyoung Park
3Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea;
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Seog-Young Kim
2Department of Convergence Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea;
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Jin Hwa Jung
2Department of Convergence Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea;
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Sung Wook Hwang
3Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea;
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Sun Young Chae
4Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea;
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Dong Yun Lee
4Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea;
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Sang Ju Lee
4Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea;
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Seung Jun Oh
4Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea;
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Jihun Kim
5Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea;
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Ji Young Kim
6Department of Nuclear Medicine, Hanyang University Medical Center, Hanyang University College of Medicine, Seoul, Republic of Korea;
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Sae Jung Na
7Department of Radiology, Uijeongbu St. Mary’s Hospital, College of Medicine, Catholic University of Korea, Seoul, Republic of Korea;
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Misung Kim
8Department of Pathology, Ulsan University Hospital, Ulsan, Republic of Korea; and
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Sang-Yeob Kim
2Department of Convergence Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea;
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Norman Koglin
9Life Molecular Imaging GmbH, Berlin, Germany
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Andrew W. Stephens
9Life Molecular Imaging GmbH, Berlin, Germany
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Mi-Na Kweon
2Department of Convergence Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea;
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Dae Hyuk Moon
4Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea;
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Journal of Nuclear Medicine: 63 (10)
Journal of Nuclear Medicine
Vol. 63, Issue 10
October 1, 2022
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PET Imaging of System xC− in Immune Cells for Assessment of Disease Activity in Mice and Patients with Inflammatory Bowel Disease
Minjung Seo, Yeji Kim, Byong Duk Ye, Sang Hyoung Park, Seog-Young Kim, Jin Hwa Jung, Sung Wook Hwang, Sun Young Chae, Dong Yun Lee, Sang Ju Lee, Seung Jun Oh, Jihun Kim, Ji Young Kim, Sae Jung Na, Misung Kim, Sang-Yeob Kim, Norman Koglin, Andrew W. Stephens, Mi-Na Kweon, Dae Hyuk Moon
Journal of Nuclear Medicine Oct 2022, 63 (10) 1586-1591; DOI: 10.2967/jnumed.121.263289

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PET Imaging of System xC− in Immune Cells for Assessment of Disease Activity in Mice and Patients with Inflammatory Bowel Disease
Minjung Seo, Yeji Kim, Byong Duk Ye, Sang Hyoung Park, Seog-Young Kim, Jin Hwa Jung, Sung Wook Hwang, Sun Young Chae, Dong Yun Lee, Sang Ju Lee, Seung Jun Oh, Jihun Kim, Ji Young Kim, Sae Jung Na, Misung Kim, Sang-Yeob Kim, Norman Koglin, Andrew W. Stephens, Mi-Na Kweon, Dae Hyuk Moon
Journal of Nuclear Medicine Oct 2022, 63 (10) 1586-1591; DOI: 10.2967/jnumed.121.263289
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Keywords

  • system xC−
  • Immune cells
  • PET
  • inflammatory bowel disease
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