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Research ArticleNeurology

Alteration of Monoamine Receptor Activity and Glucose Metabolism in Pediatric Patients with Anticonvulsant-Induced Cognitive Impairment

Yuankai Zhu, Jianhua Feng, Jianfeng Ji, Haifeng Hou, Lin Chen, Shuang Wu, Qing Liu, Qiong Yao, Peizhen Du, Kai Zhang, Qing Chen, Zexin Chen, Hong Zhang and Mei Tian
Journal of Nuclear Medicine September 2017, 58 (9) 1490-1497; DOI: https://doi.org/10.2967/jnumed.116.189290
Yuankai Zhu
1Department of Nuclear Medicine, The Second Hospital of Zhejiang University School of Medicine, Hangzhou, China
2Zhejiang University Medical PET Centre, Zhejiang University, Hangzhou, China
3Institute of Nuclear Medicine and Molecular Imaging, Zhejiang University, Hangzhou, China
4Key Laboratory of Medical Molecular Imaging of Zhejiang Province, Hangzhou, China
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Jianhua Feng
5Department of Paediatrics, The Second Hospital of Zhejiang University School of Medicine, Hangzhou, China; and
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Jianfeng Ji
1Department of Nuclear Medicine, The Second Hospital of Zhejiang University School of Medicine, Hangzhou, China
2Zhejiang University Medical PET Centre, Zhejiang University, Hangzhou, China
3Institute of Nuclear Medicine and Molecular Imaging, Zhejiang University, Hangzhou, China
4Key Laboratory of Medical Molecular Imaging of Zhejiang Province, Hangzhou, China
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Haifeng Hou
1Department of Nuclear Medicine, The Second Hospital of Zhejiang University School of Medicine, Hangzhou, China
2Zhejiang University Medical PET Centre, Zhejiang University, Hangzhou, China
3Institute of Nuclear Medicine and Molecular Imaging, Zhejiang University, Hangzhou, China
4Key Laboratory of Medical Molecular Imaging of Zhejiang Province, Hangzhou, China
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Lin Chen
1Department of Nuclear Medicine, The Second Hospital of Zhejiang University School of Medicine, Hangzhou, China
2Zhejiang University Medical PET Centre, Zhejiang University, Hangzhou, China
3Institute of Nuclear Medicine and Molecular Imaging, Zhejiang University, Hangzhou, China
4Key Laboratory of Medical Molecular Imaging of Zhejiang Province, Hangzhou, China
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Shuang Wu
1Department of Nuclear Medicine, The Second Hospital of Zhejiang University School of Medicine, Hangzhou, China
2Zhejiang University Medical PET Centre, Zhejiang University, Hangzhou, China
3Institute of Nuclear Medicine and Molecular Imaging, Zhejiang University, Hangzhou, China
4Key Laboratory of Medical Molecular Imaging of Zhejiang Province, Hangzhou, China
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Qing Liu
1Department of Nuclear Medicine, The Second Hospital of Zhejiang University School of Medicine, Hangzhou, China
2Zhejiang University Medical PET Centre, Zhejiang University, Hangzhou, China
3Institute of Nuclear Medicine and Molecular Imaging, Zhejiang University, Hangzhou, China
4Key Laboratory of Medical Molecular Imaging of Zhejiang Province, Hangzhou, China
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Qiong Yao
1Department of Nuclear Medicine, The Second Hospital of Zhejiang University School of Medicine, Hangzhou, China
2Zhejiang University Medical PET Centre, Zhejiang University, Hangzhou, China
3Institute of Nuclear Medicine and Molecular Imaging, Zhejiang University, Hangzhou, China
4Key Laboratory of Medical Molecular Imaging of Zhejiang Province, Hangzhou, China
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Peizhen Du
1Department of Nuclear Medicine, The Second Hospital of Zhejiang University School of Medicine, Hangzhou, China
2Zhejiang University Medical PET Centre, Zhejiang University, Hangzhou, China
3Institute of Nuclear Medicine and Molecular Imaging, Zhejiang University, Hangzhou, China
4Key Laboratory of Medical Molecular Imaging of Zhejiang Province, Hangzhou, China
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Kai Zhang
1Department of Nuclear Medicine, The Second Hospital of Zhejiang University School of Medicine, Hangzhou, China
2Zhejiang University Medical PET Centre, Zhejiang University, Hangzhou, China
3Institute of Nuclear Medicine and Molecular Imaging, Zhejiang University, Hangzhou, China
4Key Laboratory of Medical Molecular Imaging of Zhejiang Province, Hangzhou, China
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Qing Chen
1Department of Nuclear Medicine, The Second Hospital of Zhejiang University School of Medicine, Hangzhou, China
2Zhejiang University Medical PET Centre, Zhejiang University, Hangzhou, China
3Institute of Nuclear Medicine and Molecular Imaging, Zhejiang University, Hangzhou, China
4Key Laboratory of Medical Molecular Imaging of Zhejiang Province, Hangzhou, China
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Zexin Chen
6Department of Clinical Epidemiology & Biostatistics, The Second Hospital of Zhejiang University School of Medicine, Hangzhou, China
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Hong Zhang
1Department of Nuclear Medicine, The Second Hospital of Zhejiang University School of Medicine, Hangzhou, China
2Zhejiang University Medical PET Centre, Zhejiang University, Hangzhou, China
3Institute of Nuclear Medicine and Molecular Imaging, Zhejiang University, Hangzhou, China
4Key Laboratory of Medical Molecular Imaging of Zhejiang Province, Hangzhou, China
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Mei Tian
1Department of Nuclear Medicine, The Second Hospital of Zhejiang University School of Medicine, Hangzhou, China
2Zhejiang University Medical PET Centre, Zhejiang University, Hangzhou, China
3Institute of Nuclear Medicine and Molecular Imaging, Zhejiang University, Hangzhou, China
4Key Laboratory of Medical Molecular Imaging of Zhejiang Province, Hangzhou, China
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Article Information

vol. 58 no. 9 1490-1497
DOI 
https://doi.org/10.2967/jnumed.116.189290
PubMed 
28302757

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication December 29, 2016
  • Accepted for publication February 27, 2017
  • Published online September 1, 2017.

Article Versions

  • previous version (March 16, 2017 - 04:46).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2017 by the Society of Nuclear Medicine and Molecular Imaging.

Author Information

  1. Yuankai Zhu*,1–4,
  2. Jianhua Feng*,5,
  3. Jianfeng Ji*,1–4,
  4. Haifeng Hou1–4,
  5. Lin Chen1–4,
  6. Shuang Wu1–4,
  7. Qing Liu1–4,
  8. Qiong Yao1–4,
  9. Peizhen Du1–4,
  10. Kai Zhang1–4,
  11. Qing Chen1–4,
  12. Zexin Chen6,
  13. Hong Zhang1–4 and
  14. Mei Tian1–4
  1. 1Department of Nuclear Medicine, The Second Hospital of Zhejiang University School of Medicine, Hangzhou, China
  2. 2Zhejiang University Medical PET Centre, Zhejiang University, Hangzhou, China
  3. 3Institute of Nuclear Medicine and Molecular Imaging, Zhejiang University, Hangzhou, China
  4. 4Key Laboratory of Medical Molecular Imaging of Zhejiang Province, Hangzhou, China
  5. 5Department of Paediatrics, The Second Hospital of Zhejiang University School of Medicine, Hangzhou, China; and
  6. 6Department of Clinical Epidemiology & Biostatistics, The Second Hospital of Zhejiang University School of Medicine, Hangzhou, China
  1. For correspondence or reprints contact: Mei Tian, Department of Nuclear Medicine, The Second Hospital of Zhejiang University, 88 Jiefang Rd., Hangzhou, Zhejiang 310009, China. E-mail: meitian{at}zju.edu.cn
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Journal of Nuclear Medicine: 58 (9)
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Alteration of Monoamine Receptor Activity and Glucose Metabolism in Pediatric Patients with Anticonvulsant-Induced Cognitive Impairment
Yuankai Zhu, Jianhua Feng, Jianfeng Ji, Haifeng Hou, Lin Chen, Shuang Wu, Qing Liu, Qiong Yao, Peizhen Du, Kai Zhang, Qing Chen, Zexin Chen, Hong Zhang, Mei Tian
Journal of Nuclear Medicine Sep 2017, 58 (9) 1490-1497; DOI: 10.2967/jnumed.116.189290

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Alteration of Monoamine Receptor Activity and Glucose Metabolism in Pediatric Patients with Anticonvulsant-Induced Cognitive Impairment
Yuankai Zhu, Jianhua Feng, Jianfeng Ji, Haifeng Hou, Lin Chen, Shuang Wu, Qing Liu, Qiong Yao, Peizhen Du, Kai Zhang, Qing Chen, Zexin Chen, Hong Zhang, Mei Tian
Journal of Nuclear Medicine Sep 2017, 58 (9) 1490-1497; DOI: 10.2967/jnumed.116.189290
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