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Research ArticleNeurology

Preclinical Evaluation and Nonhuman Primate Receptor Occupancy Study of 18F-JNJ-64413739, a PET Radioligand for P2X7 Receptors

Hartmuth C. Kolb, Olivier Barret, Anindya Bhattacharya, Gang Chen, Cristian Constantinescu, Chaofeng Huang, Michael Letavic, Gilles Tamagnan, Chunfang A. Xia, Wei Zhang and Anna Katrin Szardenings
Journal of Nuclear Medicine August 2019, 60 (8) 1154-1159; DOI: https://doi.org/10.2967/jnumed.118.212696
Hartmuth C. Kolb
1Janssen Research and Development LLC, San Diego, California; and
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Olivier Barret
2MNI, a Division of Invicro, New Haven, Connecticut
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Anindya Bhattacharya
1Janssen Research and Development LLC, San Diego, California; and
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Gang Chen
1Janssen Research and Development LLC, San Diego, California; and
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Cristian Constantinescu
2MNI, a Division of Invicro, New Haven, Connecticut
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Chaofeng Huang
1Janssen Research and Development LLC, San Diego, California; and
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Michael Letavic
1Janssen Research and Development LLC, San Diego, California; and
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Gilles Tamagnan
2MNI, a Division of Invicro, New Haven, Connecticut
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Chunfang A. Xia
1Janssen Research and Development LLC, San Diego, California; and
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Wei Zhang
1Janssen Research and Development LLC, San Diego, California; and
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Anna Katrin Szardenings
1Janssen Research and Development LLC, San Diego, California; and
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Article Information

vol. 60 no. 8 1154-1159
DOI 
https://doi.org/10.2967/jnumed.118.212696
PubMed 
30733317

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication April 30, 2018
  • Accepted for publication January 1, 2019
  • Published online August 1, 2019.

Article Versions

  • previous version (February 7, 2019 - 09:19).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2019 by the Society of Nuclear Medicine and Molecular Imaging.

Author Information

  1. Hartmuth C. Kolb1,
  2. Olivier Barret2,
  3. Anindya Bhattacharya1,
  4. Gang Chen1,
  5. Cristian Constantinescu2,
  6. Chaofeng Huang1,
  7. Michael Letavic1,
  8. Gilles Tamagnan2,
  9. Chunfang A. Xia1,
  10. Wei Zhang1 and
  11. Anna Katrin Szardenings1
  1. 1Janssen Research and Development LLC, San Diego, California; and
  2. 2MNI, a Division of Invicro, New Haven, Connecticut
  1. For correspondence or reprints contact: Anna Katrin Szardenings, Janssen Research and Development LLC, 3210 Merryfield Row, San Diego, CA 92121. E-mail: aszarden{at}its.jnj.com
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Journal of Nuclear Medicine: 60 (8)
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Preclinical Evaluation and Nonhuman Primate Receptor Occupancy Study of 18F-JNJ-64413739, a PET Radioligand for P2X7 Receptors
Hartmuth C. Kolb, Olivier Barret, Anindya Bhattacharya, Gang Chen, Cristian Constantinescu, Chaofeng Huang, Michael Letavic, Gilles Tamagnan, Chunfang A. Xia, Wei Zhang, Anna Katrin Szardenings
Journal of Nuclear Medicine Aug 2019, 60 (8) 1154-1159; DOI: 10.2967/jnumed.118.212696

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Preclinical Evaluation and Nonhuman Primate Receptor Occupancy Study of 18F-JNJ-64413739, a PET Radioligand for P2X7 Receptors
Hartmuth C. Kolb, Olivier Barret, Anindya Bhattacharya, Gang Chen, Cristian Constantinescu, Chaofeng Huang, Michael Letavic, Gilles Tamagnan, Chunfang A. Xia, Wei Zhang, Anna Katrin Szardenings
Journal of Nuclear Medicine Aug 2019, 60 (8) 1154-1159; DOI: 10.2967/jnumed.118.212696
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