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Research ArticleCardiovascular

Folate Receptor β–Targeted PET Imaging of Macrophages in Autoimmune Myocarditis

Arghavan Jahandideh, Sauli Uotila, Mia Ståhle, Jenni Virta, Xiang-Guo Li, Ville Kytö, Päivi Marjamäki, Heidi Liljenbäck, Pekka Taimen, Vesa Oikonen, Jukka Lehtonen, Mikko I. Mäyränpää, Qingshou Chen, Philip S. Low, Juhani Knuuti, Anne Roivainen and Antti Saraste
Journal of Nuclear Medicine November 2020, 61 (11) 1643-1649; DOI: https://doi.org/10.2967/jnumed.119.241356
Arghavan Jahandideh
1Turku PET Centre, University of Turku, Turku, Finland
2Turku PET Centre, Turku University Hospital, Turku, Finland
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Sauli Uotila
1Turku PET Centre, University of Turku, Turku, Finland
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Mia Ståhle
1Turku PET Centre, University of Turku, Turku, Finland
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Jenni Virta
1Turku PET Centre, University of Turku, Turku, Finland
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Xiang-Guo Li
1Turku PET Centre, University of Turku, Turku, Finland
3Turku PET Centre, Åbo Akademi University, Turku, Finland
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Ville Kytö
4Heart Center, Turku University Hospital and University of Turku, Turku, Finland
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Päivi Marjamäki
1Turku PET Centre, University of Turku, Turku, Finland
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Heidi Liljenbäck
1Turku PET Centre, University of Turku, Turku, Finland
5Turku Center for Disease Modeling, University of Turku, Turku, Finland
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Pekka Taimen
6Institute of Biomedicine, University of Turku and Department of Pathology, Turku University Hospital, Turku, Finland
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Vesa Oikonen
1Turku PET Centre, University of Turku, Turku, Finland
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Jukka Lehtonen
7Heart and Lung Center, Helsinki University and Helsinki University Hospital, Helsinki, Finland
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Mikko I. Mäyränpää
8Pathology, Helsinki University and Helsinki University Hospital, Helsinki, Finland; and
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Qingshou Chen
9Department of Chemistry, Purdue University, West Lafayette, Indiana
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Philip S. Low
9Department of Chemistry, Purdue University, West Lafayette, Indiana
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Juhani Knuuti
1Turku PET Centre, University of Turku, Turku, Finland
2Turku PET Centre, Turku University Hospital, Turku, Finland
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Anne Roivainen
1Turku PET Centre, University of Turku, Turku, Finland
2Turku PET Centre, Turku University Hospital, Turku, Finland
5Turku Center for Disease Modeling, University of Turku, Turku, Finland
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Antti Saraste
1Turku PET Centre, University of Turku, Turku, Finland
2Turku PET Centre, Turku University Hospital, Turku, Finland
4Heart Center, Turku University Hospital and University of Turku, Turku, Finland
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Article Information

vol. 61 no. 11 1643-1649
DOI 
https://doi.org/10.2967/jnumed.119.241356
PubMed 
32284397

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication December 23, 2019
  • Accepted for publication February 26, 2020
  • Published online November 2, 2020.

Article Versions

  • previous version (April 13, 2020 - 14:09).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2020 by the Society of Nuclear Medicine and Molecular Imaging.

Author Information

  1. Arghavan Jahandideh1,2,
  2. Sauli Uotila1,
  3. Mia Ståhle1,
  4. Jenni Virta1,
  5. Xiang-Guo Li1,3,
  6. Ville Kytö4,
  7. Päivi Marjamäki1,
  8. Heidi Liljenbäck1,5,
  9. Pekka Taimen6,
  10. Vesa Oikonen1,
  11. Jukka Lehtonen7,
  12. Mikko I. Mäyränpää8,
  13. Qingshou Chen9,
  14. Philip S. Low9,
  15. Juhani Knuuti1,2,
  16. Anne Roivainen1,2,5 and
  17. Antti Saraste1,2,4
  1. 1Turku PET Centre, University of Turku, Turku, Finland
  2. 2Turku PET Centre, Turku University Hospital, Turku, Finland
  3. 3Turku PET Centre, Åbo Akademi University, Turku, Finland
  4. 4Heart Center, Turku University Hospital and University of Turku, Turku, Finland
  5. 5Turku Center for Disease Modeling, University of Turku, Turku, Finland
  6. 6Institute of Biomedicine, University of Turku and Department of Pathology, Turku University Hospital, Turku, Finland
  7. 7Heart and Lung Center, Helsinki University and Helsinki University Hospital, Helsinki, Finland
  8. 8Pathology, Helsinki University and Helsinki University Hospital, Helsinki, Finland; and
  9. 9Department of Chemistry, Purdue University, West Lafayette, Indiana
  1. For correspondence or reprints contact: Antti Saraste, Heart Center, Turku University Hospital, Hämeentie 11, FI-20520 Turku, Finland. E-mail: antti.saraste{at}utu.fi
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Journal of Nuclear Medicine: 61 (11)
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November 1, 2020
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Folate Receptor β–Targeted PET Imaging of Macrophages in Autoimmune Myocarditis
Arghavan Jahandideh, Sauli Uotila, Mia Ståhle, Jenni Virta, Xiang-Guo Li, Ville Kytö, Päivi Marjamäki, Heidi Liljenbäck, Pekka Taimen, Vesa Oikonen, Jukka Lehtonen, Mikko I. Mäyränpää, Qingshou Chen, Philip S. Low, Juhani Knuuti, Anne Roivainen, Antti Saraste
Journal of Nuclear Medicine Nov 2020, 61 (11) 1643-1649; DOI: 10.2967/jnumed.119.241356

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Folate Receptor β–Targeted PET Imaging of Macrophages in Autoimmune Myocarditis
Arghavan Jahandideh, Sauli Uotila, Mia Ståhle, Jenni Virta, Xiang-Guo Li, Ville Kytö, Päivi Marjamäki, Heidi Liljenbäck, Pekka Taimen, Vesa Oikonen, Jukka Lehtonen, Mikko I. Mäyränpää, Qingshou Chen, Philip S. Low, Juhani Knuuti, Anne Roivainen, Antti Saraste
Journal of Nuclear Medicine Nov 2020, 61 (11) 1643-1649; DOI: 10.2967/jnumed.119.241356
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Keywords

  • folate receptor
  • PET
  • myocarditis
  • experimental autoimmune myocarditis
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