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Research ArticleClinical (Radiobiology/Dosimetry/Safety)

Normal-Tissue Tolerance to Radiopharmaceutical Therapies, the Knowns and the Unknowns

Richard L. Wahl, George Sgouros, Amir Iravani, Heather Jacene, Daniel Pryma, Babak Saboury, Jacek Capala and Stephen A. Graves
Journal of Nuclear Medicine December 2021, 62 (Supplement 3) 23S-35S; DOI: https://doi.org/10.2967/jnumed.121.262751
Richard L. Wahl
1Mallinckrodt Institute of Radiology, Washington University, St. Louis, Missouri
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George Sgouros
2Department of Radiology, Johns Hopkins University, Baltimore, Maryland
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Amir Iravani
1Mallinckrodt Institute of Radiology, Washington University, St. Louis, Missouri
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Heather Jacene
3Dana-Farber Cancer Institute, Boston, Massachusetts
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Daniel Pryma
4Penn Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
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Babak Saboury
5National Institutes of Health, Bethesda, Maryland
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Jacek Capala
5National Institutes of Health, Bethesda, Maryland
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Stephen A. Graves
6University of Iowa, Iowa City, Iowa
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Article Information

vol. 62 no. Supplement 3 23S-35S
DOI 
https://doi.org/10.2967/jnumed.121.262751
PubMed 
34857619

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication August 24, 2021
  • Revision received October 15, 2021
  • Published online December 2, 2021.

Copyright & Usage 
© 2021 by the Society of Nuclear Medicine and Molecular Imaging.

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Journal of Nuclear Medicine: 62 (Supplement 3)
Journal of Nuclear Medicine
Vol. 62, Issue Supplement 3
December 1, 2021
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Normal-Tissue Tolerance to Radiopharmaceutical Therapies, the Knowns and the Unknowns
Richard L. Wahl, George Sgouros, Amir Iravani, Heather Jacene, Daniel Pryma, Babak Saboury, Jacek Capala, Stephen A. Graves
Journal of Nuclear Medicine Dec 2021, 62 (Supplement 3) 23S-35S; DOI: 10.2967/jnumed.121.262751

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Normal-Tissue Tolerance to Radiopharmaceutical Therapies, the Knowns and the Unknowns
Richard L. Wahl, George Sgouros, Amir Iravani, Heather Jacene, Daniel Pryma, Babak Saboury, Jacek Capala, Stephen A. Graves
Journal of Nuclear Medicine Dec 2021, 62 (Supplement 3) 23S-35S; DOI: 10.2967/jnumed.121.262751
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  • Article
    • MECHANISM OF IRRADIATION FROM RPT
    • DOSE RATE, Biologically Effective Dose (BED), AND MICRODISTRIBUTION OF DOSE
    • NORMAL-TISSUE DOSE LIMITS
    • SECONDARY MALIGNANCIES AND SIDE EFFECTS
    • CONFOUNDING CLINICAL FACTORS
    • SUMMARY AND FUTURE DIRECTIONS
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  • Dosimetry for Radiopharmaceutical Therapy: Current Practices and Commercial Resources
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