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Research ArticleOncology

Multiparametric Imaging of Tumor Hypoxia and Perfusion with 18F-Fluoromisonidazole Dynamic PET in Head and Neck Cancer

Milan Grkovski, Heiko Schöder, Nancy Y. Lee, Sean D. Carlin, Bradley J. Beattie, Nadeem Riaz, Jonathan E. Leeman, Joseph A. O’Donoghue and John L. Humm
Journal of Nuclear Medicine July 2017, 58 (7) 1072-1080; DOI: https://doi.org/10.2967/jnumed.116.188649
Milan Grkovski
1Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York
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Heiko Schöder
2Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York; and
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Nancy Y. Lee
3Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York
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Sean D. Carlin
2Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York; and
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Bradley J. Beattie
1Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York
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Nadeem Riaz
3Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York
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Jonathan E. Leeman
3Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York
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Joseph A. O’Donoghue
1Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York
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John L. Humm
1Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York
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Article Information

vol. 58 no. 7 1072-1080
DOI 
https://doi.org/10.2967/jnumed.116.188649
PubMed 
28183993

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication December 14, 2016
  • Accepted for publication January 2, 2017
  • Published online July 3, 2017.

Article Versions

  • previous version (February 9, 2017 - 04:22).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2017 by the Society of Nuclear Medicine and Molecular Imaging.

Author Information

  1. Milan Grkovski1,
  2. Heiko Schöder2,
  3. Nancy Y. Lee3,
  4. Sean D. Carlin2,
  5. Bradley J. Beattie1,
  6. Nadeem Riaz3,
  7. Jonathan E. Leeman3,
  8. Joseph A. O’Donoghue1 and
  9. John L. Humm1
  1. 1Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York
  2. 2Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York; and
  3. 3Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York
  1. For correspondence or reprints contact: Milan Grkovski, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, 1275 York Ave., New York, NY 10065. E-mail: grkovskm{at}mkscc.org
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Journal of Nuclear Medicine: 58 (7)
Journal of Nuclear Medicine
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July 1, 2017
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Multiparametric Imaging of Tumor Hypoxia and Perfusion with 18F-Fluoromisonidazole Dynamic PET in Head and Neck Cancer
Milan Grkovski, Heiko Schöder, Nancy Y. Lee, Sean D. Carlin, Bradley J. Beattie, Nadeem Riaz, Jonathan E. Leeman, Joseph A. O’Donoghue, John L. Humm
Journal of Nuclear Medicine Jul 2017, 58 (7) 1072-1080; DOI: 10.2967/jnumed.116.188649

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Multiparametric Imaging of Tumor Hypoxia and Perfusion with 18F-Fluoromisonidazole Dynamic PET in Head and Neck Cancer
Milan Grkovski, Heiko Schöder, Nancy Y. Lee, Sean D. Carlin, Bradley J. Beattie, Nadeem Riaz, Jonathan E. Leeman, Joseph A. O’Donoghue, John L. Humm
Journal of Nuclear Medicine Jul 2017, 58 (7) 1072-1080; DOI: 10.2967/jnumed.116.188649
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Keywords

  • 18F-fluoromisonidazole
  • FMISO
  • hypoxia
  • perfusion
  • dynamic PET
  • head and neck cancer
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