A Phase 1 and Biodistribution Study of ABT-806i, an 111In-Radiolabeled Conjugate of the Tumor-Specific Anti-EGFR Antibody ABT-806

Hui K. Gan; Matthew Burge; Benjamin Solomon; Sze Ting Lee; Kyle D. Holen; Yumin Zhang; Marika Ciprotti; F.T. Lee; Wijith Munasinghe; JuDee Fischer; Peter Ansell; Gerard Fox; Hao Xiong; Edward B. Reilly; Rod Humerickhouse; Andrew M. Scott

doi:10.2967/jnumed.120.253146

Research ArticleClinical Investigation

A Phase 1 and Biodistribution Study of ABT-806i, an ¹¹¹In-Radiolabeled Conjugate of the Tumor-Specific Anti-EGFR Antibody ABT-806

Hui K. Gan, Matthew Burge, Benjamin Solomon, Sze Ting Lee, Kyle D. Holen, Yumin Zhang, Marika Ciprotti, F.T. Lee, Wijith Munasinghe, JuDee Fischer, Peter Ansell, Gerard Fox, Hao Xiong, Edward B. Reilly, Rod Humerickhouse and Andrew M. Scott

Journal of Nuclear Medicine June 2021, 62 (6) 787-794; DOI: https://doi.org/10.2967/jnumed.120.253146

Hui K. Gan

1Olivia Newton-John Cancer Research Institute, Austin Health, Melbourne, Australia

2School of Cancer Medicine, La Trobe University, Melbourne, Australia

3Department of Medicine, University of Melbourne, Melbourne, Australia

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Matthew Burge

4Royal Brisbane and Women's Hospital, Brisbane, Australia

5University of Queensland, Brisbane, Australia

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Benjamin Solomon

3Department of Medicine, University of Melbourne, Melbourne, Australia

6Peter MacCallum Cancer Centre, Melbourne, Australia

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Sze Ting Lee

1Olivia Newton-John Cancer Research Institute, Austin Health, Melbourne, Australia

2School of Cancer Medicine, La Trobe University, Melbourne, Australia

7Department of Molecular Imaging and Therapy, Austin Health, Melbourne, Australia

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Kyle D. Holen

8AbbVie, North Chicago, Illinois; and

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Yumin Zhang

9Sinotau Pharmaceutical Group, Beijing, China

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Marika Ciprotti

1Olivia Newton-John Cancer Research Institute, Austin Health, Melbourne, Australia

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

F.T. Lee

1Olivia Newton-John Cancer Research Institute, Austin Health, Melbourne, Australia

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Wijith Munasinghe

8AbbVie, North Chicago, Illinois; and

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

JuDee Fischer

8AbbVie, North Chicago, Illinois; and

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Peter Ansell

8AbbVie, North Chicago, Illinois; and

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Gerard Fox

8AbbVie, North Chicago, Illinois; and

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Hao Xiong

8AbbVie, North Chicago, Illinois; and

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Edward B. Reilly

8AbbVie, North Chicago, Illinois; and

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Rod Humerickhouse

8AbbVie, North Chicago, Illinois; and

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Andrew M. Scott

1Olivia Newton-John Cancer Research Institute, Austin Health, Melbourne, Australia

2School of Cancer Medicine, La Trobe University, Melbourne, Australia

3Department of Medicine, University of Melbourne, Melbourne, Australia

7Department of Molecular Imaging and Therapy, Austin Health, Melbourne, Australia

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Article
Figures & Data
Supplemental
Info & Metrics
PDF

Data supplements

Supplemental Data

Files in this Data Supplement:

Supplemental Data

PreviousNext

In this issue

Journal of Nuclear Medicine

Vol. 62, Issue 6

June 1, 2021

Table of Contents
Table of Contents (PDF)
About the Cover
Index by author

Download PDF

Article Alerts

User Name *

Password *

Email *

Email Article

Thank you for your interest in spreading the word on Journal of Nuclear Medicine.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following A Phase 1 and Biodistribution Study of ABT-806i, an 111In-Radiolabeled Conjugate of the Tumor-Specific Anti-EGFR Antibody ABT-806

Message Subject (Your Name) has sent you a message from Journal of Nuclear Medicine

Message Body (Your Name) thought you would like to see the Journal of Nuclear Medicine web site.

Your Personal Message

Citation Tools

A Phase 1 and Biodistribution Study of ABT-806i, an ¹¹¹In-Radiolabeled Conjugate of the Tumor-Specific Anti-EGFR Antibody ABT-806

Journal of Nuclear Medicine Jun 2021, 62 (6) 787-794; DOI: 10.2967/jnumed.120.253146

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

A Phase 1 and Biodistribution Study of ABT-806i, an ¹¹¹In-Radiolabeled Conjugate of the Tumor-Specific Anti-EGFR Antibody ABT-806

Journal of Nuclear Medicine Jun 2021, 62 (6) 787-794; DOI: 10.2967/jnumed.120.253146

Share This Article:

Tweet Widget
Facebook Like
Google Plus One

Bookmark this article

User Name *

Password *

Remember my user name & password.

Jump to section

Article
Figures & Data
Supplemental
Info & Metrics
PDF

This Month in JNM

PubMed
Google Scholar

Cited By...

Radiolabeling and Preclinical Evaluation of Therapeutic Efficacy of 225Ac-ch806 in Glioblastoma and Colorectal Cancer Xenograft Models

Google Scholar

Keywords

EGFR
EGFRvIII
solid tumors
SPECT imaging
biodistribution

Main menu

User menu

Search

A Phase 1 and Biodistribution Study of ABT-806i, an ¹¹¹In-Radiolabeled Conjugate of the Tumor-Specific Anti-EGFR Antibody ABT-806

Data supplements

Supplemental Data

In this issue

Citation Manager Formats

Related Articles

Cited By...

More in this TOC Section

Similar Articles

Keywords