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Research ArticleTheranostics

Discovery of 18F-JK-PSMA-7, a PET Probe for the Detection of Small PSMA-Positive Lesions

Boris D. Zlatopolskiy, Heike Endepols, Philipp Krapf, Mehrab Guliyev, Elizaveta A. Urusova, Raphael Richarz, Melanie Hohberg, Markus Dietlein, Alexander Drzezga and Bernd Neumaier
Journal of Nuclear Medicine June 2019, 60 (6) 817-823; DOI: https://doi.org/10.2967/jnumed.118.218495
Boris D. Zlatopolskiy
1Institute of Radiochemistry and Experimental Molecular Imaging, University Hospital of Cologne, Cologne, Germany
2Institute of Neuroscience and Medicine, INM-5: Nuclear Chemistry, Forschungszentrum Jülich GmbH, Jülich, Germany
3Max Planck Institute for Metabolism Research, Cologne, Germany; and
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Heike Endepols
1Institute of Radiochemistry and Experimental Molecular Imaging, University Hospital of Cologne, Cologne, Germany
2Institute of Neuroscience and Medicine, INM-5: Nuclear Chemistry, Forschungszentrum Jülich GmbH, Jülich, Germany
4Department of Nuclear Medicine, University Hospital of Cologne, Cologne, Germany
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Philipp Krapf
1Institute of Radiochemistry and Experimental Molecular Imaging, University Hospital of Cologne, Cologne, Germany
2Institute of Neuroscience and Medicine, INM-5: Nuclear Chemistry, Forschungszentrum Jülich GmbH, Jülich, Germany
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Mehrab Guliyev
1Institute of Radiochemistry and Experimental Molecular Imaging, University Hospital of Cologne, Cologne, Germany
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Elizaveta A. Urusova
1Institute of Radiochemistry and Experimental Molecular Imaging, University Hospital of Cologne, Cologne, Germany
2Institute of Neuroscience and Medicine, INM-5: Nuclear Chemistry, Forschungszentrum Jülich GmbH, Jülich, Germany
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Raphael Richarz
1Institute of Radiochemistry and Experimental Molecular Imaging, University Hospital of Cologne, Cologne, Germany
2Institute of Neuroscience and Medicine, INM-5: Nuclear Chemistry, Forschungszentrum Jülich GmbH, Jülich, Germany
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Melanie Hohberg
4Department of Nuclear Medicine, University Hospital of Cologne, Cologne, Germany
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Markus Dietlein
4Department of Nuclear Medicine, University Hospital of Cologne, Cologne, Germany
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Alexander Drzezga
4Department of Nuclear Medicine, University Hospital of Cologne, Cologne, Germany
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Bernd Neumaier
1Institute of Radiochemistry and Experimental Molecular Imaging, University Hospital of Cologne, Cologne, Germany
2Institute of Neuroscience and Medicine, INM-5: Nuclear Chemistry, Forschungszentrum Jülich GmbH, Jülich, Germany
3Max Planck Institute for Metabolism Research, Cologne, Germany; and
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Journal of Nuclear Medicine: 60 (6)
Journal of Nuclear Medicine
Vol. 60, Issue 6
June 1, 2019
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Discovery of 18F-JK-PSMA-7, a PET Probe for the Detection of Small PSMA-Positive Lesions
Boris D. Zlatopolskiy, Heike Endepols, Philipp Krapf, Mehrab Guliyev, Elizaveta A. Urusova, Raphael Richarz, Melanie Hohberg, Markus Dietlein, Alexander Drzezga, Bernd Neumaier
Journal of Nuclear Medicine Jun 2019, 60 (6) 817-823; DOI: 10.2967/jnumed.118.218495

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Discovery of 18F-JK-PSMA-7, a PET Probe for the Detection of Small PSMA-Positive Lesions
Boris D. Zlatopolskiy, Heike Endepols, Philipp Krapf, Mehrab Guliyev, Elizaveta A. Urusova, Raphael Richarz, Melanie Hohberg, Markus Dietlein, Alexander Drzezga, Bernd Neumaier
Journal of Nuclear Medicine Jun 2019, 60 (6) 817-823; DOI: 10.2967/jnumed.118.218495
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Keywords

  • prostate carcinoma
  • PSMA
  • radiofluorination
  • Positron emission tomography
  • imaging
  • preclinical model
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