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Research ArticleTheranostics

Head-to-Head Comparison of 68Ga-PSMA-11 with 18F-PSMA-1007 PET/CT in Staging Prostate Cancer Using Histopathology and Immunohistochemical Analysis as a Reference Standard

Jonathan Kuten, Ibrahim Fahoum, Ziv Savin, Ofer Shamni, Gilad Gitstein, Dov Hershkovitz, Nicola J. Mabjeesh, Ofer Yossepowitch, Eyal Mishani and Einat Even-Sapir
Journal of Nuclear Medicine April 2020, 61 (4) 527-532; DOI: https://doi.org/10.2967/jnumed.119.234187
Jonathan Kuten
1Department of Nuclear Medicine, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
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Ibrahim Fahoum
2Department of Pathology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
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Ziv Savin
3Department of Urology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
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Ofer Shamni
4Hadassah Cyclotron Unit, Hadassah Medical Center, Jerusalem, Israel; and
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Gilad Gitstein
2Department of Pathology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
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Dov Hershkovitz
2Department of Pathology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
5Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
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Nicola J. Mabjeesh
3Department of Urology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
5Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
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Ofer Yossepowitch
3Department of Urology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
5Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
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Eyal Mishani
4Hadassah Cyclotron Unit, Hadassah Medical Center, Jerusalem, Israel; and
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Einat Even-Sapir
1Department of Nuclear Medicine, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
5Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
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Journal of Nuclear Medicine: 61 (4)
Journal of Nuclear Medicine
Vol. 61, Issue 4
April 1, 2020
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Head-to-Head Comparison of 68Ga-PSMA-11 with 18F-PSMA-1007 PET/CT in Staging Prostate Cancer Using Histopathology and Immunohistochemical Analysis as a Reference Standard
Jonathan Kuten, Ibrahim Fahoum, Ziv Savin, Ofer Shamni, Gilad Gitstein, Dov Hershkovitz, Nicola J. Mabjeesh, Ofer Yossepowitch, Eyal Mishani, Einat Even-Sapir
Journal of Nuclear Medicine Apr 2020, 61 (4) 527-532; DOI: 10.2967/jnumed.119.234187

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Head-to-Head Comparison of 68Ga-PSMA-11 with 18F-PSMA-1007 PET/CT in Staging Prostate Cancer Using Histopathology and Immunohistochemical Analysis as a Reference Standard
Jonathan Kuten, Ibrahim Fahoum, Ziv Savin, Ofer Shamni, Gilad Gitstein, Dov Hershkovitz, Nicola J. Mabjeesh, Ofer Yossepowitch, Eyal Mishani, Einat Even-Sapir
Journal of Nuclear Medicine Apr 2020, 61 (4) 527-532; DOI: 10.2967/jnumed.119.234187
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Cited By...

  • Limitations of Retrospective Study Design and Potential Bias in the PRECISE-MDT Study
  • Diagnostic Performance of [18F]AlF-Thretide PET/CT in Patients with Newly Diagnosed Prostate Cancer Using Histopathology as Reference Standard
  • Protocol for SNOTOB study: radical prostatectomy without prostate biopsy following 18F-PSMA-1007 PET/CT based on a diagnostic model: a single-centre, single-arm, open-label study
  • Identification of alternative protein targets of glutamate-ureido-lysine associated with PSMA tracer uptake in prostate cancer cells
  • Appropriate Use Criteria for Prostate-Specific Membrane Antigen PET Imaging
  • Prostate-specific membrane antigen positron emission tomography compared to multiparametric MRI for prostate cancer diagnosis: a protocol for a systematic review and meta-analysis
  • Tumor Detection of 18F-PSMA-1007 in the Prostate Gland in Patients with Prostate Cancer Using Prostatectomy Specimens as Reference Method
  • Combination of Forced Diuresis with Additional Late Imaging in 68Ga-PSMA-11 PET/CT: Effects on Lesion Visibility and Radiotracer Uptake
  • Matched-Pair Comparison of 68Ga-PSMA-11 and 18F-rhPSMA-7 PET/CT in Patients with Primary and Biochemical Recurrence of Prostate Cancer: Frequency of Non-Tumor-Related Uptake and Tumor Positivity
  • Diagnostic Performance of 18F-DCFPyL-PET/CT in Men with Biochemically Recurrent Prostate Cancer: Results from the CONDOR Phase III, Multicenter Study
  • Intraprostatic Tumor Segmentation on PSMA PET Images in Patients with Primary Prostate Cancer with a Convolutional Neural Network
  • Diagnostic Accuracy of 18F-PSMA-1007 PET/CT Imaging for Lymph Node Staging of Prostate Carcinoma in Primary and Biochemical Recurrence
  • Factors Predicting Metastatic Disease in 68Ga-PSMA-11 PET-Positive Osseous Lesions in Prostate Cancer
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More in this TOC Section

Theranostics

  • Determination of the Intralesional Distribution of Theranostic 124I-Omburtamab Convection-Enhanced Delivery in Treatment of Diffuse Intrinsic Pontine Glioma
  • Evidence-Based Clinical Protocols to Monitor Efficacy of [177Lu]Lu-PSMA Radiopharmaceutical Therapy in Metastatic Castration-Resistant Prostate Cancer Using Real-World Data
  • 177Lu-Labeled Anticlaudin 6 Monoclonal Antibody for Targeted Therapy in Esophageal Cancer
Show more Theranostics

Clinical

  • Determination of the Intralesional Distribution of Theranostic 124I-Omburtamab Convection-Enhanced Delivery in Treatment of Diffuse Intrinsic Pontine Glioma
  • Evidence-Based Clinical Protocols to Monitor Efficacy of [177Lu]Lu-PSMA Radiopharmaceutical Therapy in Metastatic Castration-Resistant Prostate Cancer Using Real-World Data
  • 177Lu-Labeled Anticlaudin 6 Monoclonal Antibody for Targeted Therapy in Esophageal Cancer
Show more Clinical

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Keywords

  • 18F-PSMA-1007
  • 68Ga-PSMA-11
  • prostate cancer
  • comparison
  • staging
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