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Figures
- FIGURE 1.
Anterior planar scintigrams of 2 patients 18 h after intravenous application of 6.0 GBq of 177Lu-PSMA-617 (A) and 24 h after intravenous application of 7.4 GBq of 177Lu-PSMA I&T (B). Both patients had minimal residual disease after prior RLT, not visible on scintigraphy.
- FIGURE 2.
Proposed protocol for repeated 177Lu-PSMA RLT. RLT is performed by repeated application of 177Lu-PSMA at 8-wk intervals, with follow-up assessment at 4-wk intervals. PSMA-directed PET/CT is performed at baseline and after 2 cycles of therapy. (Adapted with permission of (33).)
- FIGURE 3.
68Ga-PSMA-11 PET/CT at baseline and after 2 cycles of 177Lu-PSMA-617 in 78-y-old patient with mCRPC. Whole-body 68Ga-PSMA-11 PET maximum-intensity projections (A and B) and axial PET/CT scans (C and D) of thorax are shown at baseline (A and C) and after therapy (B and D). 68Ga-PSMA-11 PET demonstrates considerable reduction of PSMA-expressing metastases in lymph nodes and bone after 2 cycles, each with 6.0 GBq of 177Lu-PSMA-617. Serum PSA level decreased from 11.5 to 1.2 ng/mL.
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