PT - JOURNAL ARTICLE AU - Wolfgang P. Fendler AU - Kambiz Rahbar AU - Ken Herrmann AU - Clemens Kratochwil AU - Matthias Eiber TI - <sup>177</sup>Lu-PSMA Radioligand Therapy for Prostate Cancer AID - 10.2967/jnumed.117.191023 DP - 2017 Aug 01 TA - Journal of Nuclear Medicine PG - 1196--1200 VI - 58 IP - 8 4099 - http://jnm.snmjournals.org/content/58/8/1196.short 4100 - http://jnm.snmjournals.org/content/58/8/1196.full SO - J Nucl Med2017 Aug 01; 58 AB - 177Lu-prostate-specific membrane antigen (PSMA) radioligand therapy (RLT) using inhibitors of PSMA is a novel therapeutic option in patients with metastatic castration-resistant prostate cancer. The current literature suggests that this therapy is well tolerated and effective. On the basis of clinical need and current evidence, the therapy is being implemented in a growing number of centers worldwide. Here, we review important aspects of 177Lu-PSMA RLT, including patient stratification, the therapy protocol, concomitant medication, and follow-up, to inform medical staff involved in the RLT and care of patients with metastatic castration-resistant prostate cancer.