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Research ArticleBasic Science Investigations

Preclinical Evaluation of 18F-Labeled Anti-HER2 Nanobody Conjugates for Imaging HER2 Receptor Expression by Immuno-PET

Ganesan Vaidyanathan, Darryl McDougald, Jaeyeon Choi, Eftychia Koumarianou, Douglas Weitzel, Takuya Osada, H. Kim Lyerly and Michael R. Zalutsky
Journal of Nuclear Medicine June 2016, 57 (6) 967-973; DOI: https://doi.org/10.2967/jnumed.115.171306
Ganesan Vaidyanathan
1Department of Radiology, Duke University Medical Center, Durham, North Carolina
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Darryl McDougald
1Department of Radiology, Duke University Medical Center, Durham, North Carolina
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Jaeyeon Choi
1Department of Radiology, Duke University Medical Center, Durham, North Carolina
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Eftychia Koumarianou
1Department of Radiology, Duke University Medical Center, Durham, North Carolina
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Douglas Weitzel
2Department of Radiation Oncology and Cancer Biology, Duke University Medical Center, Durham, North Carolina; and
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Takuya Osada
3Department of Surgery, Duke University Medical Center, Durham, North Carolina
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H. Kim Lyerly
3Department of Surgery, Duke University Medical Center, Durham, North Carolina
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Michael R. Zalutsky
1Department of Radiology, Duke University Medical Center, Durham, North Carolina
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Article Information

vol. 57 no. 6 967-973
DOI 
https://doi.org/10.2967/jnumed.115.171306
PubMed 
26912425

Published By 
Society of Nuclear Medicine
Print ISSN 
0161-5505
Online ISSN 
2159-662X
History 
  • Received for publication December 14, 2015
  • Accepted for publication February 3, 2016
  • Published online June 1, 2016.

Article Versions

  • previous version (February 18, 2016 - 10:23).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2016 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

Author Information

  1. Ganesan Vaidyanathan1,
  2. Darryl McDougald1,
  3. Jaeyeon Choi1,
  4. Eftychia Koumarianou1,
  5. Douglas Weitzel2,
  6. Takuya Osada3,
  7. H. Kim Lyerly3 and
  8. Michael R. Zalutsky1
  1. 1Department of Radiology, Duke University Medical Center, Durham, North Carolina
  2. 2Department of Radiation Oncology and Cancer Biology, Duke University Medical Center, Durham, North Carolina; and
  3. 3Department of Surgery, Duke University Medical Center, Durham, North Carolina
  1. For correspondence or reprints contact: Ganesan Vaidyanathan, Box 3808, Department of Radiology, Duke University Medical Center, Durham, NC 27710. E-mail: ganesan.v{at}duke.edu
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Journal of Nuclear Medicine: 57 (6)
Journal of Nuclear Medicine
Vol. 57, Issue 6
June 1, 2016
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Preclinical Evaluation of 18F-Labeled Anti-HER2 Nanobody Conjugates for Imaging HER2 Receptor Expression by Immuno-PET
Ganesan Vaidyanathan, Darryl McDougald, Jaeyeon Choi, Eftychia Koumarianou, Douglas Weitzel, Takuya Osada, H. Kim Lyerly, Michael R. Zalutsky
Journal of Nuclear Medicine Jun 2016, 57 (6) 967-973; DOI: 10.2967/jnumed.115.171306

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Preclinical Evaluation of 18F-Labeled Anti-HER2 Nanobody Conjugates for Imaging HER2 Receptor Expression by Immuno-PET
Ganesan Vaidyanathan, Darryl McDougald, Jaeyeon Choi, Eftychia Koumarianou, Douglas Weitzel, Takuya Osada, H. Kim Lyerly, Michael R. Zalutsky
Journal of Nuclear Medicine Jun 2016, 57 (6) 967-973; DOI: 10.2967/jnumed.115.171306
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Keywords

  • HER2
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  • immuno-PET
  • Residualizing label
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