Article Figures & Data
Figures
- FIGURE 1.
VOIs used for parameter estimation.
- FIGURE 2.
Image-derived input function for first 90 s after injection. AU = arbitrary units.
- FIGURE 3.
Maximum-intensity projection of reconstructed parametric images
and k1 acquired using proposed approach. - FIGURE 4.
Coronal plane of reconstructed k1, k1,
, and
parametric images using proposed method from volunteer 1, together with SUV image. - FIGURE 5.
Estimated k1, k2, and vb for 9 VOIs using 1T model with 90 s of data (y-axis) and 2Ti model with 1 h of data (x-axis).
- FIGURE 6.
Time–activity curve measured from dynamic frames (blue dots) and fitted curves using proposed method, and fitting based on time–activity curve from VOI in 4 different organs: myocardium, brain, liver, and lung. For better illustration of delay time, corresponding blood fraction in time–activity curve was also plotted. AU = arbitrary units.
Tables
Parameter Gray matter White matter Myocardium Liver Kidney cortex Spleen Lung Arm Thigh k1 (min−1) VOI analysis 0.08 0.05 0.56 0.39 0.75 0.92 0.02 0.02 0.06 k1 (min−1) parametric image 0.09 ± 0.02 0.06 ± 0.01 0.45 ± 0.10 0.33 ± 0.04 0.54 ± 0.08 0.73 ± 0.13 0.02 ± 0.02 0.02 ± 0.01 0.06 ± 0.03 Cb VOI analysis 0.020 0.01 0.02 0.006 0.08 0.006 0.12 0.0004 0.0 Cb parametric image 0.020 ± 0.01 0.007 ± 0.005 0.05 ± 0.04 0.003 ± 0.005 0.11 ± 0.03 0.03 ± 0.02 0.12 ± 0.03 0.0009 ± 0.001 0.004 ± 0.01 Delay time (s) 3.9 3.7 −1.2 13.1 4.7 3.1 −3.8 10.8 8.6
Supplemental Data
Files in this Data Supplement:
Jump to section
Related Articles
Cited By...
- Quantitative Total-Body Imaging of Blood Flow with High-Temporal-Resolution Early Dynamic 18F-FDG PET Kinetic Modeling
- Quantitative Total-Body Imaging of Blood Flow with High Temporal Resolution Early Dynamic 18F-Fluorodeoxyglucose PET Kinetic Modeling
- Quantitative PET imaging and modeling of molecular blood-brain barrier permeability
- Mapping 18F-FDG Kinetics Together with Patient-Specific Bootstrap Assessment of Uncertainties: An Illustration with Data from a PET/CT Scanner with a Long Axial Field of View
- High-Temporal-Resolution Kinetic Modeling of Lung Tumors with Dual-Blood Input Function Using Total-Body Dynamic PET
- Clinical Implementation of Total-Body PET in China
- Total-Body PET/CT Applications in Cardiovascular Diseases: A Perspective Document of the SNMMI Cardiovascular Council
- High-Temporal-Resolution Lung Kinetic Modeling Using Total-Body Dynamic PET with Time-Delay and Dispersion Corrections
- Blanching Defects at Pressure Points: Observations from Dynamic Total-Body PET/CT Studies
- Total-Body PET Multiparametric Imaging of Cancer Using a Voxelwise Strategy of Compartmental Modeling
- Efficient Delay Correction for Total-Body PET Kinetic Modeling Using Pulse Timing Methods
- Whole-Body Parametric Imaging of 18F-FDG PET Using uEXPLORER with Reduced Scanning Time