Real-Time Microfluidic Blood-Counting System for PET and SPECT Preclinical Pharmacokinetic Studies

Laurence Convert; Réjean Lebel; Suzanne Gascon; Réjean Fontaine; Jean-François Pratte; Paul Charette; Vincent Aimez; Roger Lecomte

doi:10.2967/jnumed.115.162768

Research ArticleBasic Science Investigations

Real-Time Microfluidic Blood-Counting System for PET and SPECT Preclinical Pharmacokinetic Studies

Laurence Convert, Réjean Lebel, Suzanne Gascon, Réjean Fontaine, Jean-François Pratte, Paul Charette, Vincent Aimez and Roger Lecomte

Journal of Nuclear Medicine September 2016, 57 (9) 1460-1466; DOI: https://doi.org/10.2967/jnumed.115.162768

Laurence Convert

1Sherbrooke Molecular Imaging Centre of CRCHUS and Department of Nuclear Medicine and Radiobiology, Université de Sherbrooke, Sherbrooke, Quebec, Canada

2Laboratoire Nanotechnologies Nanosystèmes (LN2)–CNRS UMI-3463, Université de Sherbrooke, Sherbrooke, Quebec, Canada; and

3Institut Interdisciplinaire d’Innovation Technologique (3IT), Université de Sherbrooke, Sherbrooke, Quebec, Canada

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Réjean Lebel

1Sherbrooke Molecular Imaging Centre of CRCHUS and Department of Nuclear Medicine and Radiobiology, Université de Sherbrooke, Sherbrooke, Quebec, Canada

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Suzanne Gascon

1Sherbrooke Molecular Imaging Centre of CRCHUS and Department of Nuclear Medicine and Radiobiology, Université de Sherbrooke, Sherbrooke, Quebec, Canada

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Réjean Fontaine

3Institut Interdisciplinaire d’Innovation Technologique (3IT), Université de Sherbrooke, Sherbrooke, Quebec, Canada

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Jean-François Pratte

3Institut Interdisciplinaire d’Innovation Technologique (3IT), Université de Sherbrooke, Sherbrooke, Quebec, Canada

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Paul Charette

2Laboratoire Nanotechnologies Nanosystèmes (LN2)–CNRS UMI-3463, Université de Sherbrooke, Sherbrooke, Quebec, Canada; and

3Institut Interdisciplinaire d’Innovation Technologique (3IT), Université de Sherbrooke, Sherbrooke, Quebec, Canada

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Vincent Aimez

2Laboratoire Nanotechnologies Nanosystèmes (LN2)–CNRS UMI-3463, Université de Sherbrooke, Sherbrooke, Quebec, Canada; and

3Institut Interdisciplinaire d’Innovation Technologique (3IT), Université de Sherbrooke, Sherbrooke, Quebec, Canada

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Roger Lecomte

1Sherbrooke Molecular Imaging Centre of CRCHUS and Department of Nuclear Medicine and Radiobiology, Université de Sherbrooke, Sherbrooke, Quebec, Canada

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Real-Time Microfluidic Blood-Counting System for PET and SPECT Preclinical Pharmacokinetic Studies

Laurence Convert, Réjean Lebel, Suzanne Gascon, Réjean Fontaine, Jean-François Pratte, Paul Charette, Vincent Aimez, Roger Lecomte

Journal of Nuclear Medicine Sep 2016, 57 (9) 1460-1466; DOI: 10.2967/jnumed.115.162768

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Real-Time Microfluidic Blood-Counting System for PET and SPECT Preclinical Pharmacokinetic Studies

Laurence Convert, Réjean Lebel, Suzanne Gascon, Réjean Fontaine, Jean-François Pratte, Paul Charette, Vincent Aimez, Roger Lecomte

Journal of Nuclear Medicine Sep 2016, 57 (9) 1460-1466; DOI: 10.2967/jnumed.115.162768

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Keywords

Pharmacokinetic studies
Microfluidic
arterial input function
small animal PET
small animal SPECT

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